A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells

Ling FENG; Yusheng Xie; Sung King Au-Yeung; Birhanu Hailu Hagos; Zhiyang Liu; Qingxin Chen; Jie Zhang; Qiuxiang Pang; Xi Yao; Mengsu Yang; Liang Zhang; Hongyan Sun

doi:10.1039/D0CC03069D

Author(s)

Birhanu Hailu Hagos
Jie Zhang
Qiuxiang Pang
Xi Yao
Mengsu Yang
Liang Zhang
Hongyan Sun

Related Research Unit(s)

Detail(s)

Original language	English
Pages (from-to)	8480-8483
Journal / Publication	Chemical Communications
Volume	56
Issue number	60
Online published	17 Jun 2020
Publication status	Published - 4 Aug 2020

Link(s)

DOI	DOI https://doi.org/10.1039/D0CC03069D Final Published version https://doi.org/10.1039/d0cc03069d Final Published version
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Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-85088848375&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(6fe64509-1227-40a4-80e7-eb34c6cb12ad).html

Abstract

A rotor-based probe MRMP-1 was designed and synthesized. MRMP-1 can bind to plasma membranes very quickly and stably with remarkable fluorescence enhancement. It can be used to monitor the dynamic changes in cell membranes in real-time under stimuli conditions. Importantly, MRMP-1 is the first rotor-based fluorescent sensor to label exosomes in living cells.

Citation Format(s)

[ RIS ] [ BibTeX ]

A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells. / FENG, Ling ; Xie, Yusheng ; Au-Yeung, Sung King; Hagos, Birhanu Hailu; Liu, Zhiyang ; Chen, Qingxin ; Zhang, Jie; Pang, Qiuxiang; Yao, Xi ; Yang, Mengsu ; Zhang, Liang ; Sun, Hongyan.

In: Chemical Communications, Vol. 56, No. 60, 04.08.2020, p. 8480-8483.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

FENG, L , Xie, Y , Au-Yeung, SK, Hagos, BH, Liu, Z , Chen, Q , Zhang, J, Pang, Q, Yao, X , Yang, M , Zhang, L & Sun, H 2020, 'A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells', Chemical Communications, vol. 56, no. 60, pp. 8480-8483. https://doi.org/10.1039/D0CC03069D, https://doi.org/10.1039/d0cc03069d

FENG, L., Xie, Y., Au-Yeung, S. K., Hagos, B. H., Liu, Z., Chen, Q., Zhang, J., Pang, Q., Yao, X., Yang, M., Zhang, L., & Sun, H. (2020). A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells. Chemical Communications, 56(60), 8480-8483. https://doi.org/10.1039/D0CC03069D, https://doi.org/10.1039/d0cc03069d

FENG L , Xie Y , Au-Yeung SK, Hagos BH, Liu Z , Chen Q et al. A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells. Chemical Communications. 2020 Aug 4;56(60):8480-8483. https://doi.org/10.1039/D0CC03069D, https://doi.org/10.1039/d0cc03069d

FENG, Ling ; Xie, Yusheng ; Au-Yeung, Sung King ; Hagos, Birhanu Hailu ; Liu, Zhiyang ; Chen, Qingxin ; Zhang, Jie ; Pang, Qiuxiang ; Yao, Xi ; Yang, Mengsu ; Zhang, Liang ; Sun, Hongyan. / A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells. In: Chemical Communications. 2020 ; Vol. 56, No. 60. pp. 8480-8483.