A disulfide-linked conjugate of ferrocenyl chalcone and silicon(iv) phthalocyanine as an activatable photosensitiser

Janet T. F. Lau; Xiong-Jie Jiang; Dennis K. P. Ng; Pui-Chi Lo

doi:10.1039/c2cc37251g

A disulfide-linked conjugate of ferrocenyl chalcone and silicon(iv) phthalocyanine as an activatable photosensitiser

Janet T. F. Lau
, Xiong-Jie Jiang
, Dennis K. P. Ng
, Pui-Chi Lo

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

64 Citations (Scopus)

Abstract

A novel bis(ferrocenyl chalcone) silicon(iv) phthalocyanine has been prepared in which the disulfide linker can be cleaved by dithiothreitol. The separation of the ferrocenyl quencher and the phthalocyanine core greatly enhances the fluorescence emission, singlet oxygen production and in vitro photocytotoxicity. © 2013 The Royal Society of Chemistry.

Original language	English
Pages (from-to)	4274-4276
Journal	Chemical Communications
Volume	49
Issue number	39
DOIs	https://doi.org/10.1039/c2cc37251g
Publication status	Published - 14 May 2013
Externally published	Yes

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title = "A disulfide-linked conjugate of ferrocenyl chalcone and silicon(iv) phthalocyanine as an activatable photosensitiser",

abstract = "A novel bis(ferrocenyl chalcone) silicon(iv) phthalocyanine has been prepared in which the disulfide linker can be cleaved by dithiothreitol. The separation of the ferrocenyl quencher and the phthalocyanine core greatly enhances the fluorescence emission, singlet oxygen production and in vitro photocytotoxicity. {\textcopyright} 2013 The Royal Society of Chemistry.",

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AU - Lau, Janet T. F.

AU - Jiang, Xiong-Jie

AU - Ng, Dennis K. P.

AU - Lo, Pui-Chi

PY - 2013/5/14

Y1 - 2013/5/14

N2 - A novel bis(ferrocenyl chalcone) silicon(iv) phthalocyanine has been prepared in which the disulfide linker can be cleaved by dithiothreitol. The separation of the ferrocenyl quencher and the phthalocyanine core greatly enhances the fluorescence emission, singlet oxygen production and in vitro photocytotoxicity. © 2013 The Royal Society of Chemistry.

AB - A novel bis(ferrocenyl chalcone) silicon(iv) phthalocyanine has been prepared in which the disulfide linker can be cleaved by dithiothreitol. The separation of the ferrocenyl quencher and the phthalocyanine core greatly enhances the fluorescence emission, singlet oxygen production and in vitro photocytotoxicity. © 2013 The Royal Society of Chemistry.

UR - https://www.scopus.com/pages/publications/84876513729

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84876513729&origin=recordpage

U2 - 10.1039/c2cc37251g

DO - 10.1039/c2cc37251g

M3 - RGC 21 - Publication in refereed journal

C2 - 23135340

SN - 0009-241X

VL - 49

SP - 4274

EP - 4276

JO - Chemical Communications

JF - Chemical Communications

IS - 39

ER -

A disulfide-linked conjugate of ferrocenyl chalcone and silicon(iv) phthalocyanine as an activatable photosensitiser

Abstract

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