A continuous optically-induced cell electroporation device with on-chip medium exchange mechanisms

Chia-Jung Chang; Ming-Yu Lu; Gwo-Bin Lee

doi:10.1109/MEMSYS.2014.6765618

A continuous optically-induced cell electroporation device with on-chip medium exchange mechanisms

Chia-Jung Chang, Ming-Yu Lu, Gwo-Bin Lee^*

^*Corresponding author for this work

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

1 Citation (Scopus)

Abstract

We present a new design for continuous optically-induced electroporation (OIE) on a microfluidic device, which is capable of replacing culture medium and electroporation buffer in a seamless fashion. The seamless on-chip integration of medium exchange mechanisms and optically-induced electroporation device could avoid critical issues such as cell losses and cell damage during manual operation in the traditional centrifuge system, and is therefore suitable for handling small or rare cell population. Furthermore, the survival rate of the cells could be greatly improved due to this fast, automatic procedure. © 2014 IEEE.

Original language	English
Title of host publication	MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems
Publisher	IEEE
Pages	234-237
ISBN (Print)	9781479935086
DOIs	https://doi.org/10.1109/MEMSYS.2014.6765618
Publication status	Published - 2014
Externally published	Yes
Event	27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014 - San Francisco, CA, United States Duration: 26 Jan 2014 → 30 Jan 2014

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)	1084-6999

Conference

Conference	27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014
Country/Territory	United States
City	San Francisco, CA
Period	26/01/14 → 30/01/14

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Access Output

10.1109/MEMSYS.2014.6765618

Other Access Options

Check CityUHK Library

Permanent Link

Right click to copy link

Cite this

Chang, C.-J., Lu, M.-Y., & Lee, G.-B. (2014). A continuous optically-induced cell electroporation device with on-chip medium exchange mechanisms. In MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems (pp. 234-237). Article 6765618 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). IEEE. https://doi.org/10.1109/MEMSYS.2014.6765618

@inproceedings{a15f1f6b3e3c48faa6c8ff31905b56a6,

title = "A continuous optically-induced cell electroporation device with on-chip medium exchange mechanisms",

abstract = "We present a new design for continuous optically-induced electroporation (OIE) on a microfluidic device, which is capable of replacing culture medium and electroporation buffer in a seamless fashion. The seamless on-chip integration of medium exchange mechanisms and optically-induced electroporation device could avoid critical issues such as cell losses and cell damage during manual operation in the traditional centrifuge system, and is therefore suitable for handling small or rare cell population. Furthermore, the survival rate of the cells could be greatly improved due to this fast, automatic procedure. {\textcopyright} 2014 IEEE.",

author = "Chia-Jung Chang and Ming-Yu Lu and Gwo-Bin Lee",

note = "Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].; 27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014 ; Conference date: 26-01-2014 Through 30-01-2014",

year = "2014",

doi = "10.1109/MEMSYS.2014.6765618",

language = "English",

isbn = "9781479935086",

series = "Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)",

publisher = "IEEE",

pages = "234--237",

booktitle = "MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems",

address = "United States",

}

Chang, C-J, Lu, M-Y & Lee, G-B 2014, A continuous optically-induced cell electroporation device with on-chip medium exchange mechanisms. in MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems., 6765618, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), IEEE, pp. 234-237, 27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014, San Francisco, CA, United States, 26/01/14. https://doi.org/10.1109/MEMSYS.2014.6765618

A continuous optically-induced cell electroporation device with on-chip medium exchange mechanisms. / Chang, Chia-Jung; Lu, Ming-Yu; Lee, Gwo-Bin.
MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems. IEEE, 2014. p. 234-237 6765618 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

TY - GEN

T1 - A continuous optically-induced cell electroporation device with on-chip medium exchange mechanisms

AU - Chang, Chia-Jung

AU - Lu, Ming-Yu

AU - Lee, Gwo-Bin

N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

PY - 2014

Y1 - 2014

N2 - We present a new design for continuous optically-induced electroporation (OIE) on a microfluidic device, which is capable of replacing culture medium and electroporation buffer in a seamless fashion. The seamless on-chip integration of medium exchange mechanisms and optically-induced electroporation device could avoid critical issues such as cell losses and cell damage during manual operation in the traditional centrifuge system, and is therefore suitable for handling small or rare cell population. Furthermore, the survival rate of the cells could be greatly improved due to this fast, automatic procedure. © 2014 IEEE.

AB - We present a new design for continuous optically-induced electroporation (OIE) on a microfluidic device, which is capable of replacing culture medium and electroporation buffer in a seamless fashion. The seamless on-chip integration of medium exchange mechanisms and optically-induced electroporation device could avoid critical issues such as cell losses and cell damage during manual operation in the traditional centrifuge system, and is therefore suitable for handling small or rare cell population. Furthermore, the survival rate of the cells could be greatly improved due to this fast, automatic procedure. © 2014 IEEE.

UR - http://www.scopus.com/inward/record.url?scp=84899033261&partnerID=8YFLogxK

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84899033261&origin=recordpage

U2 - 10.1109/MEMSYS.2014.6765618

DO - 10.1109/MEMSYS.2014.6765618

M3 - RGC 32 - Refereed conference paper (with host publication)

SN - 9781479935086

T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

SP - 234

EP - 237

BT - MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems

PB - IEEE

T2 - 27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014

Y2 - 26 January 2014 through 30 January 2014

ER -

Chang CJ, Lu MY, Lee GB. A continuous optically-induced cell electroporation device with on-chip medium exchange mechanisms. In MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems. IEEE. 2014. p. 234-237. 6765618. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). doi: 10.1109/MEMSYS.2014.6765618

A continuous optically-induced cell electroporation device with on-chip medium exchange mechanisms

Abstract

Publication series

Conference

Bibliographical note

Access Output

Other Access Options

Permanent Link

Other Files and Links

Fingerprint

Cite this