A comparative proteomic study on the effects of metal pollution in oysters Crassostrea hongkongensis

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

12 Scopus Citations
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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)436-442
Journal / PublicationMarine Pollution Bulletin
Volume112
Issue number1-2
Online published9 Jul 2016
Publication statusPublished - 15 Nov 2016
Externally publishedYes

Abstract

The metal pollution has posed great risk on the coastal organisms along the Jiulongjiang Estuary in South China. In this work, two-dimensional electrophoresis-based proteomics was applied to the oysters Crassostrea hongkongensis from metal pollution sites to characterize the proteomic responses to metal pollution. Metal accumulation and proteomic responses indicated that the oysters from BJ site were more severely contaminated than those from FG site. Compared with those oyster samples from the clean site (JZ), metal pollution induced cellular injuries, oxidative and immune stresses in oyster heapatopancreas from both BJ and FG sites via differential metabolic pathways. In addition, metal pollution in BJ site induced disturbance in energy and lipid metabolisms in oysters. Results indicated that cathepsin L and ferritin GF1 might be the biomarkers of As and Fe in oyster C. hongkongensis, respectively. This study demonstrates that proteomics is a useful tool for investigating biological effects induced by metal pollution.

Research Area(s)

  • Crassostrea hongkongensis, Hepatopancreas, Metal pollution, Proteomics