TY - CHAP
T1 - A Brief Review on the Ecological Network Analysis with Applications in the Emerging Medical Ecology
AU - Ma, Zhanshan (Sam)
AU - Zhang, Chengchen
AU - Zhang, Qingpeng
AU - Li, Jie
AU - Li, Lianwei
AU - Qi, Linyi
AU - Yang, Xianghong
PY - 2016
Y1 - 2016
N2 - Ecology studies the relationship between organisms and their environment, and a well-accepted paradigm of ecological science is to divide the subject into molecular ecology, autecology, population ecology, community ecology, ecosystem ecology, and landscape ecology, according to the scale of investigation. Network analysis can arguably be a powerful tool for any scale of the ecological research because it is particularly suitable for investigating the complex relationships in multivariate and multidimensional settings. In this article, we present a glimpse of the state-of-the-art research in ecological network analysis, focusing on the species interaction network (SIN) in the human microbiome. Our choice of the focus takes advantage of the recent revolutionary metagenomic technology that has open unprecedented opportunities to the study of microbial communities, especially the human microbiome. We also present a case study to demonstrate the analysis of SINs in both healthy and diseased oral microbiomes. The analysis reveals striking characteristic changes in the human oral microbiome associated with the transition from healthy regime to periodontitis regime. © Springer-Verlag Berlin Heidelberg 2016
AB - Ecology studies the relationship between organisms and their environment, and a well-accepted paradigm of ecological science is to divide the subject into molecular ecology, autecology, population ecology, community ecology, ecosystem ecology, and landscape ecology, according to the scale of investigation. Network analysis can arguably be a powerful tool for any scale of the ecological research because it is particularly suitable for investigating the complex relationships in multivariate and multidimensional settings. In this article, we present a glimpse of the state-of-the-art research in ecological network analysis, focusing on the species interaction network (SIN) in the human microbiome. Our choice of the focus takes advantage of the recent revolutionary metagenomic technology that has open unprecedented opportunities to the study of microbial communities, especially the human microbiome. We also present a case study to demonstrate the analysis of SINs in both healthy and diseased oral microbiomes. The analysis reveals striking characteristic changes in the human oral microbiome associated with the transition from healthy regime to periodontitis regime. © Springer-Verlag Berlin Heidelberg 2016
U2 - 10.1007/8623_2016_204
DO - 10.1007/8623_2016_204
M3 - RGC 12 - Chapter in an edited book (Author)
SN - 978-3-662-49309-0
SN - 978-3-662-57000-5
T3 - Springer Protocols Handbooks
SP - 7
EP - 39
BT - Hydrocarbon and Lipid Microbiology Protocols
A2 - Terry J. McGenity, null
A2 - Kenneth N. Timmis, null
A2 - Balbina Nogales Fernández, null
PB - Springer
CY - Berlin, Heidelberg
ER -