3D-printed microneedles with open groove channels for liquid extraction

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

21 Scopus Citations
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Detail(s)

Original languageEnglish
Article number20210109
Number of pages6
Journal / PublicationExploration
Volume1
Issue number3
Online published28 Dec 2021
Publication statusPublished - Dec 2021

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Abstract

Microneedles (MNs) offer a simple and minimally invasive way to sample skin interstitial fluid for bioanalysis. Through the integration with portable or wearable sensing devices, it allows us to get qualitative information about some biomarkers in situ. This work is to show aMN platform with open groove channels that are manufactured using photopolymerization 3D printing. The grooves on the needle surface permit that liquid flows from the tips to the base under the influence of capillary force. The ultimate MN device can penetrate skin and tissues and sample liquid in the skin model. By taking the glucose as the model biomarker, we demonstrate that the biomarkers in the extracted liquid can be analyzed in situ by the commercial test strips attached to the back.

© 2021 The Authors. Exploration published by Henan University and John Wiley & Sons Australia, Ltd

Research Area(s)

  • 3D printing, glucose sensing, liquid extraction, microneedle

Citation Format(s)

3D-printed microneedles with open groove channels for liquid extraction. / Leng, Fang; Zheng, Mengjia; Xu, Chenjie.
In: Exploration, Vol. 1, No. 3, 20210109, 12.2021.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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