TY - GEN
T1 - 2-dimensional SPR detection system integrated with molecular imprinting polymer microarrays using microfluidic technology
AU - Lee, Kuo-Hoong
AU - Su, Yuan-Deng
AU - Chen, Shean-Jen
AU - Lee, Gwo-Bin
N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].
PY - 2006
Y1 - 2006
N2 - This paper reports a novel microfluidic chip integrated with arrayed molecular imprinting polymer (MIP) films for surface plasmon resonance (SPR) phase imaging of specific bio-samples. The SPR imaging system uses a surface-sensitive optical technique to detect two-dimensional spatial phase variation caused by bio-molecules absorbed on a sensing surface composed of highly-specific MIP films. The developed system has a high resolution and a high-throughput screening capability and has been successfully applied to the analysis of multiple bio-molecules without the need for additional labeling in long-term measuring. The innovative microfluidic chip is capable of transporting a specific amount of multiple bio-samples inside multiple microchannels using micropumps/microvalves to the sensing regions where arrayed MIP films are locally deposited such that highly-sensitive, highly-specific bio-sensing can be achieved. © 2006 IEEE.
AB - This paper reports a novel microfluidic chip integrated with arrayed molecular imprinting polymer (MIP) films for surface plasmon resonance (SPR) phase imaging of specific bio-samples. The SPR imaging system uses a surface-sensitive optical technique to detect two-dimensional spatial phase variation caused by bio-molecules absorbed on a sensing surface composed of highly-specific MIP films. The developed system has a high resolution and a high-throughput screening capability and has been successfully applied to the analysis of multiple bio-molecules without the need for additional labeling in long-term measuring. The innovative microfluidic chip is capable of transporting a specific amount of multiple bio-samples inside multiple microchannels using micropumps/microvalves to the sensing regions where arrayed MIP films are locally deposited such that highly-sensitive, highly-specific bio-sensing can be achieved. © 2006 IEEE.
KW - MEMS
KW - Microfluidic
KW - MIP
KW - SPR
UR - https://www.scopus.com/pages/publications/33750107190
UR - https://www.scopus.com/pages/publications/33750107190#tab=impact
U2 - 10.1109/memsys.2006.1627828
DO - 10.1109/memsys.2006.1627828
M3 - RGC 32 - Refereed conference paper (with host publication)
SN - 0780394755
SN - 9780780394759
VL - 2006
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 430
EP - 433
BT - 19th IEEE International Conference on Micro Electro Mechanical Systems
T2 - 19th IEEE International Conference on Micro Electro Mechanical Systems
Y2 - 22 January 2006 through 26 January 2006
ER -