医用钛表面纳米薄膜的制备及生物相容性研究

We used a hydrothermal technique to synthesize one-dimensional titanium oxide on titanium plate in a teflon reaction kettle. The hydrothermal treated plates were subsequently immersed in simulated body fluid for further biocompatibility studies. TEM, SEM, XRD and FTIR were used to investigate the structure and microcosmic morphology of the nanostructure before and after mineralization. The effect of the time on the crystal structures and microcosmic morphology of the samples were studied and the formation mechanism of the nanostructure were discussed. The results show that a neat, uniform size of nano film structure can be formed through hydrothermal reaction of titanium and NaOH aqueous solution. When titanium reacts with 6 mol/L NaOH solution at 180℃, the nanostructures can be formed in only half 1 h, and reaction time has an effect on the size and structure of the nanofilm. After immersed in SBF for 7 d, it can induce apatite deposit to its surface.