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医用钛合金表面仿生纳米结构的构建

Translated title of the contribution: Design of Biomimetic Nano-Architectures on Biomedical Titanium
  • 吴水林
  • , 刘想梅
  • , Hoi Man Wong
  • , 王文浩
  • , 杨伟国
  • , 朱剑豪

    Research output: Conference PapersRGC 32 - Refereed conference paper (without host publication)peer-review

    Abstract

    鈦及其合金材料廣泛地用在矯形外科及骨組織修復領域。但是鈦及鈦合金表面自發形成的TiO2保護膜缺乏生物活性,植入體內後,不利於細胞的粘附和分化,新生的骨組織與植入體結合性差,在承受外加載荷時,容易鬆動,從而導致植入體失效。本研究探索鈦合金在水熱條件下,通過表面金屬鈦與鹼液的反應原位生長出一層一維鈦酸鹽納米線,之後通過在人體模擬液中浸泡,實現一維納米線與模擬液中Ca/P離​​子的交換,誘導納米磷灰石在一維鈦酸鹽納米線表面生長,從而在鈦合金表面實現分級仿生結構。 TEM, FE-SEM, XRD, FTIR和EDX 等測試手段用來表徵樣品礦化前後鈦片表面的微觀形貌、結構及元素組成。體外細胞實驗表明,這種分級仿生納米結構能夠有利於成骨細胞的粘附,並顯著促進細胞的增殖與分化 [1-3]。
    Translated title of the contributionDesign of Biomimetic Nano-Architectures on Biomedical Titanium
    Original languageChinese (Simplified)
    Publication statusPublished - Dec 2013
    EventChinese Society of Biomaterials Conference 2013 - Shenzhen Exhibition Center, Shenzhen, China
    Duration: 20 Dec 201323 Dec 2013

    Conference

    ConferenceChinese Society of Biomaterials Conference 2013
    PlaceChina
    CityShenzhen
    Period20/12/1323/12/13

    Bibliographical note

    Information for this record is supplemented by the author(s) concerned.

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