Abstract
BVD is one of the most important diseases with significant economic losses in dairy cattle industry throughout the world. This virus can result in a wide range of clinical manifestations that may lead to congenital defect as consequences. The aim of this paper is to introduce a type of congenital disorder mainly associated with tremor that occurred in two parts of Iran for the first time.
In two modem dairies of Tehran and Kerman, 1 and 3 neonate calves with neurologic signs were further examined clinically, histopathologically and serologically. Blood sample and half of the brain of the calf from Tehran's farm as well as blood samples of 3 affected and alive calves and those of 5 mothers of the affected calves (3 alive and 2 died) and 5 partners of these mothers from Kerman's farm were sent to a lab. For BVDV antigen detection, the brain underwent RT-PCR examination. For BVDV antigen and antibody determination, the blood samples were examined by capture and indirect ELISA, respectively. Meanwhile, the other half of the brain of the calf from Tehran's farm was histopathologically studied.
Microscopic examinations revealed considerable injuries in white and gray matter of brain referred to lymphocytic encephalitis, more likely viral encephalitis. All of the 3 calves were positive for Ag and Ab tests. All of the mothers had only antibodies against BVDV. The partners were the same as the mothers with one exception (which was negative in both tests). Considering the high prevalence of virus and economical losses due to infection with BVDV in Iran, adopting an appropriate and precise control strategy in whole parts of country seems vital.
In two modem dairies of Tehran and Kerman, 1 and 3 neonate calves with neurologic signs were further examined clinically, histopathologically and serologically. Blood sample and half of the brain of the calf from Tehran's farm as well as blood samples of 3 affected and alive calves and those of 5 mothers of the affected calves (3 alive and 2 died) and 5 partners of these mothers from Kerman's farm were sent to a lab. For BVDV antigen detection, the brain underwent RT-PCR examination. For BVDV antigen and antibody determination, the blood samples were examined by capture and indirect ELISA, respectively. Meanwhile, the other half of the brain of the calf from Tehran's farm was histopathologically studied.
Microscopic examinations revealed considerable injuries in white and gray matter of brain referred to lymphocytic encephalitis, more likely viral encephalitis. All of the 3 calves were positive for Ag and Ab tests. All of the mothers had only antibodies against BVDV. The partners were the same as the mothers with one exception (which was negative in both tests). Considering the high prevalence of virus and economical losses due to infection with BVDV in Iran, adopting an appropriate and precise control strategy in whole parts of country seems vital.
| Translated title of the contribution | Occurrence of congenital tremor in Holstein calves due to infection with BVDV in two industrial dairies from Tehran and Kerman provinces |
|---|---|
| Original language | Farsi |
| Pages (from-to) | 92-96 |
| Journal | Iranian Veterinary Journal |
| Volume | 7 |
| Issue number | 3 |
| Publication status | Published - 2011 |
| Externally published | Yes |
Bibliographical note
Research Unit(s) information for this publication is provided by the author(s) concerned.Research Keywords
- CONGENITAL TREMOR
- HOLSTEIN CALF
- BVDV
- TEHRAN
- KERMAN