Topology and Cooperative Reactivity of Shape-Persistent Multimetallic Frameworks
DescriptionInspired by nature, cooperative reactivity between metal centers in close proximity has attracted intense interest. While metalloenzymes have distinct advantages conferred by the surrounding protein envelope, the development of cooperative multimetallic systems displaying desirable reactivity and selectivity remains a challenging yet worthwhile goal. This proposal is dedicated towards the design, preparation, and function of multinuclear assemblies featuring reactive metal-organic subunits in face-to-face geometry that are stacked together by a rigid anchoring group. Such a conformation allows minimal lateral displacement but a degree of rotational flexibility for the subunits. By changing the nature and dimensions of the metal-organic and anchoring components, and thereby varying their relative spatial arrangement (topology) and electronic properties, the capacity of the resultant frameworks for binding and activation of small molecules can be examined and adjusted. It is envisaged that a synergistic and tunable reaction space between the metal centers can be generated. Compared with previous studies in this area, novel approaches are proposed which can modify and enhance the reactivity of bound substrates. The underlying aim is to develop reactivity and catalytic applications for these bimetallic frameworks, for example in the production of biodegradable polymers and chemicals using sustainable resources.
|Effective start/end date||1/01/11 → 22/06/15|