Synthesis, Structure and Reactivity of Two-coordinate Boron Cations, Boron Radicals and Boryl Anions
DescriptionThe aim of the proposed research will be to prepare novel two-coordinate organoboron compounds and investigate their reaction chemistry.Boron cations, boron radicals and boryl anions are intriguing chemical species. In recent years, boron cations and radicals have been used in synthetic chemistry as catalysts, key intermediates, and organic reagents to achieve various transformations. Boron-containing radicals have also found applications in chemical sensors, initiators for polymerization and novel materials for magnetic systems and organic electronics. Meanwhile, whereas most boron reagents have electrophilic boron centres, boryl anions are nucleophilic and could be developed as a new type of reagent for organic synthesis. Although these three types of boron compounds have been prepared and studied, the focus has been on three- or four-coordinate organoboron compounds or stabilization by donor ligands, which decreases the reactivity of the boron center. It is anticipated that two-coordinate boron species will have better reactivity. However, reported examples of two-coordinate compounds, especially those of two-coordinate boron radical and donor-free boryl anions, remain limited. The main challenge isto find a proper protecting group that inhibits dimerization and other intramolecular side reactions. In this proposed study, we plan to use a rigid aromatic-based functional group to synthesize a series of two-coordinate boron cation, boron radical and boryl anion compounds and to systematically study their reaction chemistry. It is anticipated that the boron cations and boron radicals will be utilizable in small molecule activation and in reactions with unsaturated compounds and hydrocarbons. It is also expected that the two-coordinate boryl anions can be prepared from different metal boryl species and used as nucleophiles for the construction of new boron-element bonds. The findings of this project will enrich our fundamental understanding of the chemistry of two coordinate organoboron compounds and their possible future applications.
|Effective start/end date||1/01/23 → …|