Dissecting Age-dependent Molecular Heterogeneity of Colorectal Cancer and Establishing a Probabilistic Model for Robust Prediction of High-risk Young-onset Colorectal Cancer Patients

Project: Research

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Research Output

  1. 2024
  2. Published

    GCclassifier: An R package for the prediction of molecular subtypes of gastric cancer

    Li, J., He, L., Zhang, X., Li, X., Wang, L., Zhu, Z. & Song, K. & 1 others, Wang, X., Dec 2024, In: Computational and Structural Biotechnology Journal. 23, p. 752-758

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 3
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  3. Published

    Low-dose ionizing radiation promotes motor recovery and brain rewiring by resolving inflammatory response after brain injury and stroke

    Au, N. P. B., Wu, T., Kumar, G., Jin, Y., Li, Y. Y. T., Chan, S. L. & Lai, J. H. C. & 4 others, Chan, K. W. Y., Yu, K. N., Wang, X. & Ma, C. H. E., Jan 2024, In: Brain, Behavior, and Immunity. 115, p. 43-63

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 4
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  4. 2023
  5. Published

    Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair

    Au, N. P. B., Wu, T., Chen, X., Gao, F., Li, Y. T. Y., Tam, W. Y. & Yu, K. N. & 4 others, Geschwind, D. H., Coppola, G., Wang, X. & Ma, C. H. E., 20 Dec 2023, In: Neuron. 111, 24, p. 3970-3987, e1-e8

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 4
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  6. Published

    Identification of subtype-specific master regulatory long non-coding RNAs of gastric cancer through a network-based approach

    Li, J., Song, K., Li, X., Wang, Y. & Wang, X., Dec 2023, Proceedings - 2023 IEEE International Conference on Bioinformatics and Biomedicine. Jiang, X., Wang, H., Alhajj, R., Hu, X., Engel, F., Mahmud, M., Pisanti, N., Cui, X. & Song, H. (eds.). p. 2777-2782

    Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

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  7. Published

    Deep learning-derived spatial organization features on histology images predicts prognosis in colorectal liver metastasis patients after hepatectomy

    Qi, L., Liang, J.-Y., Li, Z.-W., Xi, S.-Y., Lai, Y.-N., Gao, F. & Zhang, X.-R. & 8 others, Wang, D.-S., Hu, M.-T., Cao, Y., Xu, L.-J., Chan, R. C. K., Xing, B.-C., Wang, X. & Li, Y.-H., 20 Oct 2023, In: iScience. 26, 10, 107702.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 1
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  8. Published

    Integrative network analysis reveals subtype-specific long non-coding RNA regulatory mechanisms in head and neck squamous cell carcinoma

    Li, J., Wu, T., Song, K., Zhu, L., Wang, Y., Chen, T. & Wang, X., 2023, In: Computational and Structural Biotechnology Journal. 21, p. 535-549

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 8
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  9. 2022
  10. Published

    Dissecting super-enhancer heterogeneity: time to re-examine cancer subtypes?

    Wu, T., Huang, H. & Wang, X., Dec 2022, In: Trends in Genetics. 38, 12, p. 1199-1203 5 p.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 3
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  11. Published

    Quantitative proteomics reveals differential immunoglobulin-associated proteome (IgAP) in patients of acute myocardial infarction and chronic coronary syndromes

    Tan, M., Ma, J., Yang, X., You, Q., Guo, X., Li, Y. & Wang, R. & 5 others, Han, G., Chen, Y., Qiu, X., Wang, X. & Zhang, L., 10 Feb 2022, In: Journal of Proteomics. 252, 104449.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 4
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  12. Published

    TCOF1 upregulation in triple-negative breast cancer promotes stemness and tumour growth and correlates with poor prognosis

    Hu, J., Lai, Y., Huang, H., Ramakrishnan, S., Pan, Y., Ma, V. W. S. & Cheuk, W. & 8 others, So, G. Y. K., He, Q., Geoffrey Lau, C., Zhang, L., Cho, W. C. S., Chan, K. M., Wang, X. & Rebecca Chin, Y., 1 Jan 2022, In: British Journal of Cancer. 126, 1, p. 57-71

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 17
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  13. Published

    A microRNA-based liquid biopsy signature for the early detection of esophageal squamous cell carcinoma: a retrospective, prospective and multicenter study

    Miyoshi, J. (Co-first Author), Zhu, Z. (Co-first Author), Luo, A. (Co-first Author), Toden, S. (Co-first Author), Zhou, X., Izumi, D. & Kanda, M. & 11 others, Takayama, T., Parker, I. M., Wang, M., Gao, F., Zaidi, A. H., Baba, H., Kodera, Y., Cui, Y., Wang, X. (Co-first Author), Liu, Z. (Co-first Author) & Goel, A. (Co-first Author), 2022, In: Molecular Cancer. 21, 44.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 57
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  14. Published

    The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages

    Wu, J., Liu, Q., Zhang, X., Tan, M., Li, X., Liu, P. & Wu, L. & 6 others, Jiao, F., Lin, Z., Wu, X., Wang, X., Zhao, Y. & Ren, J., 2022, In: Cell Death and Disease. 13, 653.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 88
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  15. 2021
  16. Published

    Attention to time-of-day variability improves the reproducibility of gene expression patterns in multiple sclerosis

    Huang, S., Wu, T., Lau, A. Y., Au, C., Huang, H., Wang, X. & Kim, J. Y., 19 Nov 2021, In: iScience. 24, 11, 103247.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 4
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  17. Published

    An integrated workflow for biomarker development using microRNAs in extracellular vesicles for cancer precision medicine

    Chen, Y., Wu, T., Zhu, Z., Huang, H., Zhang, L., Goel, A. & Yang, M. & 1 others, Wang, X., Sept 2021, In: Seminars in Cancer Biology. 74, p. 134-155

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 14
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  18. Published

    Identification of prognostic spatial organization features in colorectal cancer microenvironment using deep learning on histopathology images

    Qi, L., Ke, J., Yu, Z., Cao, Y., Lai, Y., Chen, Y. & Gao, F. & 1 others, Wang, X., Sept 2021, In: Medicine in Omics. 2, 100008.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

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  19. Published

    Assessment of the Diagnostic Efficiency of a Liquid Biopsy Assay for Early Detection of Gastric Cancer

    Izumi, D., Zhu, Z., Chen, Y., Toden, S., Huo, X., Kanda, M. & Ishimoto, T. & 8 others, Gu, D., Tan, M., Kodera, Y., Baba, H., Li, W., Chen, J., Wang, X. & Goel, A., Aug 2021, In: JAMA Network Open. 4, 8, e2121129.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 28
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  20. Published

    OCaMIR—A noninvasive, diagnostic signature for early-stage ovarian cancer: A multi-cohort retrospective and prospective study

    Kandimalla, R., Wang, W., Yu, F., Zhou, N., Gao, F., Spillman, M. & Moukova, L. & 5 others, Slaby, O., Salhia, B., Zhou, S., Wang, X. & Goel, A., Aug 2021, In: Clinical Cancer Research. 27, 15, p. 4277-4286

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 19
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  21. Published

    Multi-Omics Data Fusion for Cancer Molecular Subtyping Using Sparse Canonical Correlation Analysis

    Qi, L., Wang, W., Wu, T., Zhu, L., He, L. & Wang, X., Jul 2021, In: Frontiers in Genetics. 12, 607817.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 15
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  22. Published

    NEM-Tar: A Probabilistic Graphical Model for Cancer Regulatory Network Inference and Prioritization of Potential Therapeutic Targets From Multi-Omics Data

    Zhang, Y., Zhu, L. & Wang, X., Apr 2021, In: Frontiers in Genetics. 12, 608042.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 2
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  23. Published

    Integrated regulatory network in Pseudomonas syringae reveals dynamics of virulence

    Shao, X., Tan, M., Xie, Y., Yao, C., Wang, T., Huang, H. & Zhang, Y. & 6 others, Ding, Y., Liu, J., Han, L., Hua, C., Wang, X. & Deng, X., 30 Mar 2021, In: Cell Reports. 34, 13, 108920.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 24
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  24. Published

    Profiling MicroRNAs with Associated Spatial Dynamics in Acute Tissue Slices

    Xie, K., Wang, Z., Qi, L., Zhao, X., Wang, Y., Qu, J. & Xu, P. & 5 others, Huang, L., Zhang, W., Yang, Y., Wang, X. & Shi, P., 23 Mar 2021, In: ACS Nano. 15, 3, p. 4881–4892

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 12
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