Development of a Robot-aided Optically Controlled Cell Testing Device for Drug Discovery
DescriptionThis project aims to develop a new robot-aided optically controlled cell testing device, for measurement and characterization of single cell behaviors and functions for drug discovery. The device integrates cutting-edge technologies of robotics and automation, optical tweezers, and microfluidic lab-on-a-chip, and can achieve stretching manipulation of single cells. Through sensing the mechanobiological signals of cells that have undergone drug treatment during the cell stretching manipulations, the data used for the assessment of drug effect can be collected. As a case study, the device will be used to manipulate and test brain neural cells treated by drugs for Alzheimer’s disease (AD). The success of this project will greatly benefit testing and certification services for pharmaceutical industry, and also contribute to the upgrading of healthcare product manufacturing in Hong Kong.
|Effective start/end date||1/02/16 → 15/03/16|