Detection, Localization and Assessment of Prostate Cancer Lesions Using Multiparametric Magnetic Resonance Imaging

Project: Research

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Prostate cancer is the third most common cancer in men in Hong Kong. With an increased survival rate of prostate cancer recently due to earlier diagnosis, more focus is now placed on obtaining an accurate risk assessment to optimize treatment decision. Multiparametric MRI (mpMRI) has been widely used for assessing patients with suspected prostate cancer and MRI-directed targeted biopsy is becoming a standard way for diagnosing prostate cancer. However, the current workflow for mpMRI interpretation is associated with a number of limitations. Firstly, substantial amount of time is needed for radiologists to review more than a thousand MR images for each patient and manually segment the prostate gland and lesions before a targeted biopsy could be performed. Secondly, mpMRI interpretation depends on the experience of the radiologist. Therefore, parallel to the development of MRI technology, an equally important requirement is to develop tools to automate accurate prostate cancer localization and risk assessment. This project focuses on the development of a streamlined and objective framework to delineate lesions and estimate their likelihood of being clinically significant cancers. Successful completion of this project will accelerate the current workflow and eliminate variability in MRI interpretation, thereby benefitting prostate cancer diagnosis and patient management.


Project number9440220
Grant typeITF
Effective start/end date1/07/1930/06/21