Analysis of Interface Patterns between Biomolecules Based on Alpha Shape Models

Project: Research

Research Output

  1. 2018
  2. Published

    Analysis of the Relative Movements Between EGFR and Drug Inhibitors Based on Molecular Dynamics Simulation

    Chen, L., Zou, B., Lee, V. H. F. & Yan, H., 2018, In: Current Bioinformatics. 13, 3, p. 299-309

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 4
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  3. Published

    Prediction of sensitivity to gefitinib/erlotinib for EGFR mutations in NSCLC based on structural interaction fingerprints and multilinear principal component analysis

    Zou, B., Lee, V. H. F. & Yan, H., 2018, In: BMC Bioinformatics. 19, 88.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 16
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  4. 2017
  5. Published

    An Eigen-Binding Site Based Method for the Analysis of Anti-EGFR Drug Resistance in Lung Cancer Treatment

    Ma, L., Wang, D. D., Zou, B. & Yan, H., 1 Sep 2017, In: IEEE/ACM Transactions on Computational Biology and Bioinformatics. 14, 5, p. 1187-1194

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 10
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  6. Published

    Deciphering mechanisms of acquired T790M mutation after EGFR inhibitors for NSCLC by computational simulations

    Zou, B., Lee, V. H. F., Chen, L., Ma, L., Wang, D. D. & Yan, H., 2017, In: Scientific Reports. 7, 6595.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 24
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  7. 2016
  8. Published

    A computational study of three frequent mutations of EGFR and their effects on protein dimer formation and non-small cell lung cancer drug resistance

    Shen, Z., Wang, D. D., Ma, L., Yan, H., Wong, M. P. & Lee, V. H. F., Jul 2016, In: Current Bioinformatics. 11, 3, p. 382-391

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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  9. Published

    Analysis of the relationship between lung cancer drug response level and atom connectivity dynamics based on trimmed Delaunay triangulation

    Zou, B., Wang, D. D., Ma, L., Chen, L. & Yan, H., 16 May 2016, In: Chemical Physics Letters. 652, p. 117-122

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 7
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  10. Published

    Identifying EGFR mutation-induced drug resistance based on alpha shape model analysis of the dynamics

    Ma, L., Zou, B. & Yan, H., 2016, In: Proteome Science. 14, 12.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 11
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