Dr. ZHENG Zongli (鄭宗立)
Research Output
- 2022
- Published
High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination
Yuen, C. T. L., Thean, D. G. L., Chan, B. K. C., Zhou, P., Kwok, C. C. S., Chu, H. Y., Cheung, M. S. H., & 7 others , 22 Feb 2022, In: Nucleic Acids Research. 50, 3, p. 1650-1660Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 2 - Published
Deep RNA Sequencing Revealed Fusion Junctional Heterogeneity May Predict Crizotinib Treatment Efficacy in ALK-Rearranged NSCLC
Song, Z., Lian, S., Mak, S., Chow, M. Z., Xu, C., Wang, W., Keung, H. Y., & 7 others , Feb 2022, In: Journal of Thoracic Oncology. 17, 2, p. 264-276 13 p.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 8 - Accepted/In press/Filed
Methods and systems for measuring multiplex RNA expression
ZHENG, Z. & LU, C., 28 Jan 2022, (Accepted/In press/Filed) Priority No. 63/304,489Research output: Patents, Agreements and Assignments (RGC: 51, 52, 53) › 51_Patents granted (CityU only, data source from KTO)
- Published
Machine learning-coupled combinatorial mutagenesis enables resource-efficient engineering of CRISPR-Cas9 genome editor activities
Thean, D. G. L., Chu, H. Y., Fong, J. H. C., Chan, B. K. C., Zhou, P., Kwok, C. C. S., Chan, Y. M., & 5 others , 2022, In: Nature Communications. 13, 2219.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 2 - 2021
- Published
Defining genome-wide CRISPR–Cas genome-editing nuclease activity with GUIDE-seq
Malinin, N. L., Lee, G., Lazzarotto, C. R., Li, Y., Zheng, Z., Nguyen, N. T., Liebers, M., & 6 others , Dec 2021, In: Nature Protocols. 16, 12, p. 5592–5615Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 6 - Published
Efficacy of Loop-Mediated Isothermal Amplification for H. pylori Detection as Point-of-Care Testing by Noninvasive Sampling
Sohrabi, A., Franzen, J., Tertipis, N., Zagai, U., Li, W., Zheng, Z. & Ye, W., Sep 2021, In: Diagnostics. 11, 9, 1538.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 1 Evaluation of endocrine resistance using ESR1 genotyping of circulating tumor cells and plasma DNA
Sundaresan, T. K., Dubash, T. D., Zheng, Z., Bardia, A., Wittner, B. S., Aceto, N., Silva, E. J., & 7 others , Jul 2021, In: Breast Cancer Research and Treatment. 188, 1, p. 43-52Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 3- Published
Modified Protein And Method for Altering Genome of Cell
SHI, J., ZHENG, Z. & TAN, Y., 13 Apr 2021, Patent No. US10,975,364, Priority No. 16/552,034Research output: Patents, Agreements and Assignments (RGC: 51, 52, 53) › 51_Patents granted (CityU only, data source from KTO)
- Published
Noncanonical Gene Fusions Detected at the DNA Level Necessitate Orthogonal Diagnosis Methods Before Targeted Therapy
Song, Z., Lu, C., Xu, C. & Zheng, Z., Mar 2021, In: Journal of Thoracic Oncology. 16, 3, p. 344-348Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › Editorial Preface
Scopus citations: 5 - 2020
- Published
A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets
Zhou, P., Chan, B. K., Wan, Y. K., Yuen, C. T., Choi, G. C., Li, X., Tong, C. S., & 13 others , 11 Aug 2020, In: Cell Reports. 32, 6, 108020.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 15 - Published
Cancer-associated histone mutation H2BG53D disrupts DNA-histone octamer interaction and promotes oncogenic phenotypes
Wan, Y. C. E., Leung, T. C. S., Ding, D., Sun, X., Liu, J., Zhu, L., Kang, T. Z. E., & 13 others , 2020, In: Signal Transduction and Targeted Therapy. 5, 27.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › Letter › peer-review
Scopus citations: 11 - 2019
- Published
Rationally engineered Staphylococcus aureus Cas9 nucleases with high genome-wide specificity
Tan, Y., Chu, A. H., Bao, S., Hoang, D. A., Kebede, F. T., Xiong, W., Ji, M., & 2 others , 15 Oct 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 42, p. 20969-20976Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 50 - Published
Bone Sarcoma With EWSR1-NFATC2 Fusion: Sarcoma With Varied Morphology and Amplification of Fusion Gene Distinct From Ewing Sarcoma
Yau, D. T. W., Chan, J. K. C., Bao, S., Zheng, Z., Lau, G. T. C. & Chan, A. C. L., Aug 2019, In: International Journal of Surgical Pathology. 27, 5, p. 561–567Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 13 - Published
Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9
Choi, G. C. G., Zhou, P., Yuen, C. T. L., Chan, B. K. C., Xu, F., Bao, S., Chu, H. Y., & 5 others , Aug 2019, In: Nature Methods. 16, 8, p. 722–730Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 28 Highly Multiplexed Fluorescence in Situ Hybridization for in Situ Genomics
Onozato, M. L., Yapp, C., Richardson, D., Sundaresan, T., Chahal, V., Lee, J., Sullivan, J. P., & 11 others , May 2019, In: Journal of Molecular Diagnostics. 21, 3, p. 390-407Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 8- 2018
- Accepted/In press/Filed
Enrichment and determination of nucleic acids targets
ZHENG, Z. & KEBEDE, F. T., 7 Aug 2018, (Accepted/In press/Filed) Priority No. 16/057,004Research output: Patents, Agreements and Assignments (RGC: 51, 52, 53) › 51_Patents granted (CityU only, data source from KTO)
Artificial Intelligence Approach for Variant Reporting
Zomnir, M. G., Lipkin, L., Pacula, M., Dominguez Meneses, E., MacLeay, A., Duraisamy, S., Nadhamuni, N., & 8 others , 22 Mar 2018, In: JCO Clinical Cancer Informatics. 2, 13 p.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 13Expressed Gene Fusions as Frequent Drivers of Poor Outcomes in Hormone Receptor-Positive Breast Cancer
Matissek, K. J., Onozato, M. L., Sun, S., Zheng, Z., Schultz, A., Lee, J., Patel, K., & 27 others , Mar 2018, In: Cancer Discovery. 8, 3, p. 336-353Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 26- 2017
- Published
Unique distribution of programmed death ligand 1 (PD-L1) expression in East Asian non-small cell lung cancer
Pan, Y., Zheng, D., Li, Y., Cai, X., Zheng, Z., Jin, Y., Hu, H., & 7 others , Aug 2017, In: Journal of Thoracic Disease. 9, 8, p. 2579-2586Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 44 Recurrent and functional regulatory mutations in breast cancer
Rheinbay, E., Parasuraman, P., Grimsby, J., Tiao, G., Engreitz, J. M., Kim, J., Lawrence, M. S., & 26 others , 6 Jul 2017, In: Nature. 547, p. 55-60Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Scopus citations: 208