Dr. ZHENG Zongli (鄭宗立)

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Research Output

  1. 2020
  2. Published

    Cancer-associated histone mutation H2BG53D disrupts DNA-histone octamer interaction and promotes oncogenic phenotypes

    Wan, Y. C. E., Leung, T. C. S., Ding, D., Sun, X., Liu, J., Zhu, L., Kang, T. Z. E. & 13 others, Yang, D., Zhang, Y., Zhang, J., Qian, C., Huen, M. S. Y., Li, Q., Chow, M. Z. Y., Zheng, Z., Han, J., Goel, A., Wang, X., Ishibashi, T. & Chan, K. M., 2020, In : Signal Transduction and Targeted Therapy. 5, 27.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

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  3. 2019
  4. Published

    Rationally engineered Staphylococcus aureus Cas9 nucleases with high genome-wide specificity

    Tan, Y., Chu, A. H., Bao, S., Hoang, D. A., Kebede, F. T., Xiong, W., Ji, M. & 2 others, Shi, J. & Zheng, Z., 15 Oct 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 42, p. 20969-20976

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 6
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  5. Accepted/In press/Filed

    Modified Protein and Method for Altering Genome of Cell

    ZHENG, Z., SHI, J. & TAN, Y., 27 Aug 2019, (Accepted/In press/Filed) Priority No. 16/552,034

    Research output: Patents, Agreements and Assignments (RGC: 51, 52, 53) › 51_Patents granted (CityU only, data source from KTO)

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  6. Published

    Bone Sarcoma With EWSR1-NFATC2 Fusion: Sarcoma With Varied Morphology and Amplification of Fusion Gene Distinct From Ewing Sarcoma

    Yau, D. T. W., Chan, J. K. C., Bao, S., Zheng, Z., Lau, G. T. C. & Chan, A. C. L., Aug 2019, In : International Journal of Surgical Pathology. 27, 5, p. 561–567

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 4
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  7. Published

    Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9

    Choi, G. C. G., Zhou, P., Yuen, C. T. L., Chan, B. K. C., Xu, F., Bao, S., Chu, H. Y. & 5 others, Thean, D., Tan, K., Wong, K. H., Zheng, Z. & Wong, A. S. L., Aug 2019, In : Nature Methods. 16, 8, p. 722–730

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 4
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  8. Highly Multiplexed Fluorescence in Situ Hybridization for in Situ Genomics

    Onozato, M. L., Yapp, C., Richardson, D., Sundaresan, T., Chahal, V., Lee, J., Sullivan, J. P. & 11 others, Madden, M. W., Shim, H. S., Liebers, M., Ho, Q., Maheswaran, S., Haber, D. A., Zheng, Z., Clancy, B., Elliott, H. L., Lennerz, J. K. & Iafrate, A. J., May 2019, In : Journal of Molecular Diagnostics. 21, 3, p. 390-407

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 1
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  9. 2018
  10. Accepted/In press/Filed

    Enrichment and determination of nucleic acids targets

    ZHENG, Z. & KEBEDE, F. T., 7 Aug 2018, (Accepted/In press/Filed) Priority No. 16/057,004

    Research output: Patents, Agreements and Assignments (RGC: 51, 52, 53) › 51_Patents granted (CityU only, data source from KTO)

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  11. Artificial Intelligence Approach for Variant Reporting

    Zomnir, M. G., Lipkin, L., Pacula, M., Dominguez Meneses, E., MacLeay, A., Duraisamy, S., Nadhamuni, N. & 8 others, Al Turki, S. H., Zheng, Z., Rivera, M., Nardi, V., Dias-Santagata, D., Iafrate, A. J., Le, L. P. & Lennerz, J. K., 22 Mar 2018, In : JCO Clinical Cancer Informatics. 2, 13 p.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 3
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  12. Expressed Gene Fusions as Frequent Drivers of Poor Outcomes in Hormone Receptor-Positive Breast Cancer

    Matissek, K. J., Onozato, M. L., Sun, S., Zheng, Z., Schultz, A., Lee, J., Patel, K. & 27 others, Jerevall, P., Saladi, S. V., Macleay, A., Tavallai, M., Badovinac-Crnjevic, T., Barrios, C., Beşe, N., Chan, A., Chavarri-Guerra, Y., Debiasi, M., Demirdögen, E., Egeli, Ü., Gökgöz, S., Gomez, H., Liedke, P., Tasdelen, I., Tolunay, S., Werutsky, G., St. Louis, J., Horick, N., Finkelstein, D. M., Le, L. P., Bardia, A., Goss, P. E., Sgroi, D. C., Iafrate, A. J. & Ellisen, L. W., Mar 2018, In : Cancer Discovery. 8, 3, p. 336-353

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 10
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  13. 2017
  14. Published

    Unique distribution of programmed death ligand 1 (PD-L1) expression in East Asian non-small cell lung cancer

    Pan, Y., Zheng, D., Li, Y., Cai, X., Zheng, Z., Jin, Y., Hu, H. & 7 others, Cheng, C., Shen, L., Wang, J., Ji, H., Sun, Y., Zhou, X. & Chen, H., Aug 2017, In : Journal of Thoracic Disease. 9, 8, p. 2579-2586

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 15
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  15. Recurrent and functional regulatory mutations in breast cancer

    Rheinbay, E., Parasuraman, P., Grimsby, J., Tiao, G., Engreitz, J. M., Kim, J., Lawrence, M. S. & 26 others, Taylor-Weiner, A., Rodriguez-Cuevas, S., Rosenberg, M., Hess, J., Stewart, C., Maruvka, Y. E., Stojanov, P., Cortes, M. L., Seepo, S., Cibulskis, C., Tracy, A., Pugh, T. J., Lee, J., Zheng, Z., Ellisen, L. W., Iafrate, A. J., Boehm, J. S., Gabriel, S. B., Meyerson, M., Golub, T. R., Baselga, J., Hidalgo-Miranda, A., Shioda, T., Bernards, A., Lander, E. S. & Getz, G., 6 Jul 2017, In : Nature. 547, p. 55-60

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 120
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  16. Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor

    Alvarez-Breckenridge, C., Miller, J. J., Nayyar, N., Gill, C. M., Kaneb, A., D’Andrea, M., Le, L. P. & 18 others, Lee, J., Cheng, J., Zheng, Z., Butler, W. E., Multani, P., Chow Maneval, E., Ha Paek, S., Toyota, B. D., Dias-Santagata, D., Santagata, S., Romero, J., Shaw, A. T., Farago, A. F., Yip, S., Cahill, D. P., Batchelor, T. T., Iafrate, A. J. & Brastianos, P. K., 20 Mar 2017, In : npj Precision Oncology. 1, 5.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

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  17. 2016

  18. Severity of acute cholecystitis and risk of iatrogenic bile duct injury during cholecystectomy, a population-based case-control study

    Törnqvist, B., Waage, A., Zheng, Z., Ye, W. & Nilsson, M., 1 May 2016, In : World Journal of Surgery. 40, 5, p. 1060-1067

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 26
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  19. Met exon 14 skipping in non-small cell lung cancer

    Heist, R. S., Shim, H. S., Gingipally, S., Mino-Kenudson, M., Le, L., Gainor, J. F., Zheng, Z. & 8 others, Aryee, M., Xia, J., Jia, P., Jin, H., Zhao, Z., Pao, W., Engelman, J. A. & Iafrate, A. J., 1 Apr 2016, In : Oncologist. 21, 4, p. 481-486

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 46
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  20. Published

    High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects

    Kleinstiver, B. P., Pattanayak, V., Prew, M. S., Tsai, S. Q., Nguyen, N. T., Zheng, Z. & Joung, J. K., 28 Jan 2016, In : Nature. 529, 7587, p. 490-495

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 989
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  21. Impact of next-generation sequencing on the clinical diagnosis of pancreatic cysts

    Jones, M., ZHENG, Z., Wang, J., Dudley, J., Albanese, E., Kadayifci, A., Dias-Santagata, D. & 6 others, Le, L., Brugge, W. R., Castillo, C. F., Mino-Kenudson, M., Iafrate, A. J. & Pitman, M. B., 1 Jan 2016, In : Gastrointestinal Endoscopy. 83, 1, p. 140-148

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 71
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  22. Next-Generation Sequencing and Fluorescence in Situ Hybridization Have Comparable Performance Characteristics in the Analysis of Pancreaticobiliary Brushings for Malignancy

    Dudley, J. C., ZHENG, Z., McDonald, T., Le, L. P., Dias-Santagata, D., Borger, D., Batten, J. & 7 others, Vernovsky, K., Sweeney, B., Arpin, R. N., Brugge, W. R., Forcione, D. G., Pitman, M. B. & Iafrate, A. J., 1 Jan 2016, In : Journal of Molecular Diagnostics. 18, 1, p. 124-130

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 30
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  23. 2015

  24. Durable Clinical Response to Entrectinib in NTRK1-Rearranged Non-Small Cell Lung Cancer

    Farago, A. F., Le, L. P., Zheng, Z., Muzikansky, A., Drilon, A., Patel, M., Bauer, T. M. & 12 others, Liu, S. V., Ou, S. I., Jackman, D., Costa, D. B., Multani, P. S., Li, G. G., Hornby, Z., Chow-Maneval, E., Luo, D., Lim, J. E., Iafrate, A. J. & Shaw, A. T., 1 Dec 2015, In : Journal of Thoracic Oncology. 10, 12, p. 1670-1674

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 111
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  25. Published

    Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition

    Kleinstiver, B. P., Prew, M. S., Tsai, S. Q., Nguyen, N. T., Topkar, V. V., Zheng, Z. & Joung, J. K., Dec 2015, In : Nature Biotechnology. 33, 12, p. 1293-1298

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 250
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  26. Identification of insertions in PTEN and TP53 in anaplastic thyroid carcinoma with angiogenic brain metastasis

    Sadow, P. M., Dias-Santagata, D., Zheng, Z., Lin, D. T., Le, L. P. & Nucera, C., Dec 2015, In : Endocrine-Related Cancer. 22, 6, p. L23-L28

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal

    Scopus citations: 4
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