Prof. HUANG Yu (黃聿)

Research Output

  1. 2022
  2. Online published

    Kidney tubular transcription co-activator, Yes-associated protein 1 (YAP), controls the expression of collecting duct aquaporins and water homeostasis

    Zhang, Y., Huang, H., Kong, Y., Xu, C., Dai, L., Geng, X., Deng, Y., & 15 othersWang, Y., Liu, Y., Meng, C., Zhang, X., Li, J., Qin, J., Feng, B., Mak, K. K., Wang, L., Huang, Y., Wang, W., Lan, H., Yang, B., Lu, H. A. J. & Xia, Y., 1 Nov 2022, (Online published) In: Kidney International. 13 p.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 1
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  3. Published

    Endothelial UCP2 Is a Mechanosensitive Suppressor of Atherosclerosis

    Luo, J., Cheng, C. K., He, L., Pu, Y., Zhang, Y., Lin, X., Xu, A., & 5 othersLau, C. W., Tian, X. Y., Ma, R. C. W., Jo, H. & Huang, Y., 19 Aug 2022, In: Circulation Research. 131, 5, p. 424-441

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 2
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  4. Published

    Targeting PDE4B (Phosphodiesterase-4 Subtype B) for Cardioprotection in Acute Myocardial Infarction via Neutrophils and Microcirculation

    Wan, Q., Xu, C., Zhu, L., Zhang, Y., Peng, Z., Chen, H., Rao, H., & 11 othersZhang, E., Wang, H., Chu, F., Ning, X., Yang, X., Yuan, J., Wu, Y., Huang, Y., Hu, S., Liu, D. & Wang, M., 19 Aug 2022, In: Circulation Research. 131, 5, p. 442-455

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 1
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  5. Berberine Reverses Nitroglycerin Tolerance through Suppressing Protein Kinase C Alpha Activity in Vascular Smooth Muscle Cells

    Zhang, H., Dong, J., Lau, C. & Huang, Y., Aug 2022, In: Cardiovascular Drugs and Therapy. 36, 4, p. 633–643

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 3
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  6. Published

    Nonalbuminuric Diabetic Kidney Disease and Risk of All-Cause Mortality and Cardiovascular and Kidney Outcomes in Type 2 Diabetes: Findings From the Hong Kong Diabetes Biobank

    Jin, Q., Luk, A. O., Lau, E. S., Tam, C. H., Ozaki, R., Lim, C. K., Wu, H., & 28 othersJiang, G., Chow, E. Y. K., Ng, J. K., Kong, A. P. S., Fan, B., Lee, K. F., Siu, S. C., Hui, G., Tsang, C. C., Lau, K. P., Leung, J. Y., Tsang, M., Kam, G., Lau, I. T., Li, J. K., Yeung, V. T., Lau, E., Lo, S., Fung, S., Cheng, Y. L., Chow, C. C., Huang, Y., Lan, H., Szeto, C. C., So, W. Y., Chan, J. C. N., Ma, R. C. W. & on behalf of the Hong Kong Diabetes Biobank Study Group, O. B. O. T. H. K. D. B. S. G., Aug 2022, In: American Journal of Kidney Diseases. 80, 2, p. 196-206.e1

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 4
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  7. Published

    Endothelial shear stress signal transduction and atherogenesis: From mechanisms to therapeutics

    He, L., Zhang, C., Chen, Q., Wang, L. & Huang, Y., Jul 2022, In: Pharmacology and Therapeutics. 235, 108152.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 7
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  8. Published

    Follistatin-like 1 (FSTL1) interacts with Wnt ligands and Frizzled receptors to enhance Wnt/β-catenin signaling in obstructed kidneys in vivo

    Zhang, Y., Wang, Y., Zheng, G., Liu, Y., Li, J., Huang, H., Xu, C., & 13 othersZeng, Y., Zhang, X., Qin, J., Dai, C., Hambrock, H. O., Hartmann, U., Feng, B., Mak, K. K., Liu, Y., Lan, H., Huang, Y., Zheng, Z. & Xia, Y., Jul 2022, In: Journal of Biological Chemistry. 298, 7, 102010.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 3
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  9. Published

    Targeting endothelial dysfunction and inflammation

    Wang, L., Cheng, C. K., Yi, M., Lui, K. O. & Huang, Y., Jul 2022, In: Journal of Molecular and Cellular Cardiology. 168, p. 58-67

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 5
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  10. Published

    Activation of AMPK/miR-181b Axis Alleviates Endothelial Dysfunction and Vascular Inflammation in Diabetic Mice

    Cheng, C., Shang, W., Liu, J., Cheang, W., Wang, Y., Xiang, L., Lau, C., & 4 othersLuo, J., Ng, C., Huang, Y. & Wang, L., Jun 2022, In: Antioxidants. 11, 6, 1137.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 2
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  11. Published

    Branched-chain amino acid supplementation impairs insulin sensitivity and promotes lipogenesis during exercise in diet-induced obese mice

    Zhang, H., Xiang, L., Huo, M., Wu, Y., Yu, M., Lau, C. W., Tian, D., & 10 othersGou, L., Huang, Y., Luo, J., Wang, L., Song, W., Huang, J., Cai, Z., Chen, S., Tian, X. Y. & Huang, Y., Jun 2022, In: Obesity. 30, 6, p. 1205-1218

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 1
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  12. Published

    Muscle satellite cells are impaired in type 2 diabetic mice by elevated extracellular adenosine

    Han, L., Wang, G., Zhou, S., Situ, C., He, Z., Li, Y., Qiu, Y., & 6 othersHuang, Y., Xu, A., Ong, M. T. Y., Wang, H., Zhang, J. & Wu, Z., 31 May 2022, In: Cell Reports. 39, 9, 110884.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 1
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  13. Published

    Restoration of Autophagic Flux Improves Endothelial Function in Diabetes Through Lowering Mitochondrial ROS-Mediated eNOS Monomerization

    Zhao, L., Zhang, C., He, L., Chen, Q., Liu, L., Kang, L., Liu, J., & 10 othersLuo, J., Gou, L., Qu, D., Song, W., Lau, C. W., Ko, H., Mok, V. C. T., Tian, X. Y., Wang, L. & Huang, Y., May 2022, In: Diabetes. 71, 5, p. 1099-1114

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 4
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  14. Published

    A human pluripotent stem cell-based model of SARS-CoV-2 infection reveals an ACE2-independent inflammatory activation of vascular endothelial cells through TLR4

    Ma, Z., Li, X., Fan, R. L., Yang, K. Y., Ng, C. S., Lau, R. W., Wong, R. H., & 10 othersNg, K. K., Wang, C. C., Ye, P., Fu, Z., Chin, A. W. H., Lai, M. Y. A., Huang, Y., Tian, X. Y., Poon, L. L. M. & Lui, K. O., 8 Mar 2022, In: Stem Cell Reports. 17, 3, p. 538-555

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 5
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  15. Online published

    SOX4 is a novel phenotypic regulator of endothelial cells in atherosclerosis revealed by single-cell analysis

    Cheng, C. K., Lin, X., Pu, Y., Tse, J. K. Y., Wang, Y., Zhang, C., Cao, X., & 13 othersLau, C. W., Huang, J., He, L., Luo, J., Shih, Y., Wan, S., Ng, C. F., Wang, L., Ma, R. C. W., Chiu, J., Chan, T. F., Yu Tian, X. & Huang, Y., 1 Mar 2022, (Online published) In: Journal of Advanced Research.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 2
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  16. Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients With Type 2 Diabetes

    Jiang, G., Luk, A. O., Tam, C. H., Ozaki, R., Lim, C. K., Chow, E. Y., Lau, E. S., & 28 othersKong, A. P. S., Fan, B., Hong Kong Diabetes Register TRS Study Group, including, H. K. D. R. T. S. G. I., Lee, K. F., Siu, S. C., Hui, G., Tsang, C. C., Lau, K. P., Leung, J. Y., Tsang, M., Kam, G., Lau, I. T., Li, J. K., Yeung, V. T., Lau, E., Lo, S., Fung, S., Cheng, Y. L., Chow, C. C., Hong Kong Diabetes Biobank Study Group, including, H. K. D. B. S. G. I., Tang, N. L. S., Huang, Y., Lan, H., Oram, R. A., Szeto, C. C., So, W. Y., Chan, J. C. N. & Ma, R. C. W., Mar 2022, In: Diabetes. 71, 3, p. 520-529

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 3
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  17. Published

    Endothelial contribution to COVID-19: an update on mechanisms and therapeutic implications

    Ma, Z., Yang, K. Y., Huang, Y. & Lui, K. O., Mar 2022, In: Journal of Molecular and Cellular Cardiology. 164, p. 69-82

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 16
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  18. Published

    ORP4L is a prerequisite for the induction of T-cell leukemogenesis associated with human T-cell leukemia virus 1

    Zhong, W., Cao, X., Pan, G., Niu, Q., Feng, X., Xu, M., Li, M., & 3 othersHuang, Y., Yi, Q. & Yan, D., 17 Feb 2022, In: Blood. 139, 7, p. 1052-1065

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 4
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  19. Published

    Myogenic Vasoconstriction Requires Canonical Gq/11 Signaling of the Angiotensin II Type 1 Receptor

    Cui, Y., Kassmann, M., Nickel, S., Zhang, C., Alenina, N., Anistan, Y. M., Schleifenbaum, J., & 4 othersBader, M., Welsh, D. G., Huang, Y. & Gollasch, M., 15 Feb 2022, In: Journal of the American Heart Association. 11, 4, e022070.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 3
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  20. Endothelial dysfunction after androgen deprivation therapy and the possible underlying mechanisms

    Teoh, J. Y., Tian, X., Wong, C. Y., Lau, C., Cheng, C., Tang, V. W., Chan, R. C., & 2 othersHuang, Y. & Ng, C., 1 Jan 2022, In: Prostate. 82, 1, p. 13-25

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 2
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  21. Endothelial PPARδ facilitates the post-ischemic vascular repair through interaction with HIF1α

    Wu, Y., Tang, X., Lee, S., Hong, H., Cao, X., Wai Lau, C., Liu, B., & 5 othersChawla, A., Ma, R. C. W., Huang, Y., Lui, K. O. & Tian, X. Y., 2022, In: Theranostics. 12, 4, p. 1855-1869

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 2
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