Personal profile
Author IDs
ORCID iD: 0000-0003-3683-9695
Scopus Author ID: 55138932900
Impact
Research Interests/Areas
- Brain target for chronic pain−central nervous system sensitization and synaptic plasticity
- Emotional disorders and cognitive deficits; Learning and memory
- Theta rhythms and synchronization within anterior cingulate cortex circuitry during aversive pain learning and retrieval
- Sensory signal transduction in the vagal primary afferent neurons, and the role of vagus nerve in the modulation of pain
- Pre-clinical animal disease models are used in our laboratory, e.g. Visceral hypersensitivity; Oral-facial pain; Early life Stress (maternal separation); Chronic Pancreatitis; Neurotoxic Action of Ciguatoxin; Chemotherapy induced Emesis and cognitive disorders
Services outside CityUHK
- Fellow, American Gastroenterological Association (Since 2006)
- Honorary Professor, Faculty of Dentistry, The University of Hong Kong
- Honorary Professor, Medical School, Beijing University
- Guest PI, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
Related Links
Education/Academic qualification
Postdoc Fellow, Department Hypertension, University of Michigan
1988 → 1991
Postdoc Fellow, Department of Oral and maxillofacial Surgery, Faculty of Dentistry, University of Michigan
1986 → 1987
MD, Beijing Medical University
1962 → 1968
FAGA (US)
Experiences and Professional Affiliations
Department of Biomedical Sciences (previous Biology & Chemistry), City University of Hong Kong
Dec 2009 → …
Research Associate Professor, Gastroenterology Department of Internal Medicine, University of Michigan Medical School
2002
Assistant Research Scientist, Gastroenterology Department of Internal Medicine, University of Michigan Medical School
1997
Research Associate, Gastroenterology Department of Internal Medicine, University of Michigan
1992 → 1996
Oral-Maxillofacial Surgeon, Nanjing Medical School
1978 → 1985
General surgeon at the Qinghai, Nanjing Medical School
1969 → 1978
Deputy director, Center of Biosystem, Neuroscience and Nanotechnology, City University of Hong Kong
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 6 Clean Water and Sanitation -
SDG 14 Life Below Water
Fingerprint
- 1 Similar Profiles
Collaborations from the last five years
Research output
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Astrocytic GPCR signaling in the anterior cingulate cortex modulates decision making in rats
Akter, M., Fu, Z., Zheng, X., Iqbal, Z., Zhang, N., Karim, A. & Li, Y., 2024, In: Oxford Open Neuroscience. 3, kvae010.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile35 Downloads (CityUHK Scholars) -
Does astrocytic L-lactate enhance cognition through myelination?
Akter, M. & Li, Y., Jun 2024, In: Neural Regeneration Research. 19, 6, p. 1167-1168 2 p.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile67 Downloads (CityUHK Scholars) -
Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats
Iqbal, Z., Lei, Z., Ramkrishnan, A. S., Liu, S., Hasan, M., Akter, M., Lam, Y. Y. & Li, Y., 2023, In: Communications Biology. 6, 1, 10.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile25 Link opens in a new tab Citations (Scopus)95 Downloads (CityUHK Scholars) -
Astrocyte and L-lactate in the anterior cingulate cortex modulate schema memory and neuronal mitochondrial biogenesis
Akter, M., Hasan, M., Ramkrishnan, A. S., Iqbal, Z., Zheng, X., Fu, Z., Lei, Z., Karim, A. & Li, Y., 2023, In: eLife. 12, 27 p., e85751.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile13 Link opens in a new tab Citations (Scopus)46 Downloads (CityUHK Scholars) -
Astrocyte L-Lactate Signaling in the ACC Regulates Visceral Pain Aversive Memory in Rats
Iqbal, Z., Liu, S., Lei, Z., Ramkrishnan, A. S., Akter, M. & Li, Y., Jan 2023, In: Cells. 12, 1, 21 p., 26.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile18 Link opens in a new tab Citations (Scopus)85 Downloads (CityUHK Scholars)
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ITF-InnoHK-ExtU-Lead: Immune and Metabolic Regulations for Neurodegeneration Disease
LI, Y. (Principal Investigator / Project Coordinator)
30/09/25 → …
Project: Research
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GRF: Astrocyte Adrenergic Signaling in the Anterior Cingulate Cortex Contributes to Visceral Pain-Evoked Aversion in Rats
LI, Y. (Principal Investigator / Project Coordinator) & Wang, L. (Co-Investigator)
1/01/22 → …
Project: Research
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ITF-InnoHK-ExtU-Lead: Large-scale Neural Oscillations Play a Primary Role in Fundamental Cognitive Functions
LI, Y. (Principal Investigator / Project Coordinator), CHAN, H. M. (Co-Investigator), LAU, C. (Co-Investigator), LEE, Y. (Co-Investigator) & Pan, G. (Co-Investigator)
5/09/20 → …
Project: Research
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OTHERS-SRI: 前扣带回皮层星形胶质细胞的乳酸信号调控“图式学习记忆”及新信息之快速吸收
LI, Y. (Principal Investigator / Project Coordinator)
1/01/20 → …
Project: Research
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GRF: Chronic Pain Induces Hypomyelination: A Causal Mechanism for Brain Circuitry Desynchronization and Impaired Decision Making.
LI, Y. (Principal Investigator / Project Coordinator) & Wang, L. (Co-Investigator)
1/01/21 → 25/06/25
Project: Research
Press/Media
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New brain studies for treating myelin-related diseases
11/12/19 → 17/12/19
8 items of Media coverage
Press/Media: Press / Media
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Discovering the Neural Mechanisms Between Chronic Pain and Cognitive Deficits
3/05/21
1 item of Media coverage
Press/Media: Press / Media
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Secret to improving decision-making revealed
CHAN, H. M., LI, Y., WANG, J. & RAMKRISHNAN, A. S.
6/09/18
1 item of Media coverage
Press/Media: Press / Media
Activities
- 1 RGC 61 - Journal editor
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中華臨床醫師雜誌(電子版) (Journal)
LI, Y. (Editor)
2012Activity: Publication peer-review and editorial work (RGC: 61) › RGC 61 - Journal editor