Personal profile
Author IDs
ORCID iD: 0000-0001-9639-1584
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations from the last five years
Research output
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DDintensity: Addressing imbalanced drug-drug interaction risk levels using pre-trained deep learning model embeddings
Xie, W., Chen, X., Huang, L., Zheng, Z., Wang, Y., Zhang, R., Zhang, X., Liu, Z., Peng, C., Gullerova, M. & Wong, K.-C., Oct 2025, In: Artificial Intelligence in Medicine. 168, 103202.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
2 Link opens in a new tab Citations (Scopus) -
scOTM: A Deep Learning Framework for Predicting Single-Cell Perturbation Responses with Large Language Models
Wang, Y. (Co-first Author), Lu, T. (Co-first Author), Chen, X., Yao, Z. & Wong, K.-C., Aug 2025, In: Bioengineering. 12, 8, 884.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile33 Downloads (CityUHK Scholars) -
scPER2P: Parameter-Efficient Single-Cell LLM for Translated Proteome Profiles
Wang, Y., Chen, X., Zheng, Z., Xie, W., Wang, F., Huang, L. & Wong, K. C., 2025, Neural Information Processing: 31st International Conference, ICONIP 2024, Auckland, New Zealand, December 2–6, 2024, Proceedings, Part V. Mahmud, M., Doborjeh, M., Wong, K., Leung, A. C. S., Doborjeh, Z. & Tanveer, M. (eds.). Singapore: Springer , p. 1-15 (Lecture Notes in Computer Science; vol. 15290).Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review
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A dual diffusion model enables 3D molecule generation and lead optimization based on target pockets
Huang, L., Xu, T., Yu, Y., Zhao, P., Chen, X., Han, J., Xie, Z., Li, H., Zhong, W., Wong, K.-C. & Zhang, H., 2024, In: Nature Communications. 15, 2657.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile103 Link opens in a new tab Citations (Scopus)58 Downloads (CityUHK Scholars) -
DeepSeq2Drug: An expandable ensemble end-to-end anti-viral drug repurposing benchmark framework by multi-modal embeddings and transfer learning
Xie, W., Yu, J., Huang, L., For, L. S., Zheng, Z., Chen, X., Wang, Y., Liu, Z., Peng, C. & Wong, K.-C., Jun 2024, In: Computers in Biology and Medicine. 175, 108487.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
7 Link opens in a new tab Citations (Scopus)
Prizes
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Outstanding Academic Performance Award for Research Degree Students (non-local UGC-funded students)
CHEN, X. (Recipient), 16 Aug 2022
Prize: RGC 64B - Prizes and awards
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Outstanding Academic Performance Award for Research Degree Students (non-local UGC-funded students)
CHEN, X. (Recipient), 16 Aug 2021
Prize: RGC 64B - Prizes and awards
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Thesis
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Deep Learning in Metagenomics and Spatial Transcriptomics: Phenotype and Gene Inference
CHEN, X. (Author), WONG, K. C. (Supervisor), 18 Sept 2023Student thesis: Doctoral Thesis