Dr. XIONG Wenjun (熊文君)

Research Output

  1. 2021
  2. Accepted/In press/Filed

    Drug And GEne Therapy to Treat High Myopia And Other Ocular Disorders with Enlarged Eye Globes

    MAI, S. & XIONG, W., 11 Jun 2021, (Accepted/In press/Filed) Priority No. 17/346,036

    Research output: Patents, Agreements and Assignments (RGC: 51, 52, 53)51_Patents granted (CityU only, data source from KTO)

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  3. Published

    Nrf2 overexpression rescues the RPE in mouse models of retinitis pigmentosa

    Wu, D. M., Ji, X., Ivanchenko, M. V., Chung, M., Piper, M., Rana, P., Wang, S. K. & 7 others, Xue, Y., West, E., Zhao, S. R., Xu, H., Cicconet, M., Xiong, W. & Cepko, C. L., 25 Jan 2021, In: JCI insight. 6, 2, e145029.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 3
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  4. 2020
  5. Published

    Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice

    Feng, T., Mai, S., Roscoe, J. M., Sheng, R. R., Ullah, M., Zhang, J., Katz, I. I. & 3 others, Yu, H., Xiong, W. & Hu, F., 5 Oct 2020, In: EMBO Reports. 21, 10, e50219.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 11
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  6. 2019
  7. Published

    Rationally engineered Staphylococcus aureus Cas9 nucleases with high genome-wide specificity

    Tan, Y., Chu, A. H., Bao, S., Hoang, D. A., Kebede, F. T., Xiong, W., Ji, M. & 2 others, Shi, J. & Zheng, Z., 15 Oct 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 42, p. 20969-20976

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 25
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  8. Published

    Antagonistic interactions of Srebp2 and Lrp2 in controlling mouse eye size

    Mai, S., Wu, D. M. & Xiong, W., 2 May 2019.

    Research output: Conference Papers (RGC: 31A, 31B, 32, 33)32_Refereed conference paper (no ISBN/ISSN)peer-review

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  9. Published

    AAV-CRISPR/Cas9-Mediated Gene Knock-In Therapy to Rescue Photoreceptor Degeneration in the P23H Rhodopsin Mutant Mice

    Hoang, D. A., Zhang, H., Zhang, H. & Xiong, W., Apr 2019.

    Research output: Conference Papers (RGC: 31A, 31B, 32, 33)32_Refereed conference paper (no ISBN/ISSN)peer-review

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  10. Published

    Author Correction: Gene and mutation independent therapy via CRISPR-Cas9 mediated cellular reprogramming in rod photoreceptors

    Zhu, J., Ming, C., Fu, X., Duan, Y., Hoang, D. A., Rutgard, J., Zhang, R. & 8 others, Wang, W., Hou, R., Zhang, D., Zhang, E., Zhang, C., Hao, X., Xiong, W. & Zhang, K., Apr 2019, In: Cell Research. 29, 4, p. 337

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)Erratumpeer-review

    Scopus citations: 2
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  11. Published

    Overexpression of Nrf2 in the retinal pigment epithelium of rd1 mice improves RPE morphology

    Wu, D. M., Ivanchenko, M., Ji, X., Xu, H., Zhao, S. R., XIONG, W. & Cepko, C. L., Apr 2019.

    Research output: Conference Papers (RGC: 31A, 31B, 32, 33)32_Refereed conference paper (no ISBN/ISSN)peer-review

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  12. Published

    AAV cis-regulatory sequences are correlated with ocular toxicity

    Xiong, W., Wu, D. M., Xue, Y., Wang, S. K., Chung, M. J., Ji, X., Rana, P. & 3 others, Zhao, S. R., Mai, S. & Cepko, C. L., 19 Mar 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 12, p. 5785-5794

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 65
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  13. Published

    Author Correction: In vivo transduction of ETV2 improves cardiac function and induces vascular regeneration following myocardial infarction

    Lee, S., Lee, D. H., Park, B., Kim, R. Y., Hoang, A. D., Woo, S., Xiong, W. & 3 others, Lee, Y. J., Ban, K. & Park, H., 2019, In: Experimental and Molecular Medicine. 51, 101.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)Erratum

    Scopus citations: 1
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  14. Published

    In vivo transduction of ETV2 improves cardiac function and induces vascular regeneration following myocardial infarction

    Lee, S., Lee, D. H., Park, B., Kim, R. Y., Hoang, A. D., Woo, S., Xiong, W. & 3 others, Lee, Y. J., Ban, K. & Park, H., 2019, In: Experimental and Molecular Medicine. 51, 13.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 6
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  15. 2018
  16. Published

    AAV-mediated overexpression of nuclear SREBP1/2 induces buphthalmos and retinal degeneration in mice

    MAI, S., Wu, D. M., Kizhatil, K., John, S. W., Cepko, C. L. & Xiong, W., Apr 2018.

    Research output: Conference Papers (RGC: 31A, 31B, 32, 33)Poster

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  17. Published

    In vivo functional imaging of retinal neurons using red and green fluorescent calcium indicators

    Cheong, S. K., Xiong, W., Strazzeri, J. M., Cepko, C. L., Williams, D. R. & Merigan, W. H., 2018, Retinal Degenerative Diseases: Mechanisms and Experimental Therapy. Springer International Publishing AG, p. 135-144 (Advances in Experimental Medicine and Biology; vol. 1074).

    Research output: Chapters, Conference Papers, Creative and Literary Works (RGC: 12, 32, 41, 45)12_Chapter in an edited book (Author)peer-review

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  18. 2017
  19. Published

    Gene and mutation independent therapy via CRISPR-Cas9 mediated cellular reprogramming in rod photoreceptors

    Zhu, J., Ming, C., Fu, X., Duan, Y., HOANG, D. A., Rutgard, J., Zhang, R. & 9 others, Wang, W., Hou, R., Zhang, D., Zhang, E., Zhang, C., Eye Gene Therapy Consortium, E. G. T. C., Hao, X., Xiong, W. & Zhang, K., Jun 2017, In: Cell Research. 27, 6, p. 830-833

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 34
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  20. Published

    Overexpression of human Nrf2 rescues cone photoreceptors and retinal pigment epithelial cells from degeneration in the rd1 mouse

    Wu, D. M., Ji, X. J., Halfer, B. P., Xue, Y., Zhao, S., Rana, P., Xiong, W. & 1 others, Cepko, C., 10 May 2017.

    Research output: Conference Papers (RGC: 31A, 31B, 32, 33)32_Refereed conference paper (no ISBN/ISSN)peer-review

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  21. 2016
  22. Distinct Expression Patterns of AAV8 Vectors with Broadly Active Promoters from Subretinal Injections of Neonatal Mouse Eyes at Two Different Ages

    Xiong, W. & Cepko, C., Oct 2016, Retinal Degenerative Diseases: Mechanisms and Experimental Therapy. Rickman, C. B., LaVail, M. M., Anderson, R. E., Grimm, C., Hollyfield, J. & Ash, J. (eds.). Springer, Cham, p. 501-7 67. (Advances in Experimental Medicine and Biology; vol. AEMB 854).

    Research output: Chapters, Conference Papers, Creative and Literary Works (RGC: 12, 32, 41, 45)12_Chapter in an edited book (Author)

    Scopus citations: 6
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  23. Published

    Overexpression of Nrf2 in the eye protects retinal pigment epithelial cells of Rd1 mice

    Wu, D. M., Ji, X., XIONG, W. & Cepko, C. L., Sep 2016, In: Investigative Ophthalmology and Visual Science. 57, 12

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)Meeting abstractpeer-review

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  24. Published

    Retinal axon guidance requires integration of eya and the Jak/Stat pathway into phosphotyrosine-based signaling circuitries in drosophila

    Hoi, C. S. L., Xiong, W. & Rebay, I., 16 May 2016, In: Genetics. 203, 3, p. 1283-1295

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 5
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  25. 2015
  26. NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage

    Xiong, W., MacColl Garfinkel, A. E., Li, Y., Benowitz, L. I. & Cepko, C. L., Apr 2015, In: Journal of Clinical Investigation. 125, 4, p. 1433-45 13 p.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 150
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  27. 2013
  28. The Abelson tyrosine kinase regulates Notch endocytosis and signaling to maintain neuronal cell fate in Drosophila photoreceptors

    Xiong, W., Morillo, S. A. & Rebay, I., 1 Jan 2013, In: Development (Cambridge). 140, 1, p. 176-184

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 10
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