Dr. CHIN Rebecca Y M (錢玥明)

Research Output

  1. 2021
  2. Published

    ANLN Enhances Triple-Negative Breast Cancer Stemness Through TWIST1 and BMP2 and Promotes its Spheroid Growth

    Maryam, A. & Chin, Y. R., Jul 2021, In: Frontiers in Molecular Biosciences. 8, 700973.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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  3. Published

    Subtype-dependent heterogeneity of super-enhancers in breast cancer

    Huang, H., Hu, J., Wang, X. & Chin, R., 21 Jun 2021.

    Research output: Conference Papers (RGC: 31A, 31B, 32, 33)Posterpeer-review

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  4. Published

    Clustering of super-enhancers for characterizing subtype identity in breast cancer

    Huang, H., Hu, J., Maryam, A., Wang, X. & Chin, R., 19 May 2021.

    Research output: Conference Papers (RGC: 31A, 31B, 32, 33)Abstractpeer-review

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  5. Published

    Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling

    Huang, H., Hu, J., Maryam, A., Huang, Q., Zhang, Y., Ramakrishnan, S., Li, J. & 10 others, Ma, H., Ma, V. W. S., Cheuk, W., So, G. Y. K., Wang, W., Cho, W. C. S., Zhang, L., Chan, K. M., Wang, X. & Chin, Y. R., 2021, In: Nature Communications. 12, 2242.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 4
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  6. 2020
  7. Published

    FOXC1 expression is associated with a triple-negative basal-like phenotype in breast cancer

    Cho, W. C. S., Ma, V. W. S., CHEUK, W., So, G. Y. K. & Chin, R. Y. M., Jun 2020.

    Research output: Conference Papers (RGC: 31A, 31B, 32, 33)Abstractpeer-review

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  8. 2019
  9. Published

    Targeting Akt isoform-specific signaling in breast cancer progression

    Tsang, T. & Chin, R., 15 Mar 2019.

    Research output: Conference Papers (RGC: 31A, 31B, 32, 33)Posterpeer-review

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  10. 2018
  11. Accepted/In press/Filed

    Guide RNA molecule and method dfor treating cancer

    CHIN, R. Y. M., WANG, X. & HU, J., 28 Sep 2018, (Accepted/In press/Filed) Priority No. 16/145,616

    Research output: Patents, Agreements and Assignments (RGC: 51, 52, 53)51_Patents granted (CityU only, data source from KTO)

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  12. Published

    Resistance mechanisms to Akt inhibitors in breast cancer

    Chin, R. Y. M., May 2018.

    Research output: Conference Papers (RGC: 31A, 31B, 32, 33)Abstractpeer-review

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  13. 2016
  14. Upregulation of AKT3 confers resistance to the AKT Inhibitor MK2206 in breast cancer

    Stottrup, C., Tsang, T. & Chin, Y. R., 1 Aug 2016, In: Molecular Cancer Therapeutics. 15, 8, p. 1964-1974

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 30
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  15. Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt

    Zhang, J., Xu, K., Liu, P., Geng, Y., Wang, B., Gan, W., Guo, J. & 8 others, Wu, F., Chin, Y. R., Berrios, C., Lien, E. C., Toker, A., DeCaprio, J. A., Sicinski, P. & Wei, W., 16 Jun 2016, In: Molecular Cell. 62, 6, p. 929-942

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 57
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  16. 2015
  17. Ptdins(3,4,5) P3 -dependent activation of the mTORC2 kinase complex

    Liu, P., Gan, W., Chin, Y. R., Ogura, K., Guo, J., Zhang, J., Wang, B. & 5 others, Blenis, J., Cantley, L. C., Toker, A., Su, B. & Wei, W., Nov 2015, In: Cancer Discovery. 5, 11, p. 1194-1209

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 189
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  18. 2014
  19. PTEN-deficient tumors depend on AKT2 for maintenance and survival

    Chin, Y. R., Yuan, X., Balk, S. P. & Toker, A., Aug 2014, In: Cancer Discovery. 4, 8, p. 942-955

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 58
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  20. Akt-ing Up on SRPK1: Oncogene or Tumor Suppressor?

    Toker, A. & Chin, Y. R., 8 May 2014, In: Molecular Cell. 54, 3, p. 329-330

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)62_Review of books or of software (or similar publications/items)peer-review

    Scopus citations: 13
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  21. Targeting Akt3 signaling in triple-negative breast cancer

    Chin, Y. R., Yoshida, T., Marusyk, A., Beck, A. H., Polyak, K. & Toker, A., 1 Feb 2014, In: Cancer Research. 74, 3, p. 964-973

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 93
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  22. 2013
  23. RhoB differentially controls akt function in tumor cells and stromal endothelial cells during breast tumorigenesis

    Kazerounian, S., Gerald, D., Huang, M., Chin, Y. R., Udayakumar, D., Zheng, N., O'Donnell, R. K. & 13 others, Perruzzi, C., Mangiante, L., Pourat, J., Phung, T. L., Bravo-Nuevo, A., Shechter, S., McNamara, S., DuHadaway, J. B., Kocher, O. N., Brown, L. F., Toker, A., Prendergast, G. C. & Benjamin, L. E., 1 Jan 2013, In: Cancer Research. 73, 1, p. 50-61

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 29
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  24. 2012
  25. Acetylation-dependent regulation of Skp2 function

    Inuzuka, H., Gao, D., Finley, L. W., Yang, W., Wan, L., Fukushima, H., Chin, Y. R. & 11 others, Zhai, B., Shaik, S., Lau, A. W., Wang, Z., Gygi, S. P., Nakayama, K., Teruya-Feldstein, J., Toker, A., Haigis, M. C., Pandolfi, P. P. & Wei, W., 6 Jul 2012, In: Cell. 150, 1, p. 179-193

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 134
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  26. 2011
  27. NFAT promotes carcinoma invasive migration through glypican-6

    Yiu, G. K., Kaunisto, A., Chin, Y. R. & Toker, A., 15 Nov 2011, In: Biochemical Journal. 440, 1, p. 157-166

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 67
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  28. MTOR drives its own activation via SCF βTrCP-dependent degradation of the mTOR inhibitor DEPTOR

    Gao, D., Inuzuka, H., Tan, M. M., Fukushima, H., Locasale, J. W., Liu, P., Wan, L. & 10 others, Zhai, B., Chin, Y. R., Shaik, S., Lyssiotis, C. A., Gygi, S. P., Toker, A., Cantley, L. C., Asara, J. M., Harper, J. W. & Wei, W., 21 Oct 2011, In: Molecular Cell. 44, 2, p. 290-303

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 173
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  29. Akt isoform-specific signaling in breast cancer: Uncovering an anti-migratory role for palladin.

    Chin, Y. R. & Toker, A., May 2011, In: Cell adhesion & migration. 5, 3, p. 211-214

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)62_Review of books or of software (or similar publications/items)peer-review

    Scopus citations: 63
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  30. 2010
  31. Akt2 regulates expression of the actin-bundling protein palladin

    Chin, Y. R. & Toker, A., 1 Dec 2010, In: FEBS Letters. 584, 23, p. 4769-4774

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 26
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