Dr. UMAR Mubarak Ishaq

Development of RNA G-quadruplex (rG4)-targeting l-RNA aptamers by rG4-SELEX

Umar, M. I., Chan, C. & Kwok, C. K., 20 Apr 2022, (Online published) In: Nature Protocols.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Scopus citations: 11

High-throughput characterization of the role of non-B DNA motifs on promoter function

Georgakopoulos-Soares, I., Victorino, J., Parada, G. E., Agarwal, V., Zhao, J., Wong, H. Y., Umar, M. I., & 8 othersElor, O., Muhwezi, A., An, J., Sanders, S. J., Kwok, C. K., Inoue, F., Hemberg, M. & Ahituv, N., 13 Apr 2022, In: Cell Genomics. 2, 4, 100111.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Scopus citations: 20

G-quadruplex RNA motifs influence gene expression in the malaria parasite Plasmodium falciparum

Dumetz, F., Chow, E. Y., Harris, L. M., Liew, S. W., Jensen, A., Umar, M. I., Chung, B., & 3 othersChan, T. F., Merrick, C. J. & Kwok, C. K., 2 Dec 2021, In: Nucleic Acids Research. 49, 21, p. 12486-12501

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Scopus citations: 11

Translational control by DHX36 binding to 5′UTR G-quadruplex is essential for muscle stem-cell regenerative functions

Chen, X., Yuan, J., Xue, G., Campanario, S., Wang, D., Wang, W., Mou, X., & 17 othersLiew, S. W., Umar, M. I., Isern, J., Zhao, Y., He, L., Li, Y., Mann, C. J., Yu, X., Wang, L., Perdiguero, E., Chen, W., Xue, Y., Nagamine, Y., Kwok, C. K., Sun, H., Muñoz-Cánoves, P. & Wang, H., 2021, In: Nature Communications. 12, 5043.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Scopus citations: 32

Specific suppression of D-RNA G-quadruplex-protein interaction with an L-RNA aptamer

Umar, M. I. & Kwok, C. K., 9 Oct 2020, In: Nucleic Acids Research. 48, 18, p. 10125-10141

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Scopus citations: 29

RNA G-Quadruplex Structures Mediate Gene Regulation in Bacteria

Shao, X., Zhang, W., Umar, M. I., Wong, H. Y., Seng, Z., Xie, Y., Zhang, Y., & 3 othersYang, L., Kwok, C. K. & Deng, X., Jan 2020, In: mBio. 11, 1, e02926-19.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Scopus citations: 51

RNA G-quadruplex structures exist and function in vivo in plants

Yang, X., Cheema, J., Zhang, Y., Deng, H., Duncan, S., Umar, M. I., Zhao, J., & 4 othersLiu, Q., Cao, X., Kwok, C. K. & Ding, Y., 2020, In: Genome Biology. 21, 226.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Scopus citations: 74

G-Quadruplex-Based Fluorescent Turn-On Ligands and Aptamers: From Development to Applications

Umar, M. I., Ji, D., Chan, C. & Kwok, C. K., Jul 2019, In: Molecules. 24, 13, 2416.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Scopus citations: 66

Spectroscopic analysis reveals the effect of a single nucleotide bulge on G-quadruplex structures

Chan, C., Umar, M. I. & Kwok, C. K., 4 Mar 2019, In: Chemical Communications. 55, 18, p. 2616-2619

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Scopus citations: 19

Structural analysis reveals the formation and role of RNA G-quadruplex structures in human mature microRNAs

Chan, K. L., Peng, B., Umar, M. I., Chan, C., Sahakyan, A. B., Le, M. T. N. & Kwok, C. K., 4 Oct 2018, In: Chemical communications (Cambridge, England). 54, 77, p. 10878-10881

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Scopus citations: 37