Personal profile
Author IDs
ORCID iD: 0000-0003-2458-5149
Biography
I’m a fourth-year Ph.D. student at the Department of Computer Science, City University of Hong Kong, advised by Prof. Ka-Chun Wong. Before that, I received my bachelor’s degree from Wuhan University (major in MIS and minor in CS). Now, I am a joint visiting student with Prof. Manolis Kellis and Prof. Marinka Zitnik at MIT and Harvard. My research interests include AIDD (AI for drug design), Bioinformatics, and BioNLP. I am also a big fan of Real Madrid ⚽️.
I am looking for the postdoctoral and faculty postions starting from 2024 Fall. Please do not hesitate to contact me ([email protected]; [email protected]) if you are interested in my research.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations from the last five years
Research output
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DDintensity: Addressing imbalanced drug-drug interaction risk levels using pre-trained deep learning model embeddings
Xie, W., Chen, X., Huang, L., Zheng, Z., Wang, Y., Zhang, R., Zhang, X., Liu, Z., Peng, C., Gullerova, M. & Wong, K.-C., Oct 2025, In: Artificial Intelligence in Medicine. 168, 103202.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
3 Link opens in a new tab Citations (Scopus) -
scPER2P: Parameter-Efficient Single-Cell LLM for Translated Proteome Profiles
Wang, Y., Chen, X., Zheng, Z., Xie, W., Wang, F., Huang, L. & Wong, K. C., 2025, Neural Information Processing: 31st International Conference, ICONIP 2024, Auckland, New Zealand, December 2–6, 2024, Proceedings, Part V. Mahmud, M., Doborjeh, M., Wong, K., Leung, A. C. S., Doborjeh, Z. & Tanveer, M. (eds.). Singapore: Springer , p. 1-15 (Lecture Notes in Computer Science; vol. 15290).Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review
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Unveiling Multi-Scale Architectural Features in Single-Cell Hi-C Data Using scCAFE
Wang, F., Lin, J., Alinejad-Rokny, H., Ma, W., Meng, L., Huang, L., Yu, J., Chen, N., Wang, Y., Yao, Z., Xie, W., Wong, K.-C. & Li, X., 20 Jun 2025, In: Advanced Science. 12, 23, 15 p., 2416432.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)9 Downloads (CityUHK Scholars) -
A dual diffusion model enables 3D molecule generation and lead optimization based on target pockets
Huang, L., Xu, T., Yu, Y., Zhao, P., Chen, X., Han, J., Xie, Z., Li, H., Zhong, W., Wong, K.-C. & Zhang, H., 2024, In: Nature Communications. 15, 2657.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile117 Link opens in a new tab Citations (Scopus)59 Downloads (CityUHK Scholars) -
A Unified Conditional Diffusion Framework for Dual Protein Targets-Based Bioactive Molecule Generation
Huang, L., Yuan, Z., Yan, H., Sheng, R., Liu, L., Wang, F., Xie, W., Chen, N., Huang, F., Huang, S., Wong, K.-C. & Zhang, Y., Sept 2024, In: IEEE Transactions on Artificial Intelligence. 5, 9, p. 4595-4606Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
5 Link opens in a new tab Citations (Scopus)
Prizes
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Outstanding Academic Performance Award for Research Degree Students (non-local UGC-funded students)
HUANG, L. (Recipient), 16 Aug 2022
Prize: RGC 64B - Prizes and awards
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Thesis
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Multi-Modality Machine Learning Approaches for High Throughput Drug Development
HUANG, L. (Author), WONG, K. C. (Supervisor), 23 Aug 2024Student thesis: Doctoral Thesis