Dr. CHAN Kui Ming (陳居明)

Research Output

  1. 2020
  2. Accepted/In press/Filed

    MCM3相關乳腺癌生物標誌物試劑盒, 診斷系統及其相關應用

    CHAN, K. M., ZHU, L. & ZHU, X., 7 Sep 2020, (Accepted/In press/Filed) Priority No. 202010927463.8

    Research output: Patents, Agreements and Assignments (RGC: 51, 52, 53)51_Patents granted (CityU only, data source from KTO)

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  3. Published

    CRISPR-assisted detection of RNA–protein interactions in living cells

    Yi, W., Li, J., Zhu, X., Wang, X., Fan, L., Sun, W., Liao, L. & 8 others, Zhang, J., Li, X., Ye, J., Chen, F., Taipale, J., Chan, K. M., Zhang, L. & Yan, J., Jul 2020, In : Nature Methods. 17, 7, p. 685–688 4 p.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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  4. Published

    Cancer-associated histone mutation H2BG53D disrupts DNA-histone octamer interaction and promotes oncogenic phenotypes

    Wan, Y. C. E., Leung, T. C. S., Ding, D., Sun, X., Liu, J., Zhu, L., Kang, T. Z. E. & 13 others, Yang, D., Zhang, Y., Zhang, J., Qian, C., Huen, M. S. Y., Li, Q., Chow, M. Z. Y., Zheng, Z., Han, J., Goel, A., Wang, X., Ishibashi, T. & Chan, K. M., 2020, In : Signal Transduction and Targeted Therapy. 5, 27.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 1
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  5. Published
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  6. 2019
  7. Published

    TSPYL2 Regulates the Expression of EZH2 Target Genes in Neurons

    Liu, H., Peng, L., So, J., Tsang, K. H., Chong, C. H., Mak, P. H. S., Chan, K. M. & 1 others, Chan, S. Y., Apr 2019, In : Molecular Neurobiology. 56, 4, p. 2640-2652

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 4
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  8. 2018
  9. Published

    Rtt105 functions as a chaperone for replication protein A to preserve genome stability

    Li, S., Xu, Z., Xu, J., Zuo, L., Yu, C., Zheng, P., Gan, H. & 16 others, Wang, X., Li, L., Sharma, S., Chabes, A., Li, D., Wang, S., Zheng, S., Li, J., Chen, X., Sun, Y., Xu, D., Han, J., Chan, K., Qi, Z., Feng, J. & Li, Q., 3 Sep 2018, In : EMBO Journal. 37, 17, e99154.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 3
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  10. Published

    RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair

    An, L., Dong, C., Li, J., Chen, J., Yuan, J., Huang, J., Chan, K. M. & 2 others, Yu, C. & Huen, M. S. Y., 28 Aug 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 35, p. E8286-E8295

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 10
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  11. Published

    Histone H3 Mutations in Cancer

    Wan, Y. C. E., Liu, J. & Chan, K. M., Aug 2018, In : Current Pharmacology Reports. 4, 4, p. 292-300

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 8
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  12. Published

    Mechanism of cancer: Oncohistones in action

    Qiu, L., Hu, X., Jing, Q., Zeng, X., Chan, K. & Han, J., 20 May 2018, In : Journal of Genetics and Genomics. 45, 5, p. 227-236

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 3
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  13. 2016
  14. Published

    The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

    Stunnenberg, H. G., The International Human Epigenome Consortium, 228 authors, including, T. I. H. E. C. 2. A. I., Abrignani, S., Chan, K. M. & Hirst, M., 17 Nov 2016, In : Cell. 167, 5, p. 1145-1149

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)Comment/debate

    Scopus citations: 125
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  15. Published

    Replication Independent Chromatin Function of MCM3

    CHAN, K. M., 25 Jul 2016.

    Research output: Conference Papers (RGC: 31A, 31B, 32, 33)31A_Invited conference paper (refereed items)Invited

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  16. 2015
  17. Published

    Epigenetics in Gene regulation and human diseases

    CHAN, K. M., 16 Dec 2015.

    Research output: Conference Papers (RGC: 31A, 31B, 32, 33)31A_Invited conference paper (refereed items)Invitedpeer-review

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  18. 2013
  19. A lesson learned from the H3.3K27M mutation found in pediatric glioma A new approach to the study of the function of histone modifications in vivo?

    Chan, K. M., Han, J., Fang, D., Gan, H. & Zhang, Z., 15 Aug 2013, In : Cell Cycle. 12, 16, p. 2546-2552

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 31
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  20. The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

    Chan, K., Fang, D., Gan, H., Hashizume, R., Yu, C., Schroeder, M., Gupta, N. & 5 others, Mueller, S., David James, C., Jenkins, R., Sarkaria, J. & Zhang, Z., 1 May 2013, In : Genes and Development. 27, 9, p. 985-990

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 334
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  21. 2012
  22. When MT1-MMP meets ADAMs

    Wong, H. L. X., Cao, R., Jin, G., Chan, K. M., Cao, Y. & Zhou, Z., 1 Aug 2012, In : Cell Cycle. 11, 15, p. 2793-2798

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)62_Review of books or of software (or similar publications/items)

    Scopus citations: 10
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  23. MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis

    Chan, K. M., Wong, H. L. X., Jin, G., Liu, B., Cao, R., Cao, Y., Lehti, K. & 2 others, Tryggvason, K. & Zhou, Z., 12 Jun 2012, In : Developmental Cell. 22, 6, p. 1176-1190

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 44
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  24. Leucine-rich repeat and WD repeat-containing protein 1 is recruited to pericentric heterochromatin by trimethylated lysine 9 of histone H3 and maintains heterochromatin silencing

    Chan, K. M. & Zhang, Z., 27 Apr 2012, In : Journal of Biological Chemistry. 287, 18, p. 15024-15033

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 23
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  25. 2011
  26. Diverse factors are involved in maintaining X chromosome inactivation

    Chan, K. M., Zhang, H., Malureanu, L., Van Deursen, J. & Zhang, Z., 4 Oct 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 40, p. 16699-16704

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 29
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  27. MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell development

    Jin, G., Zhang, F., Chan, K. M., Xavier Wong, H. L., Liu, B., Cheah, K. S. E., Liu, X. & 3 others, Mauch, C., Liu, D. & Zhou, Z., 1 Jun 2011, In : EMBO Journal. 30, 11, p. 2281-2293

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 29
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  28. 2010
  29. FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase - FGFR4 complex

    Sugiyama, N., Varjosalo, M., Meller, P., Lohi, J., Chan, K. M., Zhou, Z., Alitalo, K. & 3 others, Taipale, J., Keski-Oja, J. & Lehti, K., 7 Sep 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 36, p. 15786-15791

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

    Scopus citations: 36
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