Prof. YUAN Hsiang-Yu Sean (阮相宇)

PhD (Duke University)

Visiting address
Phone: +852 34426660

Author IDs

Willing to take PhD students: yes
Willing to talk to media: yes


Dr Yuan received his Bachelor of Science degree in Electrical Engineering from National Central University in Taiwan in 1999. He received his Master of Science in Biomedical Engineering from National Taiwan University in 2001 working on Artificial Intelligence with a focus on Medical Natural Language Processing. He received his second Master degree in Microbiology (Immunology Division) from National Taiwan University under the guidance with Prof. Yuan-Tsong Chen at Academia Sinica. His thesis work focused on the Pharmacogenetic study of Warfarin responsiveness. In 2007, Dr Yuan pursue his PhD degree in Computational Biology & Bioinformatics in the Lab of Katia Koelle at Duke University focusing on mathematical modelling of influenza antigenic drift. After the completion of the graduate school in 2013, Dr Yuan moved to London to study the impact of herd immunity on influenza outbreak with Prof. Steven Riley at Imperial College London. Dr Yuan joined CityU as an Assistant Professor in January 2018.

Research Interests/Areas

  1. Risk assessment of current COVID-19 by modelling the impacts of border controls, vaccination and other public health measures.
  2. Forecasting of Dengue disease transmission and mathematical modelling of Mosquito lifecycle.
  3. Use mathematical modelling and evolutionary analysis to study the interplay between virus evolution and host immunity dynamics in the population, including how binding avidity adaptation limits disease transmission and diversity. 
  4. Translation of medical discoveries into policies in Epidemiology and public health. For example, to evaluate and predict vaccination outcomes in a population considering vaccine waning.