Mr. YAO Houzong (姚后宗)

Research Output

  1. 2023
  2. Published

    An ultrasound-activatable platinum prodrug for sono-sensitized chemotherapy

    Liu, G., Zhang, Y., Yao, H., Deng, Z., Chen, S., Wang, Y., Peng, W., & 7 othersSun, G., Tse, M., Chen, X., Yue, J., Peng, Y., Wang, L. & Zhu, G., 23 Jun 2023, In: Science Advances. 9, 25, eadg5964.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 10
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  3. Published

    Synthesis, Characterization, and Cytotoxicity of a Reactive Platinum(IV) Monotrifluoromethyl Complex

    Liu, Y., Yao, H., Tse, M., Chen, S., Yiu, S. & Zhu, G., 13 Jan 2023, In: European Journal of Inorganic Chemistry. 26, 3, e202200438.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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  4. Published

    Platinum anticancer drugs: Targeting and delivery

    Deng, Z., Yao, H., Wang, Z. & Zhu, G., 2023, Comprehensive Inorganic Chemistry III. Reedijk, J., Poeppelmeier, K. R., Pecoraro, V. L. & Guo, Z. (eds.). Elsevier, Vol. 2. p. 808-846 2.25

    Research output: Chapters, Conference Papers, Creative and Literary Works (RGC: 12, 32, 41, 45)12_Chapter in an edited book (Author)peer-review

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  5. 2022
  6. Published

    Blood Components as Carriers for Small-Molecule Platinum Anticancer Drugs

    Yao, H. & Zhu, G., 5 Dec 2022, In: ChemMedChem. 17, 23, e202200482.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 1
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  7. Published

    Enhancing Circulation and Tumor Accumulation of Carboplatin via an Erythrocyte-Anchored Prodrug Strategy

    Yao, H., Wang, Z., Wang, N., Deng, Z., Liu, G., Zhou, J., Chen, S., & 2 othersShi, J. & Zhu, G., 20 Jun 2022, In: Angewandte Chemie - International Edition. 61, 25, e202203838.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 17
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  8. Published

    A platinum-based fluorescent "turn on" sensor to decipher the reduction of platinum(iv) prodrugs

    Yao, H. & Zhu, G., 14 Apr 2022, In: Dalton Transactions. 51, 14, p. 5394-5398

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 6
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  9. Published

    The influence of different carbonate ligands on the hydrolytic stability and reduction of platinum(IV) prodrugs

    Chen, S., Ng, K., Zhou, Q., Yao, H., Deng, Z., Tse, M. & Zhu, G., 21 Jan 2022, In: Dalton Transactions. 51, 3, 885–897.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 4
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  10. 2021
  11. Published

    Optimization of axial ligands to promote the photoactivation of BODIPY-conjugated platinum(IV) anticancer prodrugs

    Yao, H., Gunawan, Y. F., Liu, G., Tse, M. & Zhu, G., 21 Oct 2021, In: Dalton Transactions. 50, 39, p. 13737-13747

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 12
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  12. Published

    An intramolecular photoswitch can significantly promote photoactivation of Pt(iv) prodrugs

    Deng, Z., Li, C., Chen, S., Zhou, Q., Xu, Z., Wang, Z., Yao, H., & 2 othersHirao, H. & Zhu, G., 21 May 2021, In: Chemical Science. 12, 19, p. 6536-6542 7 p.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 29
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  13. 2020
  14. Published

    BODI-Pt, a Green-Light-Activatable and Carboplatin-Based Platinum(IV) Anticancer Prodrug with Enhanced Activation and Cytotoxicity

    Yao, H., Chen, S., Deng, Z., Tse, M., Matsuda, Y. & Zhu, G., 17 Aug 2020, In: Inorganic Chemistry. 59, 16, p. 11823-11833

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 38
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  15. Published

    Stability, Reduction, and Cytotoxicity of Platinum(IV) Anticancer Prodrugs Bearing Carbamate Axial Ligands: Comparison with Their Carboxylate Analogues

    Chen, S., Yao, H., Zhou, Q., Tse, M., Gunawan, Y. F. & Zhu, G., 17 Aug 2020, In: Inorganic Chemistry. 59, 16, p. 11676–11687

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 26
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  16. 2019
  17. Published

    Synthesis and Cytotoxic Study of a Platinum(IV) Anticancer Prodrug with Selectivity toward Luteinizing Hormone-Releasing Hormone (LHRH) Receptor-Positive Cancer Cells

    Yao, H., Xu, Z., Li, C., Tse, M., Tong, Z. & Zhu, G., 19 Aug 2019, In: Inorganic Chemistry. 58, 16, p. 11076−11084

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 18
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  18. 2017
  19. A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer

    Li, F., Lu, J., Liu, J., Liang, C., Wang, M., Wang, L., Li, D., & 19 othersYao, H., Zhang, Q., Wen, J., Zhang, Z., Li, J., Lv, Q., He, X., Guo, B., Guan, D., Yu, Y., Dang, L., Wu, X., Li, Y., Chen, G., Jiang, F., Sun, S., Zhang, B., Lu, A. & Zhang, G., 9 Nov 2017, In: Nature Communications. 8, 1390, p. 1-14 1390.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 194
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  20. Chemical Modifications of Nucleic Acid Aptamers for Therapeutic Purposes

    Ni, S., Yao, H., Wang, L., Lu, J., Jiang, F., Lu, A. & Zhang, G., Aug 2017, In: International Journal of Molecular Sciences. 18, 8, p. 1-21 1683.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 214
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  21. 2016
  22. Antischistosomal activity of N,N’-arylurea analogs against Schistosoma japonicum

    Yao, H., Liu, F., Chen, J., Li, Y., Cui, J. & Qiao, C., 1 Mar 2016, In: Bioorganic & Medicinal Chemistry Letters. 26, 5, p. 1386-1390 5 p.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 21
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  23. Methods to Design and Synthesize Antibody-Drug Conjugates (ADCs)

    Yao, H., Jiang, F., Lu, A. & Zhang, G., Feb 2016, In: International Journal of Molecular Sciences. 17, 2, 194.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 54
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  24. Prodrug Strategies for Paclitaxel

    Meng, Z., Lv, Q., Lu, J., Yao, H., Lv, X., Jiang, F., Lu, A., & 1 othersZhang, G., 2016, In: International Journal of Molecular Sciences. 17, 5, 796.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 70
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  25. 2015
  26. Design, synthesis and biological evaluation of praziquantel and endoperoxide conjugates as antischistosomal agents

    Yang, J., Boissier, J., Chen, J., Yao, H., Yang, S., Rognon, A. & Qiao, C., Apr 2015, In: Future Medicinal Chemistry. 7, 6, p. 713-725 13 p.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 13
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  27. 2014
  28. 一种氟代丁酸腺苷衍生物的合成

    姚后宗, 尹伟 , 陈晶磊 & 乔春华, 25 Jun 2014, In: Chinese Journal of Organic Chemistry. 34, 6, p. 1222-1226 5 p.

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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