Personal profile
Author IDs
ORCID iD: 0000-0001-7680-5110
Scopus Author ID: 56031027100
Google Scholar Profile: GHfNCxUAAAAJ
Impact
Biography
BVSc, PhD, Dip. ACVP (Anatomic), MRCVS
HK specialist in Veterinary Anatomic Pathology
Prof. Fabian Lean is an Assistant Professor of Veterinary Virology at City University of Hong Kong and a board-certified veterinary anatomic pathologist. He received his veterinary and postgraduate training at the University of Queensland, the University of Melbourne, the Australian Centre for Disease Preparedness (ACDP–CSIRO), and the Royal Veterinary College (UK). He is a registered member of the Royal College of Veterinary Surgeons (UK).
He has authored and co-authored over 50 scientific articles in international peer-reviewed journals and serves as an Academic Editor for Transboundary and Emerging Diseases.
Position(s) Available
Our group is seeking a highly motivated PhD student with a strong background in one or more of the following areas: molecular biology, virology, microscopy, or bioinformatics. Candidates with a veterinary background are also welcome. The ideal applicant will be enthusiastic about interdisciplinary research, combining wet-lab virology and computational approaches to study virus-host interactions and mechanisms of disease in viral infections affecting animals, humans, or zoonosis.
Also welcome enquiries about final year BVM research project.
Research Interests/Areas
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Risk Assessment of Emerging Viruses
Mapping virus entry receptors and virus-host binding sites in mammalian and avian tissues to understand virus entry mechanism and to predict animal host susceptibility to virus infection. -
Mechanistic Studies of Viral Disease Pathogenesis
Investigating molecular pathways and immune responses driving tissue-level damage in respiratory, encephalitic, and hemorrhagic viral diseases, using spatial transcriptomics and AI to identify biomarkers linked to clinico-pathological parameters in animal models relevant to animal, human, or zoonotic disease.
Education/Academic qualification
Fellow, Anatomic Pathology Residency, The Royal Veterinary College
2022 → 2025
PhD, Pathology & Virology, Australian Centre for Disease Preparedness
2016 → 2019
BSc (Hons), Bachelor of Veterinary Science (Hons I), University of Queensland
2011 → 2015
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 14 Life Below Water -
SDG 15 Life on Land
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Collaborations from the last five years
Research output
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Differential susceptibility of SARS-CoV-2 in animals: Evidence of ACE2 host receptor distribution in companion animals, livestock and wildlife by immunohistochemical characterisation
Lean, F. Z. X., Núñez, A., Spiro, S., Priestnall, S. L., Vreman, S., Bailey, D., James, J., Wrigglesworth, E., Suarez-Bonnet, A., Conceicao, C., Thakur, N., Byrne, A. M. P., Ackroyd, S., Delahay, R. J., van der Poel, W. H. M., Brown, I. H., Fooks, A. R. & Brookes, S. M., Jul 2022, In: Transboundary and Emerging Diseases. 69, 4, p. 2275-2286 12 p.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile42 Link opens in a new tab Citations (Scopus)1 Downloads (CityUHK Scholars) -
Comparative evaluation of disease dynamics in wild boar and domestic pigs experimentally inoculated intranasally with the European highly virulent African swine fever virus genotype II strain "Armenia 2007"
Sánchez-Cordón, P. J., Lean, F. Z. X., Batten, C., Steinbach, F., Neimanis, A., Le Potier, M.-F., Wikström-Lassa, E., Wynne, F., Strong, R., McCleary, S., Crooke, H., Gavier-Widén, D. (Co-last Author) & Núñez, A. (Co-last Author), 2024, In: Veterinary Research. 55, 16 p., 89.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile7 Link opens in a new tab Citations (Scopus) -
Encephalitis and Death in Wild Mammals at a Rehabilitation Center after Infection with Highly Pathogenic Avian Influenza A(H5N8) Virus, United Kingdom
Floyd, T., Banyard, A. C., Lean, F. Z. X., Byrne, A. M. P., Fullick, E., Whittard, E., Mollett, B. C., Bexton, S., Swinson, V., Macrelli, M., Lewis, N. S., Reid, S. M., Núñez, A., Duff, J. P., Hansen, R. & Brown, I. H., Nov 2021, In: Emerging Infectious Diseases. 27, 11, p. 2856-2863 8 p.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile74 Link opens in a new tab Citations (Scopus)2 Downloads (CityUHK Scholars) -
Detection of Usutu virus infection in wild birds in the United Kingdom, 2020
Folly, A. J., Lawson, B., Lean, F. Z., McCracken, F., Spiro, S., John, S. K., Heaver, J. P., Seilern-Moy, K., Masters, N., Hernández-Triana, L. M., Phipps, L. P., Nuñez, A., Fooks, A. R., Cunningham, A. A., Johnson, N. & McElhinney, L. M., 15 Oct 2020, In: Eurosurveillance. 25, 41, 2001732.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open AccessFile53 Link opens in a new tab Citations (Scopus)1 Downloads (CityUHK Scholars) -
Highly pathogenic avian influenza virus H5N1 infection in skua and gulls in the United Kingdom, 2022
Lean, F. Z. X., Falchieri, M., Furman, N., Tyler, G., Robinson, C., Holmes, P., Reid, S. M., Banyard, A. C., Brown, I. H., Man, C. & Núñez, A., May 2024, In: Veterinary Pathology. 61, 3, p. 421-431 11 p.Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Open Access20 Link opens in a new tab Citations (Scopus)
Projects
- 1 Active
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REG-Small Scale: Early Zoonotic Threat Assessment Through Evaluating Animal Susceptibility to Influenza and Coronaviruses
LEAN, F. (Principal Investigator / Project Coordinator) & VIDANA, B. (Co-Investigator)
1/05/26 → …
Project: Research