Prof. KWOK Chun Kit (郭駿傑)

Research Output

  1. 2024
  2. Accepted/In press/Filed

    ​Stem-loop Structured Library for G4-SELEX-Seq: Design, Methods, and Applications

    KWOK, C. K. & JI, D., 12 Jun 2024, (Accepted/In press/Filed) Priority No. 63/659,318

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  3. Accepted/In press/Filed

    ​An L-aptamer-ASO conjugate can specifically recognize a particular RNA G-quadruplex region and modulate gene activity

    KWOK, C. K. & ZHAO, H., 20 May 2024, (Accepted/In press/Filed) Priority No. 63/649,850

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  4. Published

    一種dU5`銜接子及其應用和構建的cDNA文庫

    KWOK, C. K., YEUNG, P. Y. & ZHAO, J., 12 Apr 2024, Patent No. ZL202110037475.8, Priority No. 202110037475.8

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  5. Accepted/In press/Filed

    Aptamer-Peptide Conjugates

    KWOK, C. K. & ZHANG, K., 1 Mar 2024, (Accepted/In press/Filed) Priority No. 18/593,510

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  6. Published

    Rational Design of L-RNA Aptamer-Peptide Conjugate for Efficient Cell Uptake and G-quadruplex-Mediated Gene Control

    Zhang, K., Nie, Q., Chi-Kong Lau, T. & Kit Kwok, C., 26 Feb 2024, In: Angewandte Chemie - International Edition. 63, 9, e202310798.

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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  7. Accepted/In press/Filed

    G4-Specific Peptides And Methods Of Identifying The Same

    KWOK, C. K. & MOU, X., 30 Jan 2024, (Accepted/In press/Filed) Priority No. 18/427,626

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  8. 2023
  9. Accepted/In press/Filed

    Rna G-Quadruplex Based Proteolysis-Targeting Chimeras

    KWOK, C. K. & ZHANG, K., 29 Nov 2023, (Accepted/In press/Filed) Priority No. 63/604,171

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  10. Published

    Selective targeting of parallel G-quadruplex structure using L-RNA aptamer

    Ji, D., Yuan, J., Chen, S., Tan, J. & Kwok, C. K., 27 Nov 2023, In: Nucleic acids research. 51, 21, p. 11439-11452

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 1
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  11. Published

    Modified nucleic acid aptamers: development, characterization, and biological applications

    Ji, D., Feng, H., Liew, S. W. & Kwok, C. K., Nov 2023, In: Trends in Biotechnology. 41, 11, p. 1360-1384 25 p.

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 9
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  12. Accepted/In press/Filed

    ​​Development of non-G4-containing L-RNA aptamer for RNA structure​ and the applications thereof​

    KWOK, C. K., 6 Sept 2023, (Accepted/In press/Filed) Priority No. 63/580,950

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  13. Published

    Peptides Selected by G4-mRNA Display-Seq Enable RNA G-Quadruplex Recognition and Gene Regulation

    Mou, X. & Kwok, C. K., 30 Aug 2023, In: Journal of the American Chemical Society. 145, 34, p. 18693–18697

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 4
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  14. Published

    A G-quadruplex structure in microRNA interferes with messenger RNA recognition and controls gene expression

    Lyu, K. & Kwok, C. K., 7 Jul 2023, In: Chemical Communications. 59, 53, p. 8230-8233

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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  15. Published

    Aptamers targeting SARS-COV-2: a promising tool to fight against COVID-19

    Zhang, Y., Juhas, M. & Kwok, C. K., Apr 2023, In: Trends in Biotechnology. 41, 4, p. 528-544

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 30
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  16. Published

    Tuning Material States and Functionalities of G-Quadruplex-Modulated RNA-Peptide Condensates

    Guo, W., Ji, D., Kinghorn, A. B., Chen, F., Pan, Y., Li, X., Li, Q., & 3 othersHuck, W. T. S., Kwok, C. K. & Shum, H. C., 1 Feb 2023, In: Journal of the American Chemical Society. 145, 4, p. 2375–2385

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 6
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  17. Published

    Aptamers as Functional Modules for DNA Nanostructures

    Shiu, S. C., Kinghorn, A. B., Guo, W., Slaughter, L. S., Ji, D., Mo, X., Wang, L., & 5 othersTran, N. C., Kwok, C. K., Shum, A. H. C., Tse, E. C. M. & Tanner, J. A., 2023, DNA and RNA Origami: Methods and Protocols. Valero, J. (ed.). New York, NY: Humana Press, p. 301-337 (Methods in Molecular Biology; vol. 2639).

    Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 12 - Chapter in an edited book (Author)peer-review

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  18. Published

    RNA G-quadruplex (rG4) structure detection using RTS and SHALiPE assays

    Lyu, K. & Kwok, C. K., 2023, In: Methods in Enzymology. 691, p. 63-80 18 p.

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 1
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  19. 2022
  20. Published

    An RNA G-Quadruplex Structure within the ADAR 5’UTR Interacts with DHX36 Helicase to Regulate Translation

    Lyu, K., Chen, S., Chow, E. Y., Zhao, H., Yuan, J., Cai, M., Shi, J., & 3 othersChan, T., Tan, J. & Kwok, C. K., 23 Dec 2022, In: Angewandte Chemie (International Edition). 61, 52, e202203553.

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 7
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  21. Published

    Capture-SELEX: Selection Strategy, Aptamer Identification, and Biosensing Application

    Lam, S. Y., Lau, H. L. & Kwok, C. K., Dec 2022, In: Biosensors. 12, 12, 1142.

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 12
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  22. Accepted/In press/Filed

    L-Rna Aptamers And Methods Of Identifying The Same

    KWOK, C. K. & JI, D., 4 Nov 2022, (Accepted/In press/Filed) Priority No. 18/052,811

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

    Check@CityULib
  23. Published

    Novel L-RNA Aptamer Controls APP Gene Expression in Cells by Targeting RNA G-Quadruplex Structure

    Zhao, H., Wong, H. Y., Ji, D., Lyu, K. & Kwok, C. K., 13 Jul 2022, In: ACS Applied Materials & Interfaces. 14, 27, p. 30582-30594

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 7
    Check@CityULib
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