Prof. KWOK Chun Kit (郭駿傑)

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Research Output

  1. 2025
  2. Accepted/In press/Filed

    Rapid and sensitive one-pot CRISPR/Cas12a-based detection of ​enteroaggregative Escherichia coli​​

    LIM, C. K. (Inventor), LIEW, S. W. (Inventor), KWOK, C. K. (Inventor) & LEE, P. K. H. (Inventor), 14 Feb 2025, (Accepted/In press/Filed) Priority No. 63/758,868

    Research output: Patents, Agreements and Assignments › RGC 51 - Patents (CityUHK)

    Check@CityULib
  3. Published

    RNA G-quadruplex structure-based PROTACs for targeted DHX36 protein degradation and gene activity modulation in mammalian cells

    Zhang, K. (Co-first Author), Nie, Q. (Co-first Author), Li, M. (Co-first Author), Chen, X., Zhong, L., Dai, T. & Guo, X. & 5 others, Zhao, H., Lau, T.C.-K., Wang, H., Chen, S.-B. & Kwok, C. K., 10 Feb 2025, In: Nucleic Acids Research. 53, 3, gkaf039.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Check@CityULib
  4. Published

    Pre-Defined Stem-Loop Structure Library for the Discovery of L-RNA Aptamers that Target RNA G-Quadruplexes

    Ji, D., Wang, B., Lo, K. W., Tsang, C. M. & Kwok, C. K., 27 Jan 2025, In: Angewandte Chemie International Edition. 64, 5, e202417247.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Check@CityULib
  5. 2024
  6. Published

    Selective recognition of RNA G-quadruplex in vitro and in cells by L-aptamer–D-oligonucleotide conjugate

    Zhao, H., Lau, H. L., Zhang, K. & Kwok, C. K., 11 Dec 2024, In: Nucleic acids research. 52, 22, p. 13544-13560

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 1
    Check@CityULib
  7. Published

    A selective HIV-1 RNA G-quadruplex-targeting L-aptamer–D-antisense conjugate inhibits HIV-1 minus strand transfer

    Feng, H. & Kwok, C. K., 28 Nov 2024, In: Chemical Communications. 60, 92, p. 13558-13561

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 1
    Check@CityULib
  8. Accepted/In press/Filed

    Conjugates, And Uses Thereof

    KWOK, C. K. (Inventor) & ZHANG, K. (Inventor), 28 Nov 2024, (Accepted/In press/Filed) Priority No. 18/963,702

    Research output: Patents, Agreements and Assignments › RGC 51 - Patents (CityUHK)

    Check@CityULib
  9. Accepted/In press/Filed

    共軛物及其用途

    KWOK, C. K. (Inventor) & ZHANG, K. (Inventor), 28 Nov 2024, (Accepted/In press/Filed) Priority No. 202411727263.2

    Research output: Patents, Agreements and Assignments › RGC 51 - Patents (CityUHK)

    Check@CityULib
  10. Published

    DHX36 binding induces RNA structurome remodeling and regulates RNA abundance via m6A reader YTHDF1

    Zhang, Y., Zhao, J., Chen, X., Qiao, Y., Kang, J., Guo, X. & Yang, F. & 6 others, Lyu, K., Ding, Y., Zhao, Y., Sun, H., Kwok, C. K. & Wang, H., 15 Nov 2024, In: Nature Communications. 15, 19 p., 9890.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 1
    Check@CityULib
  11. Published

    Capture of RNA G-quadruplex structures using an L-RNA aptamer

    Lam, S. Y., Umar, M. I., Zhao, H., Zhao, J. & Kwok, C. K., 1 Oct 2024, In: RSC Chemical Biology. 5, 10, p. 1045-1051

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 1
    Check@CityULib
  12. Accepted/In press/Filed

    L-RNA 適體、重組多核苷酸及其於治療阿茲海默症的用途

    KWOK, C. K. (Inventor), 5 Sept 2024, (Accepted/In press/Filed) Priority No. 202411244236.X

    Research output: Patents, Agreements and Assignments › RGC 51 - Patents (CityUHK)

    Check@CityULib
  13. Online published

    Specific Targeting and Imaging of RNA G-Quadruplex (rG4) Structure Using Non-G4-Containing l-RNA Aptamer and Fluorogenic l-Aptamer

    Lau, H. L., Zhao, H., Feng, H. & Kwok, C. K., 3 Sept 2024, (Online published) In: Small Methods. 2401097.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 1
    Check@CityULib
  14. Accepted/In press/Filed

    L-Rna Aptamers, Recombinant Polynucleotides, And Uses Thereof In Treating Alzheimer’S Disease

    KWOK, C. K. (Inventor), 5 Aug 2024, (Accepted/In press/Filed) Priority No. 18/795,168

    Research output: Patents, Agreements and Assignments › RGC 51 - Patents (CityUHK)

    Check@CityULib
  15. Published

    Hook-Like DNAzyme-Activated Autocatalytic Biosensor for the Universal Detection of Pathogenic Bacteria

    Liu, Y., Shi, Y., Wang, S., Liu, S., Shang, M., Zhao, B. & Liu, H. & 4 others, Yang, C., Wang, F., Kwok, C. K. & Wang, H., 23 Jul 2024, In: Analytical Chemistry. 96, 29, p. 11951-11958

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 4
    Check@CityULib
  16. Accepted/In press/Filed

    ​An L-aptamer-ASO conjugate can specifically recognize a particular RNA G-quadruplex region and modulate gene activity

    KWOK, C. K. (Inventor) & ZHAO, H. (Inventor), 20 May 2024, (Accepted/In press/Filed) Priority No. 63/649,850

    Research output: Patents, Agreements and Assignments › RGC 51 - Patents (CityUHK)

    Check@CityULib
  17. Published

    一種dU5`銜接子及其應用和構建的cDNA文庫

    KWOK, C. K. (Inventor), YEUNG, P. Y. (Inventor) & ZHAO, J. (Inventor), 12 Apr 2024, Patent No. ZL202110037475.8, Priority No. 202110037475.8

    Research output: Patents, Agreements and Assignments › RGC 51 - Patents (CityUHK)

    Check@CityULib
  18. Accepted/In press/Filed

    Aptamer-Peptide Conjugates

    KWOK, C. K. (Inventor) & ZHANG, K. (Inventor), 1 Mar 2024, (Accepted/In press/Filed) Priority No. 18/593,510

    Research output: Patents, Agreements and Assignments › RGC 51 - Patents (CityUHK)

    Check@CityULib
  19. Published

    Rational Design of L-RNA Aptamer-Peptide Conjugate for Efficient Cell Uptake and G-quadruplex-Mediated Gene Control

    Zhang, K., Nie, Q., Chi-Kong Lau, T. & Kit Kwok, C., 26 Feb 2024, In: Angewandte Chemie - International Edition. 63, 9, e202310798.

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 2
    Check@CityULib
  20. Accepted/In press/Filed

    G4-Specific Peptides And Methods Of Identifying The Same

    KWOK, C. K. (Inventor) & MOU, X. (Inventor), 30 Jan 2024, (Accepted/In press/Filed) Priority No. 18/427,626

    Research output: Patents, Agreements and Assignments › RGC 51 - Patents (CityUHK)

    Check@CityULib
  21. 2023
  22. Accepted/In press/Filed

    Rna G-Quadruplex Based Proteolysis-Targeting Chimeras

    KWOK, C. K. (Inventor) & ZHANG, K. (Inventor), 29 Nov 2023, (Accepted/In press/Filed) Priority No. 63/604,171

    Research output: Patents, Agreements and Assignments › RGC 51 - Patents (CityUHK)

    Check@CityULib
  23. Published

    Selective targeting of parallel G-quadruplex structure using L-RNA aptamer

    Ji, D., Yuan, J.-H., Chen, S.-B., Tan, J.-H. & Kwok, C. K., 27 Nov 2023, In: Nucleic acids research. 51, 21, p. 11439-11452

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 13
    Check@CityULib
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