Prof. KWOK Chun Kit (郭駿傑)

Research Output

  1. 2024
  2. Accepted/In press/Filed

    ​An L-aptamer-ASO conjugate can specifically recognize a particular RNA G-quadruplex region and modulate gene activity

    KWOK, C. K. & ZHAO, H., 20 May 2024, (Accepted/In press/Filed) Priority No. 63/649,850

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  3. Published

    一種dU5`銜接子及其應用和構建的cDNA文庫

    KWOK, C. K., YEUNG, P. Y. & ZHAO, J., 12 Apr 2024, Patent No. ZL202110037475.8, Priority No. 202110037475.8

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  4. Accepted/In press/Filed

    Aptamer-Peptide Conjugates

    KWOK, C. K. & ZHANG, K., 1 Mar 2024, (Accepted/In press/Filed) Priority No. 18/593,510

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  5. Accepted/In press/Filed

    G4-Specific Peptides And Methods Of Identifying The Same

    KWOK, C. K. & MOU, X., 30 Jan 2024, (Accepted/In press/Filed) Priority No. 18/427,626

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  6. 2023
  7. Accepted/In press/Filed

    Rna G-Quadruplex Based Proteolysis-Targeting Chimeras

    KWOK, C. K. & ZHANG, K., 29 Nov 2023, (Accepted/In press/Filed) Priority No. 63/604,171

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  8. Published

    Selective targeting of parallel G-quadruplex structure using L-RNA aptamer

    Ji, D., Yuan, J., Chen, S., Tan, J. & Kwok, C. K., 27 Nov 2023, In: Nucleic acids research. 51, 21, p. 11439-11452

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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  9. Published

    Modified nucleic acid aptamers: development, characterization, and biological applications

    Ji, D., Feng, H., Liew, S. W. & Kwok, C. K., Nov 2023, In: Trends in Biotechnology. 41, 11, p. 1360-1384 25 p.

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 9
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  10. Accepted/In press/Filed

    ​​Development of non-G4-containing L-RNA aptamer for RNA structure​ and the applications thereof​

    KWOK, C. K., 6 Sept 2023, (Accepted/In press/Filed) Priority No. 63/580,950

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  11. Published

    Peptides Selected by G4-mRNA Display-Seq Enable RNA G-Quadruplex Recognition and Gene Regulation

    Mou, X. & Kwok, C. K., 30 Aug 2023, In: Journal of the American Chemical Society. 145, 34, p. 18693–18697

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 4
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  12. Published

    A G-quadruplex structure in microRNA interferes with messenger RNA recognition and controls gene expression

    Lyu, K. & Kwok, C. K., 7 Jul 2023, In: Chemical Communications. 59, 53, p. 8230-8233

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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  13. Published

    Aptamers targeting SARS-COV-2: a promising tool to fight against COVID-19

    Zhang, Y., Juhas, M. & Kwok, C. K., Apr 2023, In: Trends in Biotechnology. 41, 4, p. 528-544

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 28
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  14. Published

    Tuning Material States and Functionalities of G-Quadruplex-Modulated RNA-Peptide Condensates

    Guo, W., Ji, D., Kinghorn, A. B., Chen, F., Pan, Y., Li, X., Li, Q., & 3 othersHuck, W. T. S., Kwok, C. K. & Shum, H. C., 1 Feb 2023, In: Journal of the American Chemical Society. 145, 4, p. 2375–2385

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 6
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  15. Published

    Aptamers as Functional Modules for DNA Nanostructures

    Shiu, S. C., Kinghorn, A. B., Guo, W., Slaughter, L. S., Ji, D., Mo, X., Wang, L., & 5 othersTran, N. C., Kwok, C. K., Shum, A. H. C., Tse, E. C. M. & Tanner, J. A., 2023, DNA and RNA Origami: Methods and Protocols. Valero, J. (ed.). New York, NY: Humana Press, p. 301-337 (Methods in Molecular Biology; vol. 2639).

    Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 12 - Chapter in an edited book (Author)peer-review

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  16. Published

    RNA G-quadruplex (rG4) structure detection using RTS and SHALiPE assays

    Lyu, K. & Kwok, C. K., 2023, In: Methods in Enzymology. 691, p. 63-80 18 p.

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 1
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  17. 2022
  18. Published

    An RNA G-Quadruplex Structure within the ADAR 5’UTR Interacts with DHX36 Helicase to Regulate Translation

    Lyu, K., Chen, S., Chow, E. Y., Zhao, H., Yuan, J., Cai, M., Shi, J., & 3 othersChan, T., Tan, J. & Kwok, C. K., 23 Dec 2022, In: Angewandte Chemie (International Edition). 61, 52, e202203553.

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 6
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  19. Published

    Capture-SELEX: Selection Strategy, Aptamer Identification, and Biosensing Application

    Lam, S. Y., Lau, H. L. & Kwok, C. K., Dec 2022, In: Biosensors. 12, 12, 1142.

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 11
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  20. Accepted/In press/Filed

    L-Rna Aptamers And Methods Of Identifying The Same

    KWOK, C. K. & JI, D., 4 Nov 2022, (Accepted/In press/Filed) Priority No. 18/052,811

    Research output: Patents, Agreements and AssignmentsRGC 51 - Patents (CityU)

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  21. Published

    Novel L-RNA Aptamer Controls APP Gene Expression in Cells by Targeting RNA G-Quadruplex Structure

    Zhao, H., Wong, H. Y., Ji, D., Lyu, K. & Kwok, C. K., 13 Jul 2022, In: ACS Applied Materials & Interfaces. 14, 27, p. 30582-30594

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 7
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  22. Published

    Recent advances in RNA structurome

    Xu, B., Zhu, Y., Cao, C., Chen, H., Jin, Q., Li, G., Ma, J., & 14 othersYang, S. L., Zhao, J., Zhu, J., Ding, Y., Fang, X., Jin, Y., Kwok, C. K., Ren, A., Wan, Y., Wang, Z., Xue, Y., Zhang, H., Zhang, Q. C. & Zhou, Y., Jul 2022, In: Science China Life Sciences. 65, 7, p. 1285–1324

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 20
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  23. Published

    Lockd promotes myoblast proliferation and muscle regeneration via binding with DHX36 to facilitate 5' UTR rG4 unwinding and Anp32e translation

    Chen, X., Xue, G., Zhao, J., Zhang, Y., Zhang, S., Wang, W., Li, Y., & 10 othersYuan, J., He, L., Chan, C. Y., Liu, Y., Chen, W., Zhao, Y., Hu, P., Sun, H., Kwok, C. K. & Wang, H., 7 Jun 2022, In: Cell Reports. 39, 10, 110907.

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Scopus citations: 6
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