Department of Biomedical Sciences

Projects

Projects per year 2005 2016 2018 2019 2021 2024 2026

• 11 Not started
• 151 Active
• 302 Finished

Projects per year

Search results

• Finished

  DON_RMG: Antiviral and Antitumor - RMGS

  HE, M. (Principal Investigator / Project Coordinator)

  1/07/23 → 5/03/24

  Project: Research

  • Antivirus Agent 100%
  • Diseases 100%
  • Malignant Neoplasm 66%
  • Heat Shock Protein 66%
  • Virus Infection 66%

• DON: Antiviral and Antitumor

  HE, M. (Principal Investigator / Project Coordinator)

  1/07/23 → 5/03/24

  Project: Research

• ITF: Development of a Non-viral Gene Therapy Platform for Retinal Degenerative Diseases

  XIONG, W. (Principal Investigator / Project Coordinator) & LO, P. C. (Co-Investigator)

  1/04/23 → 31/03/25

  Project: Research

• ITF: Development of Point-of-Care Testing Technology and Portable Device for Simultaneous Detection of Multiple Respiratory Tract Pathogens

  YANG, M. (Principal Investigator / Project Coordinator) & ZHAI, J. (Co-Investigator)

  1/02/23 → 31/01/25

  Project: Research

• ITF: Development of Damage-healable Structural-Color Material for Waterborne Wood Paints

  YAO, X. (Principal Investigator / Project Coordinator) & Li, M. (Co-Investigator)

  1/09/22 → 31/08/24

  Project: Research

  • Electronic Circuit 100%
  • Liquid Metal 89%
  • Ionic Liquid 59%
  • Soldering 59%
  • Conductor 59%

• ITF: Autologous-Allogeneic Human Peripheral CAK-NK Cells Construction and Combination with Immune Checkpoint Inhibitors on Treatment of Genitourinary Tumors: Key Technology Innovation, Efficacy and Mechanistic Study

  ZHANG, L. (Principal Investigator / Project Coordinator), CHO, C. S. (Co-Investigator), PENG, W. (Co-Investigator) & YUE, J. (Co-Investigator)

  1/08/22 → 31/01/25

  Project: Research

  • Endosome 100%
  • Flavivirus 65%
  • PD-L1 52%
  • Autophagy 52%
  • Tretinoin 52%

• ITF: Development and Pre-clinical Study of Externally Activated Nanomedicine for Anti-Cancer Therapy 

  YANG, M. (Principal Investigator / Project Coordinator), CHAN, W. Y. K. (Co-Investigator), LIN, D. (Co-Investigator), ZHAI, J. (Co-Investigator) & ZHAO, W. (Co-Investigator)

  1/03/22 → 28/02/25

  Project: Research

  • Vascularity 100%
  • Radioactive Tracer 100%
  • Drug Screening 100%
  • Metastatic Carcinoma 100%
  • Magnetic Nanoparticle 100%

• GRF: Overcoming the Intratumor Heterogeneity By Multi-Scale Spatial Characterizations of Tumor Microenvironment for Integrative Colorectal Cancer Classification

  WANG, X. (Principal Investigator / Project Coordinator)

  1/01/22 → 1/01/22

  Project: Research

  • MicroRNA 100%
  • Xenograft 83%
  • Cancer Classification 83%
  • Squamous Cell 83%
  • Cell Line 83%

• GRF: Evolution of Virulence Plasmids and Their Role in Clinical Adaptation and Virulence Expression of ST11 Carbapenem-Resistant Klebsiella Pneumoniae

  CHEN, S. (Principal Investigator / Project Coordinator) & DENG, X. (Co-Investigator)

  1/01/22 → 1/03/23

  Project: Research

  • Klebsiella pneumoniae 100%
  • Virulence Plasmid 46%
  • Plasmid 37%
  • Antimicrobial Resistance 23%
  • Infectious Agent 22%

• ITF: Development of a Novel Therapeutic to Promote Anticancer Immunity by Manipulating Endosomal Trafficking of PD-L1

  ZHANG, L. (Principal Investigator / Project Coordinator), CHO, W. (Co-Investigator), Wang, P. (Co-Investigator) & ZHU, K. (Co-Investigator)

  1/01/22 → 31/12/24

  Project: Research

  • Endosome 100%
  • CapZ 68%
  • Flavivirus 43%
  • Centrosome 34%
  • Lipid Droplet 34%

• HMRF: Comparing Dengue Mosquito Predictivity of Gravitrap to Ovitrap Surveillance Systems Using Weather Data in Hong Kong

  YUAN, H.-Y. S. (Principal Investigator / Project Coordinator)

  1/11/21 → 18/10/24

  Project: Research

• DON_RMG: Generation of Induced-pluripotent Stem Cells (iPSCs) of Small Animals for Veterinary Regenerative Medicine - RMGS

  GO, Y. Y. (Principal Investigator / Project Coordinator) & BAN, K. (Co-Investigator)

  1/08/21 → 27/02/23

  Project: Research

• AoE(UGC)-ExtU-Lead: Centre for Medical Engineering of Molecular and Biological Probes

  Wong, N. (Main Project Coordinator [External]) & WANG, X. (Principal Investigator / Project Coordinator)

  1/06/21 → 31/10/21

  Project: Research

  • MicroRNA 100%
  • Ferroptosis 32%
  • Macrophage 32%
  • Tamsulosin 32%
  • Aptamer 32%

• SZOth-SRI: 剧毒卡尔藻释放的化感物质及其对东海原甲藻的抑制机理研究

  WANG, R. (Principal Investigator / Project Coordinator)

  1/04/21 → 31/03/24

  Project: Research

• ASDC_Sub: Characterization of Key regulators of Pseudomonas Aeruginosa Virulence

  DENG, X. (Principal Investigator / Project Coordinator)

  28/02/21 → 15/04/24

  Project: Research

  • Transcription Factors 100%
  • Pseudomonas aeruginosa 100%
  • Regulatory Network 50%
  • Type III Secretion System 16%
  • Type VI Secretion System 16%

• ASDC_Sub: Neural Cell Networking Mediated by Circadian Clocks to Enhance Brain Repair Systems

  KIM, J. Y. (Principal Investigator / Project Coordinator)

  28/02/21 → 15/04/24

  Project: Research

  • Circadian Rhythm 100%
  • Hypertonic Solution 50%
  • Catenin 50%
  • Nervous System Development 50%
  • Transcription Factors 50%

• ASDC_Sub: Development of Coordination-driven Supramolecular Nanoplatforms for Theranostic Applications

  LO, P. C. (Principal Investigator / Project Coordinator)

  28/02/21 → 15/04/24

  Project: Research

  • Tumor 100%
  • Hydrogen Peroxide 100%
  • Nanosystems 100%
  • Nanoparticle 100%
  • Glutathione 33%

• CRF: A Universal Solid/liquid-Based Framework for Efficient Water Energy Harvesting

  WANG, Z. (Principal Investigator / Project Coordinator), Qian, T. (Co-Principal Investigator), WANG, L. (Co-Principal Investigator), XU, L. (Co-Principal Investigator), YANG, Z. (Co-Principal Investigator), YAO, X. (Co-Principal Investigator) & Yao, S. (Co-Principal Investigator)

  1/02/21 → 2/02/23

  Project: Research

  • Surface (Surface Science) 100%
  • Power Generation 25%
  • Energy Harvesting 25%
  • Elastic Energy 20%
  • Surface Design 19%

• ITF: Biosensors for the Rapid Identification of Clinically Important Microorganisms

  LAM, Y. W. (Principal Investigator / Project Coordinator), LAM, H. W. M. (Co-Investigator) & LAU, C. K. T. (Co-Investigator)

  1/02/21 → 18/09/22

  Project: Research

• ASDC_Sub: Delivery of sRNA to Target Drug Resistant Bacteria

  LAU, C. K. T. (Principal Investigator / Project Coordinator)

  1/02/21 → 15/04/24

  Project: Research

  • Antibiotics 100%
  • Nanodiamond 100%
  • Urinary Tract Infection 100%
  • Recurrent Disease 100%
  • Intracellular Bacterium 100%

• ASDC_Sub: Screen for Molecular Targets in the Senescence Response of Tumor Cells to Chemotherapy

  ZHANG, L. (Principal Investigator / Project Coordinator)

  1/02/21 → 15/04/24

  Project: Research

  • Proteomics 100%
  • Wnt Signaling Pathway 86%
  • Hypertonic Solution 80%
  • Proteome 80%
  • Tumor Necrosis Factor 80%

• ASDC_Sub: Exploring the Molecular Mechanisms of HERV-H in Mediating Chromatin High-order Structure in Human Embryonic Stem Cells

  YAN, J. (Principal Investigator / Project Coordinator)

  1/02/21 → 15/04/24

  Project: Research

• ASDC_Sub: TLR Agonists as Plasmacytoid Dendritic Cell-based Cancer Immunotherapy

  CHOW, K. T. (Principal Investigator / Project Coordinator)

  1/02/21 → 15/04/24

  Project: Research

  • Malignant Neoplasm 100%
  • Nitric Oxide 100%
  • Photosensitizer 100%
  • Photodynamic Therapy 100%
  • Recurrent Disease 100%

• ASDC_Sub: Developing Gene Editing Therapy for Inherited Retinal Diseases

  XIONG, W. (Principal Investigator / Project Coordinator)

  1/02/21 → 26/02/25

  Project: Research

• ASDC_Sub: Intergrative Analysis of Multi-omics and Histopathology Images to Establish a Classification System for Esophageal Squamous Cell Cacinoma

  WANG, X. (Principal Investigator / Project Coordinator)

  1/02/21 → 28/04/22

  Project: Research

• ASDC_Sub: Development of 3D Organoid Models for Identifying Novel Breast Cancer Therapeutics Targeting Tumor Microenvironment and Cancer Stem Cells

  CHIN, R. Y. M. (Principal Investigator / Project Coordinator)

  1/02/21 → 15/04/24

  Project: Research

  • Protein Kinase B 100%
  • Upregulation 50%
  • Protein Tyrosine Kinase 50%
  • Protein Kinase B Inhibitor 50%
  • Breast Cancer 50%

• GRF: Mechanistic Studies of CapZβ Signaling in the Maturation of Early Endosomes

  CHAN, K. M. (Principal Investigator / Project Coordinator) & YUE, J. (Co-Investigator)

  1/01/21 → 17/12/24

  Project: Research

  • Capping Phenomenon 100%
  • Endosome 100%
  • Malignant Neoplasm 81%
  • Protein Z 75%
  • Autophagy 75%

• GRF: Inter-regional Communication Mechanisms Mediated by Circadian Clocks in Pathological Conditions of the Brain

  KIM, J. Y. (Principal Investigator / Project Coordinator)

  1/01/21 → 12/06/25

  Project: Research

  • Circadian Rhythm 100%
  • Brain Areas 31%
  • Neurodegeneration 27%
  • Mouse Brain 27%
  • Neurogenesis 27%

• GRF: Concerted Activation of Photosensitizers and Release of Anticancer Drugs Through Tetrazine-Induced Bioorthogonal Decaging Reactions

  LO, P. C. (Principal Investigator / Project Coordinator) & NG, K. P. D. (Co-Investigator)

  1/01/21 → 24/06/25

  Project: Research

  • Photosensitizer 100%
  • Tetrazine 100%
  • Neoplasm 77%
  • Anticancer Drug 66%
  • Antineoplastic Agent 66%

• GRF: Endothelial Cell Nrf2 Activation Inhibits Atherosclerosis

  HUANG, Y. (Principal Investigator / Project Coordinator)

  1/01/21 → 17/12/24

  Project: Research

  • Atherosclerosis 100%
  • Endothelial Cell 80%
  • Inflammation 77%
  • Transcription Factor Nrf2 56%
  • Vascular Disease 41%

• GRF: Developing High-strength Supramolecular Adhesives with Controlled Liquid Inclusion: from Mechanistic Study to Antibacterial Applications

  YAO, X. (Principal Investigator / Project Coordinator)

  1/01/21 → 23/12/24

  Project: Research

  • Hydrogel 100%
  • Surface (Surface Science) 89%
  • Hydrogen Bonding 63%
  • Ionic Liquid 60%
  • Biomedical Application 53%

• GRF: Health Effects of Neighborhood Walkability on Chinese Adults: Analysis of an Existing Longitudinal Cohort

  LAO, X. (Principal Investigator / Project Coordinator), Guo, C. (Co-Investigator), RUDGE, G. (Co-Investigator) & THOMAS, G. N. (Co-Investigator)

  1/01/21 → 12/06/25

  Project: Research

  • Proportional Hazards Model 100%
  • Regression Model 100%
  • Mediation Analysis 94%
  • Three-Dimension 94%
  • Generalized Linear Mixed Model 94%

• NSFC-GP-SRI: Zswim4在骨骼发育及再生中的功能和机制研究

  MAK, K. L. K. (Principal Investigator / Project Coordinator)

  1/01/21 → 31/12/24

  Project: Research

• GRF: Revealing Signaling Pathway of Novel Two-component System TsiRS in Regulating Virulence of Pseudomonas Syringae

  DENG, X. (Principal Investigator / Project Coordinator) & Ji, Q. (Co-Investigator)

  1/01/21 → 8/02/24

  Project: Research

  • Pseudomonas syringae 100%
  • Type Three Secretion System 63%
  • Transcription Factors 40%
  • Type III Secretion System 32%
  • Regulatory Network 30%

• ITF: Precision Prediction Models for COVID-19

  CHAN, K. H. K. (Principal Investigator / Project Coordinator)

  1/12/20 → 31/05/22

  Project: Research

  • Random Forest 100%
  • Biological Marker 100%
  • COVID-19 100%
  • COVID-19 Mortality 100%
  • Electronic Medical Record 50%

• HMRF: Modelling of Hong Kong COVID-19 Control Strategies Considering Different Population Immunity Scenarios

  YUAN, H.-Y. S. (Principal Investigator / Project Coordinator), PFEIFFER, D. U. (Co-Investigator), QIN, S. J. (Co-Investigator), WANG, X. (Co-Investigator) & ZHANG, Q. (Co-Investigator)

  1/11/20 → 24/04/24

  Project: Research

  • COVID-19 100%
  • Infection 45%
  • Observational Study 32%
  • Social Distancing 25%
  • Non-Pharmaceutical Intervention 24%

• ITF-ExtU-Lead: COVID-19 Detection based on Fluorescence Polarization Measurement

  YANG, M. (Principal Investigator / Project Coordinator)

  1/11/20 → 31/10/21

  Project: Research

• HMRF: Selective PPARα Activation Directly Protects Vascular Function through Inhibition of YAP/TAZ-Mediated Oxidative Stress and Inflammation

  HUANG, Y. (Principal Investigator / Project Coordinator), Luo, J.-Y. (Co-Investigator) & Tomlinson, B. (Co-Investigator)

  15/09/20 → 24/04/24

  Project: Research

  • Inflammation 100%
  • Atherosclerosis 58%
  • Atherogenesis 55%
  • Endothelial Cell 46%
  • Endothelial Dysfunction 45%

• HMRF: Development of Big Data Tools for High-Throughput Sequencing Data with Applications to Colorectal Cancer Genomes

  WONG, K. C. (Principal Investigator / Project Coordinator) & WANG, X. (Co-Investigator)

  1/09/20 → 13/11/23

  Project: Research

  • Deep Learning Method 100%
  • RNA Sequencing 63%
  • RNA Sequence 63%
  • High Throughput 61%
  • Transcriptomics 53%

• ECS: Dissect the Molecular Mechanisms of HERV-H Mediated Shaping of Chromatin 3D Structure in Human Pluripotent Stem Cells

  YAN, J. (Principal Investigator / Project Coordinator)

  1/08/20 → 25/06/24

  Project: Research

  • RNA 100%
  • Genomics 64%
  • Stem Cell 57%
  • Transcription Factors 57%
  • Non-Coding RNA 38%

• SZOth-SRI: 开发天然双苄基异喹啉生物碱—小檗胺及小檗胺脂质纳米制剂为一类新型高效抗SARS-CoV-2药物

  YUE, J. (Principal Investigator / Project Coordinator)

  22/07/20 → 29/06/23

  Project: Research

• HMRF: Development of a New Class of Targeted Therapeutics for Triple-Negative Breast Cancer Therapy

  LO, P. K. P. (Principal Investigator / Project Coordinator) & CHIN, R. Y. M. (Co-Investigator)

  1/07/20 → 24/04/24

  Project: Research

  • Nucleic Acid 100%
  • Antisense 79%
  • Biosensor 60%
  • Nanodiamond 60%
  • Antisense Oligonucleotide 55%

• TDG(CityU): Unraveling the Microbiome Profile on CityU Campus

  LAU, C. K. T. (Principal Investigator / Project Coordinator)

  1/06/20 → 30/11/21

  Project: Research

  • High Throughput 100%
  • Effective Method 100%
  • Potential Solution 100%
  • Infectious Agent 100%
  • Learning Experiences 100%

• DON_RMG: Development of an Integrated Microfluidics System for Multi-level High Content Screening of Anti-tumor Drugs - RMGS

  YANG, M. (Principal Investigator / Project Coordinator), CHIN, R. Y. M. (Co-Investigator), GUAN, X. Y. (Co-Investigator), WU, J. J. (Co-Investigator) & ZHANG, L. (Co-Investigator)

  1/06/20 → 29/06/22

  Project: Research

  • Neoplasm 100%
  • High-Content Screening 100%
  • Drug Screening 100%
  • Malignant Neoplasm 50%
  • Drug Development 50%

• ITF: Rapid Detection of SARS -CoV-2 Virus Using Isothermal Nucleic Acid Lateral Flow Assay (IsoNALFA) 

  YANG, M. (Principal Investigator / Project Coordinator)

  1/05/20 → 31/01/21

  Project: Research

• CRF: Non-canonical NAD-capped RNAs in Arabidopsis: Mechanisms of Capping and Decapping and Molecular and Physiological Functions

  Xia, Y. (Main Project Coordinator [External]) & HUANG, L. (Principal Investigator / Project Coordinator)

  1/04/20 → 30/09/20

  Project: Research

• GRF: The Circadian Clock-dependent Cell-fate Decision of Adult Neural Stem Cells: How the Circadian Clock Controls Demyelination/Remyelination in the Brain

  KIM, J. Y. (Principal Investigator / Project Coordinator)

  1/01/20 → 11/06/24

  Project: Research

  • Circadian Rhythm 100%
  • Neural Stem Cell 62%
  • Remyelinization 40%
  • Subventricular Zone 36%
  • Mouse Brain 35%

• GRF: Development of Highly Versatile Oxygen-evolving Self-assembled Nanophotosensitizers for Photodynamic Eradication of Hypoxic Tumor

  LO, P. C. (Principal Investigator / Project Coordinator)

  1/01/20 → 25/06/24

  Project: Research

  • Neoplasm 100%
  • Tumor 93%
  • Phthalocyanine 78%
  • Catalase 72%
  • Photosensitizer 67%

• GRF: Investigating the Role of Thioredoxin-interacting Protein (Txnip) in Retinal Degeneration

  XIONG, W. (Principal Investigator / Project Coordinator)

  1/01/20 → 11/12/23

  Project: Research

  • Thioredoxin 100%
  • Retina Degeneration 100%
  • Thioredoxin Interacting Protein 100%
  • Photoreceptor Cell 86%
  • Lipoprotein Receptor-Related Protein 50%

• GRF: Self-assembly and Non-covalent Bonding of Siloxane Oligomers on Diverse Surfaces: from Molecular Mechanism to Advanced Coating Applications

  YAO, X. (Principal Investigator / Project Coordinator)

  1/01/20 → 6/12/23

  Project: Research

  • Polysiloxane 100%
  • Hydrogen Bonding 78%
  • Surface (Surface Science) 70%
  • Self Assembly 42%
  • Superhydrophobic 42%