Department of Biomedical Sciences

Projects

Projects per year 2005 2016 2018 2019 2021 2024 2026

• 11 Not started
• 151 Active
• 302 Finished

Projects per year

Search results

• Active

  ARD: Best Practices in Technology Transfer and Commercialization

  YANG, M. (Principal Investigator / Project Coordinator) & AI, C. D. (Co-Principal Investigator)

  1/07/05 → …

  Project: Research

  • Best Practice 100%
  • Commercialization 100%
  • Technology Transfer 100%
  • Industrial Policy 100%
  • Industry 100%
• Not started

  GRF: The Role of CEP250 in Regulating Macrophage Function During Atherosclerosis

  WANG, L. (Principal Investigator / Project Coordinator)

  1/01/26 → …

  Project: Research

• GRF: Investigation of the role of endothelial TGF-β2 in the development of atherosclerosis

  HUANG, Y. (Principal Investigator / Project Coordinator)

  1/01/26 → …

  Project: Research

• GRF: Roles of Lis1 in bone development and fracture repair

  MAK, K. L. K. (Principal Investigator / Project Coordinator)

  1/01/26 → …

  Project: Research

• GRF: Development of fibrous liquid-metal conductors with adaptive confinement of polymer network for stretchable electronic interconnects

  YAO, X. (Principal Investigator / Project Coordinator)

  1/01/26 → …

  Project: Research

• GRF: Cyanidin is a host signal for Pseudomonas syringas to regulate virulence and biofilm

  DENG, X. (Principal Investigator / Project Coordinator)

  1/01/26 → …

  Project: Research

• GRF: A multi-omics approach to study retinal pigment epithelium (RPE)-secreted factors in postnatal mouse eye size determination

  XIONG, W. (Principal Investigator / Project Coordinator)

  1/01/26 → …

  Project: Research

• GRF: Dissect mitochondrial extracellular vesicles in dermatomyositis

  ZHANG, L. (Principal Investigator / Project Coordinator)

  1/01/26 → …

  Project: Research

• ECS: Structural Information Theory and Its Applications to Spatiotemporal Dynamics in Spatial Transcriptomics

  CHEN, L. (Principal Investigator / Project Coordinator)

  1/01/26 → …

  Project: Research

• ECF: Environment and Conservation Fund - Establishing a Long-Term Air Quality Health Index Through Localised Scientific Evidence in Hong Kong

  LAO, X. (Principal Investigator / Project Coordinator) & LAU, A.K.-H. (Co-Investigator)

  1/09/25 → …

  Project: Research

• ITF: Repurposing and Formulating Alpha-2-macroglobulin (α2M) for Antiviral Treatment 

  HE, M. (Principal Investigator / Project Coordinator), CHAN, W. Y. R. (Co-Investigator), LI, A. M. (Co-Investigator) & YANG, M. (Co-Investigator)

  1/08/25 → …

  Project: Research

  • Alpha 2 Macroglobulin 100%
  • Safety Pharmacology 50%
  • Antivirus Agent 50%
  • Viral Skin Disease 50%
  • Repurposing 50%

• ITF: Development of Human Peripheral CAR-NK Cells to Treat Autoimmune Juvenile Dermatomyositis: Technology Innovation and Mechanistic Study

  ZHANG, L. (Principal Investigator / Project Coordinator) & HUANG, B. (Co-Investigator)

  1/08/25 → …

  Project: Research

  • Chimeric Antigen Receptor Natural Killer Cell 100%
  • Dermatomyositis 100%
  • Autoimmunity 50%
  • B Cell 28%
  • Antigen Specificity 7%
• Finished

  DON_RMG: Antiviral and Antitumor - RMGS

  HE, M. (Principal Investigator / Project Coordinator)

  1/07/23 → 5/03/24

  Project: Research

  • Antivirus Agent 100%
  • Diseases 100%
  • Malignant Neoplasm 66%
  • Heat Shock Protein 66%
  • Virus Infection 66%

• DON: Antiviral and Antitumor

  HE, M. (Principal Investigator / Project Coordinator)

  1/07/23 → 5/03/24

  Project: Research

• ITF: Development of a Non-viral Gene Therapy Platform for Retinal Degenerative Diseases

  XIONG, W. (Principal Investigator / Project Coordinator) & LO, P. C. (Co-Investigator)

  1/04/23 → 31/03/25

  Project: Research

• ITF: Development of Point-of-Care Testing Technology and Portable Device for Simultaneous Detection of Multiple Respiratory Tract Pathogens

  YANG, M. (Principal Investigator / Project Coordinator) & ZHAI, J. (Co-Investigator)

  1/02/23 → 31/01/25

  Project: Research

• ITF: Development of Damage-healable Structural-Color Material for Waterborne Wood Paints

  YAO, X. (Principal Investigator / Project Coordinator) & Li, M. (Co-Investigator)

  1/09/22 → 31/08/24

  Project: Research

  • Electronic Circuit 100%
  • Liquid Metal 89%
  • Ionic Liquid 59%
  • Soldering 59%
  • Conductor 59%

• ITF: Autologous-Allogeneic Human Peripheral CAK-NK Cells Construction and Combination with Immune Checkpoint Inhibitors on Treatment of Genitourinary Tumors: Key Technology Innovation, Efficacy and Mechanistic Study

  ZHANG, L. (Principal Investigator / Project Coordinator), CHO, C. S. (Co-Investigator), PENG, W. (Co-Investigator) & YUE, J. (Co-Investigator)

  1/08/22 → 31/01/25

  Project: Research

  • Endosome 100%
  • Flavivirus 65%
  • PD-L1 52%
  • Autophagy 52%
  • Tretinoin 52%

• ITF: Development and Pre-clinical Study of Externally Activated Nanomedicine for Anti-Cancer Therapy 

  YANG, M. (Principal Investigator / Project Coordinator), CHAN, W. Y. K. (Co-Investigator), LIN, D. (Co-Investigator), ZHAI, J. (Co-Investigator) & ZHAO, W. (Co-Investigator)

  1/03/22 → 28/02/25

  Project: Research

  • Vascularity 100%
  • Radioactive Tracer 100%
  • Drug Screening 100%
  • Metastatic Carcinoma 100%
  • Magnetic Nanoparticle 100%

• GRF: Overcoming the Intratumor Heterogeneity By Multi-Scale Spatial Characterizations of Tumor Microenvironment for Integrative Colorectal Cancer Classification

  WANG, X. (Principal Investigator / Project Coordinator)

  1/01/22 → 1/01/22

  Project: Research

  • MicroRNA 100%
  • Xenograft 83%
  • Cancer Classification 83%
  • Squamous Cell 83%
  • Cell Line 83%

• ITF: Development of a Novel Therapeutic to Promote Anticancer Immunity by Manipulating Endosomal Trafficking of PD-L1

  ZHANG, L. (Principal Investigator / Project Coordinator), CHO, W. (Co-Investigator), Wang, P. (Co-Investigator) & ZHU, K. (Co-Investigator)

  1/01/22 → 31/12/24

  Project: Research

  • Endosome 100%
  • CapZ 68%
  • Flavivirus 43%
  • Centrosome 34%
  • Lipid Droplet 34%

• GRF: Evolution of Virulence Plasmids and Their Role in Clinical Adaptation and Virulence Expression of ST11 Carbapenem-Resistant Klebsiella Pneumoniae

  CHEN, S. (Principal Investigator / Project Coordinator) & DENG, X. (Co-Investigator)

  1/01/22 → 1/03/23

  Project: Research

  • Klebsiella pneumoniae 100%
  • Virulence Plasmid 46%
  • Plasmid 39%
  • Antimicrobial Resistance 37%
  • Infectious Agent 22%

• HMRF: Comparing Dengue Mosquito Predictivity of Gravitrap to Ovitrap Surveillance Systems Using Weather Data in Hong Kong

  YUAN, H.-Y. S. (Principal Investigator / Project Coordinator)

  1/11/21 → 18/10/24

  Project: Research

• DON_RMG: Generation of Induced-pluripotent Stem Cells (iPSCs) of Small Animals for Veterinary Regenerative Medicine - RMGS

  GO, Y. Y. (Principal Investigator / Project Coordinator) & BAN, K. (Co-Investigator)

  1/08/21 → 27/02/23

  Project: Research

• AoE(UGC)-ExtU-Lead: Centre for Medical Engineering of Molecular and Biological Probes

  Wong, N. (Main Project Coordinator [External]) & WANG, X. (Principal Investigator / Project Coordinator)

  1/06/21 → 31/10/21

  Project: Research

  • MicroRNA 100%
  • Ferroptosis 32%
  • Macrophage 32%
  • Tamsulosin 32%
  • Aptamer 32%

• SZOth-SRI: 剧毒卡尔藻释放的化感物质及其对东海原甲藻的抑制机理研究

  WANG, R. (Principal Investigator / Project Coordinator)

  1/04/21 → 31/03/24

  Project: Research

• ASDC_Sub: Development of Coordination-driven Supramolecular Nanoplatforms for Theranostic Applications

  LO, P. C. (Principal Investigator / Project Coordinator)

  28/02/21 → 15/04/24

  Project: Research

  • Tumor 100%
  • Hydrogen Peroxide 100%
  • Nanosystems 100%
  • Nanoparticle 100%
  • Glutathione 33%

• ASDC_Sub: Characterization of Key regulators of Pseudomonas Aeruginosa Virulence

  DENG, X. (Principal Investigator / Project Coordinator)

  28/02/21 → 15/04/24

  Project: Research

  • Transcription Factors 100%
  • Pseudomonas aeruginosa 100%
  • Regulatory Network 50%
  • Type III Secretion System 16%
  • Type VI Secretion System 16%

• ASDC_Sub: Neural Cell Networking Mediated by Circadian Clocks to Enhance Brain Repair Systems

  KIM, J. Y. (Principal Investigator / Project Coordinator)

  28/02/21 → 15/04/24

  Project: Research

  • Circadian Rhythm 100%
  • Hypertonic Solution 50%
  • Catenin 50%
  • Nervous System Development 50%
  • Transcription Factors 50%

• ITF: Biosensors for the Rapid Identification of Clinically Important Microorganisms

  LAM, Y. W. (Principal Investigator / Project Coordinator), LAM, H. W. M. (Co-Investigator) & LAU, C. K. T. (Co-Investigator)

  1/02/21 → 18/09/22

  Project: Research

• ASDC_Sub: Developing Gene Editing Therapy for Inherited Retinal Diseases

  XIONG, W. (Principal Investigator / Project Coordinator)

  1/02/21 → 26/02/25

  Project: Research

• ASDC_Sub: Development of 3D Organoid Models for Identifying Novel Breast Cancer Therapeutics Targeting Tumor Microenvironment and Cancer Stem Cells

  CHIN, R. Y. M. (Principal Investigator / Project Coordinator)

  1/02/21 → 15/04/24

  Project: Research

  • Protein Kinase B 100%
  • Upregulation 50%
  • Protein Tyrosine Kinase 50%
  • Protein Kinase B Inhibitor 50%
  • Breast Cancer 50%

• CRF: A Universal Solid/liquid-Based Framework for Efficient Water Energy Harvesting

  WANG, Z. (Principal Investigator / Project Coordinator), Qian, T. (Co-Principal Investigator), WANG, L. (Co-Principal Investigator), XU, L. (Co-Principal Investigator), YANG, Z. (Co-Principal Investigator), YAO, X. (Co-Principal Investigator) & Yao, S. (Co-Principal Investigator)

  1/02/21 → 2/02/23

  Project: Research

  • Surface (Surface Science) 100%
  • Power Generation 25%
  • Energy Harvesting 25%
  • Elastic Energy 20%
  • Surface Design 19%

• ASDC_Sub: Exploring the Molecular Mechanisms of HERV-H in Mediating Chromatin High-order Structure in Human Embryonic Stem Cells

  YAN, J. (Principal Investigator / Project Coordinator)

  1/02/21 → 15/04/24

  Project: Research

• ASDC_Sub: Screen for Molecular Targets in the Senescence Response of Tumor Cells to Chemotherapy

  ZHANG, L. (Principal Investigator / Project Coordinator)

  1/02/21 → 15/04/24

  Project: Research

  • Proteomics 100%
  • Wnt Signaling Pathway 86%
  • Hypertonic Solution 80%
  • Proteome 80%
  • Tumor Necrosis Factor 80%

• ASDC_Sub: TLR Agonists as Plasmacytoid Dendritic Cell-based Cancer Immunotherapy

  CHOW, K. T. (Principal Investigator / Project Coordinator)

  1/02/21 → 15/04/24

  Project: Research

  • Malignant Neoplasm 100%
  • Nitric Oxide 100%
  • Photosensitizer 100%
  • Photodynamic Therapy 100%
  • Recurrent Disease 100%

• ASDC_Sub: Delivery of sRNA to Target Drug Resistant Bacteria

  LAU, C. K. T. (Principal Investigator / Project Coordinator)

  1/02/21 → 15/04/24

  Project: Research

  • Antibiotics 100%
  • Nanodiamond 100%
  • Urinary Tract Infection 100%
  • Recurrent Disease 100%
  • Intracellular Bacterium 100%

• ASDC_Sub: Intergrative Analysis of Multi-omics and Histopathology Images to Establish a Classification System for Esophageal Squamous Cell Cacinoma

  WANG, X. (Principal Investigator / Project Coordinator)

  1/02/21 → 28/04/22

  Project: Research

• GRF: Mechanistic Studies of CapZβ Signaling in the Maturation of Early Endosomes

  CHAN, K. M. (Principal Investigator / Project Coordinator) & YUE, J. (Co-Investigator)

  1/01/21 → 17/12/24

  Project: Research

  • Capping Phenomenon 100%
  • Endosome 100%
  • Malignant Neoplasm 81%
  • Protein Z 75%
  • Autophagy 75%

• GRF: Inter-regional Communication Mechanisms Mediated by Circadian Clocks in Pathological Conditions of the Brain

  KIM, J. Y. (Principal Investigator / Project Coordinator)

  1/01/21 → 12/06/25

  Project: Research

  • Circadian Rhythm 100%
  • Brain Areas 31%
  • Neurodegeneration 27%
  • Mouse Brain 27%
  • Neurogenesis 27%

• GRF: Concerted Activation of Photosensitizers and Release of Anticancer Drugs Through Tetrazine-Induced Bioorthogonal Decaging Reactions

  LO, P. C. (Principal Investigator / Project Coordinator) & NG, K. P. D. (Co-Investigator)

  1/01/21 → 24/06/25

  Project: Research

  • Photosensitizer 100%
  • Tetrazine 100%
  • Neoplasm 77%
  • Anticancer Drug 66%
  • Antineoplastic Agent 66%

• GRF: Endothelial Cell Nrf2 Activation Inhibits Atherosclerosis

  HUANG, Y. (Principal Investigator / Project Coordinator)

  1/01/21 → 17/12/24

  Project: Research

  • Atherosclerosis 100%
  • Endothelial Cell 80%
  • Inflammation 77%
  • Transcription Factor Nrf2 56%
  • Vascular Disease 41%

• GRF: Developing High-strength Supramolecular Adhesives with Controlled Liquid Inclusion: from Mechanistic Study to Antibacterial Applications

  YAO, X. (Principal Investigator / Project Coordinator)

  1/01/21 → 23/12/24

  Project: Research

  • Hydrogel 100%
  • Surface (Surface Science) 89%
  • Hydrogen Bonding 63%
  • Ionic Liquid 60%
  • Biomedical Application 53%

• GRF: Revealing Signaling Pathway of Novel Two-component System TsiRS in Regulating Virulence of Pseudomonas Syringae

  DENG, X. (Principal Investigator / Project Coordinator) & Ji, Q. (Co-Investigator)

  1/01/21 → 8/02/24

  Project: Research

  • Pseudomonas syringae 100%
  • Type Three Secretion System 63%
  • Transcription Factors 40%
  • Type III Secretion System 32%
  • Regulatory Network 30%

• GRF: Health Effects of Neighborhood Walkability on Chinese Adults: Analysis of an Existing Longitudinal Cohort

  LAO, X. (Principal Investigator / Project Coordinator), Guo, C. (Co-Investigator), RUDGE, G. (Co-Investigator) & THOMAS, G. N. (Co-Investigator)

  1/01/21 → 12/06/25

  Project: Research

  • Proportional Hazards Model 100%
  • Regression Model 100%
  • Mediation Analysis 94%
  • Three-Dimension 94%
  • Generalized Linear Mixed Model 94%

• NSFC-GP-SRI: Zswim4在骨骼发育及再生中的功能和机制研究

  MAK, K. L. K. (Principal Investigator / Project Coordinator)

  1/01/21 → 31/12/24

  Project: Research

• ITF: Precision Prediction Models for COVID-19

  CHAN, K. H. K. (Principal Investigator / Project Coordinator)

  1/12/20 → 31/05/22

  Project: Research

  • Random Forest 100%
  • Biological Marker 100%
  • COVID-19 100%
  • COVID-19 Mortality 100%
  • Electronic Medical Record 50%

• HMRF: Modelling of Hong Kong COVID-19 Control Strategies Considering Different Population Immunity Scenarios

  YUAN, H.-Y. S. (Principal Investigator / Project Coordinator), PFEIFFER, D. U. (Co-Investigator), QIN, S. J. (Co-Investigator), WANG, X. (Co-Investigator) & ZHANG, Q. (Co-Investigator)

  1/11/20 → 24/04/24

  Project: Research

  • COVID-19 100%
  • Infection 45%
  • Observational Study 32%
  • Social Distancing 25%
  • Non-Pharmaceutical Intervention 24%

• ITF-ExtU-Lead: COVID-19 Detection based on Fluorescence Polarization Measurement

  YANG, M. (Principal Investigator / Project Coordinator)

  1/11/20 → 31/10/21

  Project: Research

• HMRF: Selective PPARα Activation Directly Protects Vascular Function through Inhibition of YAP/TAZ-Mediated Oxidative Stress and Inflammation

  HUANG, Y. (Principal Investigator / Project Coordinator), Luo, J.-Y. (Co-Investigator) & Tomlinson, B. (Co-Investigator)

  15/09/20 → 24/04/24

  Project: Research

  • Inflammation 100%
  • Atherosclerosis 58%
  • Atherogenesis 55%
  • Endothelial Cell 46%
  • Endothelial Dysfunction 45%