Department of Biomedical Sciences

Projects

Projects per year 2005 2016 2018 2019 2021 2024 2026

• 11 Not started
• 151 Active
• 302 Finished

Projects per year

Search results

• Active

  HMRF: Patient-derived Organoid Platform for Evaluating Drug Sensitivity and Identifying Long Noncoding RNA LINC01235 as A New RNA Therapeutics to Overcome Chemoresistance in Breast Cancer

  CHIN, R. Y. M. (Principal Investigator / Project Coordinator), TSE, G. (Co-Investigator) & WANG, X. (Co-Investigator)

  1/07/25 → …

  Project: Research

  • Long Noncoding RNA 100%
  • RNA 100%
  • Drug Resistance 100%
  • Drug Sensitivity 100%
  • Drug Screening 33%

• CRF: A High-performance Mass Spectrometry Platform for Next-generation Proteomics and Metabolomics

  ZHANG, L. (Principal Investigator / Project Coordinator), LAI, K. O. (Co-Principal Investigator), NG, C. F. (Co-Principal Investigator), SUN, H. (Co-Principal Investigator), XIA, J. (Co-Principal Investigator), YAN, J. (Co-Principal Investigator), YANG, M. (Co-Principal Investigator), Yao, Z. (Co-Principal Investigator), YIN, H. (Co-Principal Investigator) & ZHAO, Q. (Co-Principal Investigator)

  30/06/25 → …

  Project: Research

• CRF: Long-term Rescuing Effects on Remembering and Memory Retention in Alzheimer’s Disease Mice with Self-synthesized CCK-B Receptor Agonists

  HE, J. (Principal Investigator / Project Coordinator), CHEN, X. (Co-Principal Investigator), LAI, S. W. C. (Co-Principal Investigator), LI, Y. (Co-Principal Investigator), TORTORELLA, M. D. (Co-Principal Investigator) & YANG, S. (Co-Principal Investigator)

  30/06/25 → …

  Project: Research

• CRF-Sub-pj: Long-term Rescuing Eff ects on Remembering and Memory Retention in Alzheimer’s Disease Mice with Self-synthesized CCK-B Receptor Agonists

  CHEN, X. (Principal Investigator / Project Coordinator)

  30/06/25 → …

  Project: Research

• RIF: Uncovering Dynamically Functional Cells Using a Time-Resolved Intelligent Cell Sorter (TRIC) for Cancer Treatments

  CHEN, C.-H. (Principal Investigator / Project Coordinator), LEE, V. H. F. (Co-Principal Investigator), REN, H. (Co-Principal Investigator) & ZHANG, L. (Co-Principal Investigator)

  1/06/25 → …

  Project: Research

  • Cancer Therapy 100%

• CRF-ExtU-Lead: Advancing Photodynamic Therapy against Cancer through Bioorthogonal and SupramolecularApproaches

  NG, K. P. D. (Main Project Coordinator [External]), CHOW, K. T. (Principal Investigator / Project Coordinator), LO, P. C. (Co-Principal Investigator), MA, B. B. Y. (Co-Principal Investigator) & TONG, M. C. (Co-Principal Investigator)

  1/06/25 → …

  Project: Research

• CRF-ExtU-Lead: Advancing Photodynamic Therapy against Cancer through Bioorthogonal and Supramolecular Approaches

  NG, K. P. D. (Main Project Coordinator [External]), LO, P. C. (Principal Investigator / Project Coordinator), CHOW, K. T. (Co-Principal Investigator), MA, B. B. Y. (Co-Principal Investigator) & TONG, M. C. (Co-Principal Investigator)

  1/06/25 → …

  Project: Research

• CRF-Sub-pj: Cell Intrinsic and Extrinsic Effects of Astrocytes Lipid Metabolism in Spinal Muscular

  YIN, H. (Principal Investigator / Project Coordinator)

  1/06/25 → …

  Project: Research

• SSF-CityUHK: AI-assisted High-Throughput Identification of Natural and Synthetic Bioactive Peptides with Clinical Potential

  HUANG, Y. (Principal Investigator / Project Coordinator), MA, J. (Co-Principal Investigator), WANG, L. (Co-Principal Investigator), WENG, J. (Co-Principal Investigator), CHEN, L. (Co-Investigator) & ZHANG, E. L. (Co-Investigator)

  1/06/25 → …

  Project: Research

• REG-Small Scale: AI-Assisted High-Throughput Platform for Functional Peptide Discovery and Characterization

  WANG, L. (Principal Investigator / Project Coordinator) & MA, J. (Co-Investigator)

  1/06/25 → …

  Project: Research

• CRF: Cell Intrinsic and Extrinsic Effects of Astrocytes Lipid Metabolism in Spinal Muscular

  LIU, A. J. (Principal Investigator / Project Coordinator), CHAN, H. S. S. (Co-Principal Investigator), CHEUNG, C. H. M. (Co-Principal Investigator), HUANG, Y. (Co-Principal Investigator), YIN, H. (Co-Principal Investigator), HUI, C.-C. (Co-Investigator) & JAMES, B. (Co-Investigator)

  1/06/25 → …

  Project: Research

• ITF: Construction and Clinical Application of Monosperm Biochemical Sorting Microfluidic System Based On Intelligent Conversion Hydrogel Material

  YANG, M. (Principal Investigator / Project Coordinator) & ZHOU, X. (Co-Investigator)

  1/02/25 → …

  Project: Research

  • Fertilization 100%

• GRF: ALDOB Modulates Beta-Cell Insulin Secretion in Diabetes Through Insulin Receptor Pathways 

  YIN, H. (Principal Investigator / Project Coordinator)

  1/01/25 → …

  Project: Research

  • Insulin Release 100%
  • Insulin Receptor 100%
  • Metabolomics 58%
  • Downregulation 50%
  • Uncoupling Protein 50%

• GRF: Endothelial TFEB Activation Inhibits Hypoxia-Induced Pulmonary Hypertension 

  HUANG, Y. (Principal Investigator / Project Coordinator) & WANG, L. (Co-Investigator)

  1/01/25 → …

  Project: Research

  • Hypoxia-Induced Pulmonary Hypertension 100%
  • Pulmonary Hypertension 100%
  • Transcription Factors 100%
  • Endothelial Dysfunction 25%
  • Sleep Disordered Breathing 8%

• TDG(CityU): GeneBox: an interactive app for teaching and learning biology

  LIDSKY, P. V. (Principal Investigator / Project Coordinator), MAK, K. L. K. (Co-Investigator) & WANG, L. (Co-Investigator)

  1/01/25 → …

  Project: Research

  • Molecular Biology 100%
  • Gene Regulatory Network 100%
  • Genetics 100%

• NSFC-YPC-SRI: E2F2在动脉粥样硬化血管内皮功能损伤中的作用与机制研究

  WU, Y. (Principal Investigator / Project Coordinator)

  1/01/25 → …

  Project: Research

• SZSMRF-SRI: 基于癌症诊断前血液样本的多肿瘤液体活检标志物研究

  ZHENG, Z. (Principal Investigator / Project Coordinator)

  1/01/25 → …

  Project: Research

• GDBAB-NSF-HK: 基於高導電聚離子液體複合膜的濕度發電研究

  YAO, X. (Principal Investigator / Project Coordinator)

  1/01/25 → …

  Project: Research

• STG-ExtU-Lead: Personalized Rehabilitation Pathways to Maximal Motor Functional Return through an AI Recovery Prediction System for Diverse Stroke Survivors

  CHEUNG, C. K. V. (Main Project Coordinator [External]) & CHAN, K. H. K. (Principal Investigator / Project Coordinator)

  1/01/25 → …

  Project: Research

• NSFC-YPC-HK: Integrated Spatial Transcriptome Analysis and Algorithms for AI-Enabled Cancer Diagnosis

  CHEN, L. (Principal Investigator / Project Coordinator)

  1/01/25 → …

  Project: Research

• SZNSFC-GP-SRI: 精神障碍的药物再利用

  CHAN, K. H. K. (Principal Investigator / Project Coordinator)

  27/11/24 → …

  Project: Research

• SZNSFC-GP-SRI: 高拉伸可焊接的液态金属聚合物复合材料的界面工程研究

  YAO, X. (Principal Investigator / Project Coordinator), 强梦怡 (Co-Investigator), 李鑫 (Co-Investigator), 王晓雅 (Co-Investigator) & 王雪娇 (Co-Investigator)

  27/11/24 → …

  Project: Research

• DON-JC(F): Highly Integrated Tumor Microenvironment 3D Microfluidic Device for High Throughput Drug Screening and Studying Cancer Metastasis 

  YANG, M. (Principal Investigator / Project Coordinator) & YANG, Z. (Co-Investigator)

  1/09/24 → …

  Project: Research

• ITF: Development of Cadherin-17-Targeted Antibody-Drug Conjugates for the Treatment of Advanced Gastrointestinal Cancers

  LO, P. C. (Principal Investigator / Project Coordinator), NG, K. P. D. (Co-Investigator) & WONG, K. F. (Co-Investigator)

  1/09/24 → …

  Project: Research

• STDSP-CGLSTDP-CRI: DNA甲基化调控丁香假单胞菌适应性和毒力的分子机理研究

  DENG, X. (Principal Investigator / Project Coordinator)

  1/09/24 → …

  Project: Research

• DON-JC(F): Highly Integrated Tumor Microenvironment 3D Microfluidic Device for High Throughput Drug Screening and Studying Cancer Metastasis (Seed Funding)

  YANG, Z. (Principal Investigator / Project Coordinator) & YANG, M. (Co-Investigator)

  1/09/24 → …

  Project: Research

• DON_RMG: IDM Cluster 1: Biomarkers, Diagnostics and Therapeutics - RMGS

  ZHANG, Y. (Principal Investigator / Project Coordinator) & YIN, H. (Co-Principal Investigator)

  1/09/24 → …

  Project: Research

  • Nanomaterial 100%
  • Output Signal 75%
  • Energy Source 50%
  • Progression 25%
  • Energy Conversion 25%

• TDG(CityU): Enhancing Statistics Learning for Biology Students: Leveraging Technology for Motivation and Engagement

  CHAN, K. H. K. (Principal Investigator / Project Coordinator)

  19/08/24 → …

  Project: Research

  • Artificial Intelligence 100%
  • Chatbot 50%
  • Project Plan 50%

• RIF-ExtU-Lead: Development of Liquid Biopsy Assays based on Exosomal Small Non-Coding RNAs for Non-Invasive Early Detection of Pancreatic Cancer

  WANG, X. (Main Project Coordinator [External]) & CHAN, K. M. (Principal Investigator / Project Coordinator)

  30/06/24 → …

  Project: Research

• CRF-Sub-pj: Controllable Activation of Anticancer Prodrugs in vivo

  HE, M. (Principal Investigator / Project Coordinator)

  30/06/24 → …

  Project: Research

• CRF: Controllable Activation of Anticancer Prodrugs in vivo

  ZHU, G. (Principal Investigator / Project Coordinator), BABAK, M. (Co-Principal Investigator), HE, M. (Co-Principal Investigator), KONG, F.-M. S. (Co-Principal Investigator), SUN, J. (Co-Principal Investigator), ZHANG, W. (Co-Principal Investigator) & CHEN, X. (Collaborator)

  30/06/24 → …

  Project: Research

  • Proteolysis 100%
  • Protein Catabolism 100%
  • Cysteine 100%
  • Prodrug 100%
  • Bioluminescence 75%

• DON_RMG: Planning and Implementation of Institute of Digital Medicine (IDM) at City University of Hong Kong (CityUHK) - RMGS

  YANG, M. (Principal Investigator / Project Coordinator)

  1/05/24 → …

  Project: Research

  • Nanomaterial 100%
  • Output Signal 75%
  • Energy Source 50%
  • Progression 25%
  • Energy Conversion 25%

• ASDC_Sub: Futian Research Project: Regulation of Brain Metastatic Colonization of Triple-Negative Breast Cancer by Novel Genes

  CHIN, R. Y. M. (Principal Investigator / Project Coordinator) & LO, P. C. (Co-Investigator)

  1/04/24 → …

  Project: Research

  • FOSL1 100%
  • Enhancer Region 100%
  • Tubulin 100%
  • Beta Tubulin 100%
  • Triple Negative Breast Cancer 100%

• ASDC_Sub: Futian Research Project: Automated Droplet Screen System for Rapid Single-Cell Immune Response Assessment

  CHEN, C.-H. (Principal Investigator / Project Coordinator) & ZHANG, L. (Co-Investigator)

  1/04/24 → …

  Project: Research

• ASDC_Sub: Futian Research Project: Understanding How Sleep Disturbance Affects Clock Functions in the Hippocampus and Its Consequences

  KIM, J. Y. (Principal Investigator / Project Coordinator) & ZHANG, L. (Co-Investigator)

  1/04/24 → …

  Project: Research

• ASDC_Sub: Futian Research Project: Single-Cell Metabolomics: Towards Applications in Cancer and Aging 

  YIN, H. (Principal Investigator / Project Coordinator), YANG, M. (Co-Investigator) & ZHANG, L. (Co-Investigator)

  1/04/24 → …

  Project: Research

  • Demethylation 100%
  • Histone Deacetylase 100%
  • Prospective Study 100%
  • Metabolite 100%
  • Metabolomics 100%

• ASDC_Sub: Futian Research Project: Develop Chemical Biology Tools to Dissect SIRT3 Functions and Mitochondrial Homeostasis of Cancer Cells

  ZHANG, L. (Principal Investigator / Project Coordinator) & SUN, H. (Co-Investigator)

  1/04/24 → …

  Project: Research

  • Steady State 100%
  • Light Dark Cycle 100%
  • Prochlorococcus 100%
  • Proteome 100%
  • Proteomics 100%

• ASDC_Sub: Futian Research Project: Development of Novel Molecular and Nano-Sensitizers for Sonodynamic Therapy

  LO, P. C. (Principal Investigator / Project Coordinator) & CHOW, K. T. (Co-Investigator)

  1/04/24 → …

  Project: Research

• ASDC_Sub: Futian Research Project: Investigation of Therapeutic Potential of Exosomes Derived from hiPSCs for Treating Hair Loss Patients

  BAN, K. (Principal Investigator / Project Coordinator) & LO, P. C. (Co-Investigator)

  1/04/24 → …

  Project: Research

  • Reactive Oxygen Metabolite 100%
  • Myocardial Ischemia Reperfusion Injury 100%
  • Reperfusion Injury 100%
  • Ethyl Acetate 50%
  • Hydrogen Peroxide 25%

• ASDC_Sub: Futian Research Project: Genome-Wide Characterization of Virulence-Related and Antibiotic-Resistance Related Hypothetical Proteins in Pseudomonas aeruginosa

  DENG, X. (Principal Investigator / Project Coordinator) & YAN, J. (Co-Investigator)

  1/04/24 → …

  Project: Research

• ASDC_Sub: Futian Research Project: Development of Targeted Tumor-Mimicking Nanoparticles for Chemotherapeutic Drug Delivery and Modulation of the Glioblastoma Immune Microenvironment

  WANG, D. (Principal Investigator / Project Coordinator) & ZHENG, Z. (Co-Investigator)

  1/04/24 → …

  Project: Research

  • Tissue Regeneration 100%
  • Regeneration 58%
  • Collagen Type 2 50%
  • Cell Membrane 50%
  • Vascular Endothelial Cell 50%

• ASDC_Sub: Futian Research Project: Natural Herb Compounds for Prevention of Skin Ageing

  HE, M. (Principal Investigator / Project Coordinator) & ZHU, L. (Co-Investigator)

  1/04/24 → …

  Project: Research

• ASDC_Sub: Futian Research Project: A Single-Cell Platform to Investigate the Metabolism of NK and Cancer Cells in CAR-NK Therapy

  ZHANG, L. (Principal Investigator / Project Coordinator) & ZHOU, X. (Co-Investigator)

  1/04/24 → …

  Project: Research

  • Steady State 100%
  • Light Dark Cycle 100%
  • Prochlorococcus 100%
  • Proteome 100%
  • Proteomics 100%

• ASDC_Sub: Futian Research Project: CEST MRI for Assessing Molecular Abnormalities in Aging Brain

  CHAN, W. Y. K. (Principal Investigator / Project Coordinator), LEE, Y. (Co-Investigator), YIN, H. (Co-Investigator) & ZHAO, X. (Co-Investigator)

  1/04/24 → …

  Project: Research

  • Chemical Exchange Saturation Transfer 100%
  • In Vivo 100%
  • Contrast Medium 100%
  • Nanocarriers 100%
  • Nanocarrier 100%

• ASDC_Sub: Futian Research Project: Building AI-Enabled Cancer Diagnostic Model With Ligand-Receptor Interaction Biomarkers Through Spatial Transcriptome

  CHEN, L. (Principal Investigator / Project Coordinator) & YANG, M. (Co-Investigator)

  1/04/24 → …

  Project: Research

  • Mitochondrion 100%
  • Neoplasm 100%
  • T Cell 100%
  • RNA Sequence 100%
  • Cancer Cell 33%

• ASDC_Sub: Futian Research Project: Develop a Medical Diagnostic Approach Based on the Altered RNA-RBP Binding Dynamics

  ZHANG, J. (Principal Investigator / Project Coordinator), DENG, X. (Co-Investigator), FU, B. (Co-Investigator) & YAN, J. (Co-Investigator)

  1/04/24 → …

  Project: Research

• ASDC_Sub: Futian Research Project: Identification of Noncoding RNA Driving Epigenetic Changes During Cellular Senescence

  YAN, J. (Principal Investigator / Project Coordinator) & ZHANG, J. (Co-Investigator)

  1/04/24 → …

  Project: Research

• ASDC_Sub: Futian Research Project: Elucidating the Mechanisms and Therapeutic Potential of Photodynamic Therapy in Wound Healing

  CHOW, K. T. (Principal Investigator / Project Coordinator) & LO, P. C. (Co-Investigator)

  1/04/24 → …

  Project: Research

  • Ecalectin 100%
  • Cancer Prognosis 100%
  • Meta-Analysis 100%
  • Malignant Neoplasm 57%
  • Hazard Ratio 28%

• ASDC_Sub: Futian Research Project: Using DNA Methylation for Acute Myeloid Leukemia Subtyping

  LI, R. (Principal Investigator / Project Coordinator) & ZHANG, L. (Co-Investigator)

  1/04/24 → …

  Project: Research

• ASDC_Sub: Futian Research Project: High-Fidelity Microscopy Investigations of Eye Diseases

  ZHANG, Q. (Principal Investigator / Project Coordinator) & XIONG, W. (Co-Investigator)

  1/04/24 → …

  Project: Research