Journal of Medicinal Chemistry

Journal of Medicinal Chemistry

ISSNs: 0022-2623, 0095-9065, 1520-4804

American Chemical Society, United States

Scopus rating (2021): CiteScore 11.5 SJR 1.888 SNIP 1.841

Journal

Journal Metrics

Research Output

  1. 2021
  2. Published

    Dual Cathepsin B and Glutathione-Activated Dimeric and Trimeric Phthalocyanine-Based Photodynamic Molecular Beacons for Targeted Photodynamic Therapy

    Tam, L. K. B., Yu, L., Wong, R. C. H., Fong, W., Ng, D. K. P. & Lo, P., 9 Dec 2021, In: Journal of Medicinal Chemistry. 64, 23, p. 17455–17467

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 2
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  3. Published

    Novel Electrophilic Warhead Targeting a Triple-Negative Breast Cancer Driver in Live Cells Revealed by "inverse Drug Discovery"

    Fan, Y., Si, H., Zhang, Z., Zhong, L., Sun, H., Zhu, C., Yin, Z. & 7 others, Li, H., Tang, G., Yao, S. Q., Sun, P., Zhang, Z., Ding, K. & Li, Z., 11 Nov 2021, In: Journal of Medicinal Chemistry. 64, 21, p. 15582–15592

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 1
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  4. 2020
  5. Published

    Methylation of Daptomycin Leading to the Discovery of Kynomycin, a Cyclic Lipodepsipeptide Active against Resistant Pathogens

    Chow, H. Y., Po, K. H. L., Gao, P., Blasco, P., Wang, X., Li, C., Ye, L. & 7 others, Jin, K., Chen, K., Chan, E. W. C., You, X., Yi Tsun Kao, R., Chen, S. & Li, X., 26 Mar 2020, In: Journal of Medicinal Chemistry. 63, 6, p. 3161-3171

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 17
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  6. 2019
  7. New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action

    Ohui, K., Afanasenko, E., Bacher, F., Ting, R. L. X., Zafar, A., Blanco-Cabra, N., Torrents, E. & 10 others, Dömötör, O., May, N. V., Darvasiova, D., Enyedy, É. A., Popović-Bijelić, A., Reynisson, J., Rapta, P., Babak, M. V., Pastorin, G. & Arion, V. B., 24 Jan 2019, In: Journal of Medicinal Chemistry. 62, 2, p. 512-530

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 51
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  8. 2018
  9. Published

    Endoplasmic Reticulum-Localized Two-Photon-Absorbing Boron Dipyrromethenes as Advanced Photosensitizers for Photodynamic Therapy

    Zhou, Y., Cheung, Y., Ma, C., Zhao, S., Gao, D., Lo, P., Fong, W. & 2 others, Wong, K. S. & Ng, D. K. P., 10 May 2018, In: Journal of Medicinal Chemistry. 61, 9, p. 3952-3961

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 40
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  10. 2017
  11. Published

    A Rhodium(III)-Based Inhibitor of Lysine-Specific Histone Demethylase 1 as an Epigenetic Modulator in Prostate Cancer Cells

    Yang, C., Wang, W., Liang, J., Li, G., Vellaisamy, K., Wong, C., Ma, D. & 1 others, Leung, C., 23 Mar 2017, In: Journal of Medicinal Chemistry. 60, 6, p. 2597-2603

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 52
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  12. 2014
  13. A dual activatable photosensitizer toward targeted photodynamic therapy

    Lau, J. T. F., Lo, P., Jiang, X., Wang, Q. & Ng, D. K. P., 22 May 2014, In: Journal of Medicinal Chemistry. 57, 10, p. 4088-4097

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 97
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  14. 2013
  15. Preparation and in vitro photodynamic activities of folate-conjugated distyryl boron dipyrromethene based photosensitizers

    Ke, M., Yeung, S., Ng, D. K. P., Fong, W. & Lo, P., 14 Nov 2013, In: Journal of Medicinal Chemistry. 56, 21, p. 8475-8483

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 73
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  16. 2012
  17. A zinc(II) phthalocyanine conjugated with an oxaliplatin derivative for dual chemo- and photodynamic therapy

    Lau, J. T. F., Lo, P., Fong, W. & Ng, D. K. P., 14 Jun 2012, In: Journal of Medicinal Chemistry. 55, 11, p. 5446-5454

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 93
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  18. 2011
  19. Synthesis and in vitro photodynamic activities of pegylated distyryl boron dipyrromethene derivatives

    He, H., Lo, P., Yeung, S., Fong, W. & Ng, D. K. P., 28 Apr 2011, In: Journal of Medicinal Chemistry. 54, 8, p. 3097-3102

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 60
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  20. Phthalocyanine-polyamine conjugates as highly efficient photosensitizers for photodynamic therapy

    Jiang, X., Yeung, S., Lo, P., Fong, W. & Ng, D. K. P., 13 Jan 2011, In: Journal of Medicinal Chemistry. 54, 1, p. 320-330

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 117
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  21. 2009
  22. Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers

    Lo, P., Chen, J., Stefflova, K., Warren, M. S., Navab, R., Bandarchi, B., Mullins, S. & 3 others, Tsao, M., Cheng, J. D. & Zheng, G., 22 Jan 2009, In: Journal of Medicinal Chemistry. 52, 2, p. 358-368

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 94
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  23. 2008
  24. Published

    Surprising alteration of antibacterial activity of 5″-modified neomycin against resistant bacteria

    Zhang, J., Chiang, F., Wu, L., Czyryca, P. G., Li, D. & Chang, C. T., 11 Dec 2008, In: Journal of Medicinal Chemistry. 51, 23, p. 7563-7573

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 76
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  25. Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain

    Irie, O., Kosaka, T., Ehara, T., Yokokawa, F., Kanazawa, T., Hirao, H., Iwasaki, A. & 16 others, Sakaki, J., Teno, N., Hitomi, Y., Iwasaki, G., Fukaya, H., Nonomura, K., Tanabe, K., Koizumi, S., Uchiyama, N., Bevan, S. J., Malcangio, M., Gentry, C., Fox, A. J., Yaqoob, M., Culshaw, A. J. & Hallett, A., 25 Sep 2008, In: Journal of Medicinal Chemistry. 51, 18, p. 5502-5505

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 31
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  26. 2007
  27. Highly photocytotoxic glucosylated silicon(IV) phthalocyanines. Effects of peripheral chloro substitution on the photophysical and photodynamic properties

    Lo, P., Chan, C. M. H., Liu, J., Fong, W. & Ng, D. K. P., 3 May 2007, In: Journal of Medicinal Chemistry. 50, 9, p. 2100-2107

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 92
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  28. 2006
  29. Synthesis and biological evaluation of purealin and analogues as cytoplasmic dynein heavy chain inhibitors

    Zhu, G., Yang, F., Balachandran, R., Höök, P., Vallee, R. B., Curran, D. P. & Day, B. W., 23 Mar 2006, In: Journal of Medicinal Chemistry. 49, 6, p. 2063-2076

    Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

    Scopus citations: 37
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