Journal of Medicinal Chemistry

Journal of Medicinal Chemistry

ISSNs: 0022-2623, 0095-9065, 1520-4804

American Chemical Society, United States

Scopus rating (2023): CiteScore 12.8 SJR 1.986 SNIP 1.594

Journal

Journal Metrics
1 - 17 out of 17Page size: 20

Research Output

  1. 2022
  2. Published

    Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors

    Li, S., Zhang, P., Xu, F., Hu, S., Liu, J., Tan, Y., Tu, Z., & 6 othersSun, H., Zhang, Z., He, Q., Sun, P., Ding, K. & Li, Z., 11 Aug 2022, In: Journal of Medicinal Chemistry. 65, 15, p. 10408–10418

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 14
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  3. 2021
  4. Published

    Dual Cathepsin B and Glutathione-Activated Dimeric and Trimeric Phthalocyanine-Based Photodynamic Molecular Beacons for Targeted Photodynamic Therapy

    Tam, L. K. B., Yu, L., Wong, R. C. H., Fong, W., Ng, D. K. P. & Lo, P., 9 Dec 2021, In: Journal of Medicinal Chemistry. 64, 23, p. 17455–17467

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 16
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  5. Published

    Novel Electrophilic Warhead Targeting a Triple-Negative Breast Cancer Driver in Live Cells Revealed by "inverse Drug Discovery"

    Fan, Y., Si, H., Zhang, Z., Zhong, L., Sun, H., Zhu, C., Yin, Z., & 7 othersLi, H., Tang, G., Yao, S. Q., Sun, P., Zhang, Z., Ding, K. & Li, Z., 11 Nov 2021, In: Journal of Medicinal Chemistry. 64, 21, p. 15582–15592

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 13
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  6. 2020
  7. Published

    Methylation of Daptomycin Leading to the Discovery of Kynomycin, a Cyclic Lipodepsipeptide Active against Resistant Pathogens

    Chow, H. Y., Po, K. H. L., Gao, P., Blasco, P., Wang, X., Li, C., Ye, L., & 7 othersJin, K., Chen, K., Chan, E. W. C., You, X., Yi Tsun Kao, R., Chen, S. & Li, X., 26 Mar 2020, In: Journal of Medicinal Chemistry. 63, 6, p. 3161-3171

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 26
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  8. 2019

  9. New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action

    Ohui, K., Afanasenko, E., Bacher, F., Ting, R. L. X., Zafar, A., Blanco-Cabra, N., Torrents, E., & 10 othersDömötör, O., May, N. V., Darvasiova, D., Enyedy, É. A., Popović-Bijelić, A., Reynisson, J., Rapta, P., Babak, M. V., Pastorin, G. & Arion, V. B., 24 Jan 2019, In: Journal of Medicinal Chemistry. 62, 2, p. 512-530

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 99
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  10. 2018
  11. Published

    Endoplasmic Reticulum-Localized Two-Photon-Absorbing Boron Dipyrromethenes as Advanced Photosensitizers for Photodynamic Therapy

    Zhou, Y., Cheung, Y., Ma, C., Zhao, S., Gao, D., Lo, P., Fong, W., & 2 othersWong, K. S. & Ng, D. K. P., 10 May 2018, In: Journal of Medicinal Chemistry. 61, 9, p. 3952-3961

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 60
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  12. 2017
  13. Published

    A Rhodium(III)-Based Inhibitor of Lysine-Specific Histone Demethylase 1 as an Epigenetic Modulator in Prostate Cancer Cells

    Yang, C., Wang, W., Liang, J., Li, G., Vellaisamy, K., Wong, C., Ma, D., & 1 othersLeung, C., 23 Mar 2017, In: Journal of Medicinal Chemistry. 60, 6, p. 2597-2603

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 66
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  14. 2014

  15. A dual activatable photosensitizer toward targeted photodynamic therapy

    Lau, J. T. F., Lo, P., Jiang, X., Wang, Q. & Ng, D. K. P., 22 May 2014, In: Journal of Medicinal Chemistry. 57, 10, p. 4088-4097

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 110
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  16. 2013

  17. Preparation and in vitro photodynamic activities of folate-conjugated distyryl boron dipyrromethene based photosensitizers

    Ke, M., Yeung, S., Ng, D. K. P., Fong, W. & Lo, P., 14 Nov 2013, In: Journal of Medicinal Chemistry. 56, 21, p. 8475-8483

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 86
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  18. 2012

  19. A zinc(II) phthalocyanine conjugated with an oxaliplatin derivative for dual chemo- and photodynamic therapy

    Lau, J. T. F., Lo, P., Fong, W. & Ng, D. K. P., 14 Jun 2012, In: Journal of Medicinal Chemistry. 55, 11, p. 5446-5454

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 105
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  20. 2011

  21. Synthesis and in vitro photodynamic activities of pegylated distyryl boron dipyrromethene derivatives

    He, H., Lo, P., Yeung, S., Fong, W. & Ng, D. K. P., 28 Apr 2011, In: Journal of Medicinal Chemistry. 54, 8, p. 3097-3102

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 66
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  22. Phthalocyanine-polyamine conjugates as highly efficient photosensitizers for photodynamic therapy

    Jiang, X., Yeung, S., Lo, P., Fong, W. & Ng, D. K. P., 13 Jan 2011, In: Journal of Medicinal Chemistry. 54, 1, p. 320-330

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 122
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  23. 2009

  24. Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers

    Lo, P., Chen, J., Stefflova, K., Warren, M. S., Navab, R., Bandarchi, B., Mullins, S., & 3 othersTsao, M., Cheng, J. D. & Zheng, G., 22 Jan 2009, In: Journal of Medicinal Chemistry. 52, 2, p. 358-368

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 98
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  25. 2008
  26. Published

    Surprising alteration of antibacterial activity of 5″-modified neomycin against resistant bacteria

    Zhang, J., Chiang, F., Wu, L., Czyryca, P. G., Li, D. & Chang, C. T., 11 Dec 2008, In: Journal of Medicinal Chemistry. 51, 23, p. 7563-7573

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 81
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  27. Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain

    Irie, O., Kosaka, T., Ehara, T., Yokokawa, F., Kanazawa, T., Hirao, H., Iwasaki, A., & 16 othersSakaki, J., Teno, N., Hitomi, Y., Iwasaki, G., Fukaya, H., Nonomura, K., Tanabe, K., Koizumi, S., Uchiyama, N., Bevan, S. J., Malcangio, M., Gentry, C., Fox, A. J., Yaqoob, M., Culshaw, A. J. & Hallett, A., 25 Sept 2008, In: Journal of Medicinal Chemistry. 51, 18, p. 5502-5505

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 34
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  28. 2007

  29. Highly photocytotoxic glucosylated silicon(IV) phthalocyanines. Effects of peripheral chloro substitution on the photophysical and photodynamic properties

    Lo, P., Chan, C. M. H., Liu, J., Fong, W. & Ng, D. K. P., 3 May 2007, In: Journal of Medicinal Chemistry. 50, 9, p. 2100-2107

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 96
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  30. 2006

  31. Synthesis and biological evaluation of purealin and analogues as cytoplasmic dynein heavy chain inhibitors

    Zhu, G., Yang, F., Balachandran, R., Höök, P., Vallee, R. B., Curran, D. P. & Day, B. W., 23 Mar 2006, In: Journal of Medicinal Chemistry. 49, 6, p. 2063-2076

    Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

    Scopus citations: 41
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