Researchers discover conjugative plasmid that augments virulence in superbug
Press/Media: Press / Media
|Title||Researchers discover conjugative plasmid that augments virulence in superbug|
|Description||Further experiments by the research team led by Professor Chen Sheng discovered that the new-found plasmid could travel from one bacterium to another. The transfer of this virulence plasmid to a carbapenem-resistant Klebsiella pneumoniae strain can result in a significant increase in the virulence level of such strain, making it both carbapenem-resistant and hyper-virulent.|
The new findings were published in Nature Microbiology end of September.
|Media name/outlet||News Medical Life Sciences|
|Title||A weapon to make a superbug to become more deadly|
|Description||A recent research led by Professor Chen Sheng, Acting Head of Department of Infectious Diseases and Public Health at City University of Hong Kong (CityU) has discovered an easily transmitted DNA piece that can make a new type of hyper-resistant and deadly superbug become hyper-virulent quickly, posing an unprecedented threat to human health. |
Based on this finding and more data from his team, Professor Cheng and his team will continue to investigate more clinical Klebsiella penumoniae strains to discover more different types of conjugative virulence plasmids, which attribute to the current emergence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae.
|Media name/outlet||CityU Research Stories|